Results 251 to 260 of about 261,257 (360)

Early acclimatization to high altitude: Acid–base and fluid balance dynamics during the first 2 days at 3100 m

open access: yesExperimental Physiology, EarlyView.
Abstract Immediate responses to hypoxia at high altitude are hyperventilation and successive respiratory alkalosis. Alkalosis, in turn, can affect cerebrospinal fluid pH and ventilatory control. The kidneys compensate metabolically for respiratory alkalosis.
Elisabeth Skalla   +9 more
wiley   +1 more source

Role of S1P‐ and Rho‐kinase signalling in age‐related myogenic tone deficiency in murine resistance arteries

open access: yesExperimental Physiology, EarlyView.
Abstract Ageing is a risk factor for cardiovascular and neurodegenerative diseases. The myogenic response in resistance arteries is responsible for basal (myogenic) tone and blood flow autoregulation. G‐protein‐coupled receptors and G12/RhoA/Rho kinase are implicated in myogenic tone (MT), and we aimed to clarify their role in pressure sensing and ...
Gry Freja Skovsted   +11 more
wiley   +1 more source

Targeting Cardiac Mast Cells: Pharmacological Modulation of the Local Renin-Angiotensin System

open access: green, 2011
Alicia C. Reid   +4 more
openalex   +2 more sources

Cardiac remodelling in type 2 diabetes: Pathophysiological mechanisms and opportunities for multiscale computational modelling and simulation

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Overview of multiscale cardiac remodelling in type 2 diabetes and how to model and simulate these changes using a human‐based, multiscale computational framework. Cardiac remodelling in type 2 diabetes occurs at ionic channel, protein, cellular, tissue and whole‐organ level, affecting the electrophysiological function, mechanical
Ambre Bertrand   +2 more
wiley   +1 more source

Editorial: Proceedings of KININ2018CLE, Cleveland, Ohio, June 18-20, 2018: A Compendium of the Presentations

open access: yesFrontiers in Medicine, 2019
Alvin H. Schmaier   +4 more
doaj   +1 more source

The renin phenotype: roles and regulation in the kidney

open access: green, 2010
Maria Luisa S. Sequeira-Lόpez   +1 more
openalex   +2 more sources

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