Results 61 to 70 of about 240,790 (255)
Background: The renin angiotensin aldosterone system (RAAS) plays a vital role in regulating glucose metabolism and blood pressure, electrolyte and fluid homeostasis.
Zohreh Rahimi+2 more
doaj
Plasma Angiotensin II Is Increased in Critical Coronavirus Disease 2019
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) employs angiotensin-converting enzyme 2 (ACE2) as its receptor for cell entrance, and studies have suggested that upon viral binding, ACE2 catalytic activity could be inhibited; therefore ...
Rafael L. Camargo+20 more
doaj +1 more source
Advantages of the new loop diuretic torasemide over furosemide in patients with cirrhosis and ascites [PDF]
Torasemide is a new loop diuretic with a longer half-life and longer action than furosemide in healthy subjects. In order to evaluate the pharmacodynamic effects, single oral doses of furosemide (80 mg) and torasemide (20 mg), which were equipotent in ...
Bertheau-Reitha, Ute+4 more
core +1 more source
Emerging pharmacological treatments to prevent abdominal aortic aneurysm growth and rupture [PDF]
Abdominal aortic aneurysm (AAA) is a local expansion of the abdominal aorta wall caused by a complex multifactorial maladaptive vascular remodeling. Despite recent advances in the management of cardiovascular diseases, there currently is no established ...
Fraga-Silva, Rodrigo+2 more
core +2 more sources
RAA System and Exercise Relationship
In this review, it is aimed to discuss the possible interactions between renin-angiotensin-aldosterone system and exercise for health and performance and to present new literature on this subject.
Sadettin Ünsal, Suleyman Patlar
doaj +1 more source
Propensity scores using missingness pattern information: a practical guide [PDF]
Electronic health records are a valuable data source for investigating health-related questions, and propensity score analysis has become an increasingly popular approach to address confounding bias in such investigations. However, because electronic health records are typically routinely recorded as part of standard clinical care, there are often ...
arxiv
Differential renal effects of candesartan at high-and ultra-high doses in diabetic mice: potential role of ACE2/AT2R/Mas [PDF]
High doses of Ang II receptor (AT1R) blockers (ARBs) are renoprotective in diabetes. Underlying mechanisms remain unclear. We evaluated whether high/ultra-high doses of candesartan (ARB) up-regulate angiotensin-converting enzyme 2 (ACE2)/Ang II type 2 ...
Antunes, Tayze+10 more
core +1 more source
Renin as a target of direct pharmacological block in arterial hypertension
Renin is a basic component of renin-angiotensin-aldosteron system which contributes much to the activity of this system. Renin and its precursor prorenin can interact with prorenin receptors thus inducing hypertrophy and fibrogenesis in target tissues ...
Nikolay Alekseevich Mukhin+3 more
doaj
The renin-angiotensin-aldosterone system (RAAS) plays an important role in regulating hypertension by controlling vasoconstriction and intravascular fluid volume. RAAS itself is largely regulated by the actions of renin (EC 3.4.23.15) and the angiotensin-
Stephen Bleakley+4 more
doaj +1 more source
Hyporeninemic hypoaldosteronism in a patient with diabetes mellitus: an unforgettable case report
Naziha Chelaghma, Samson O Oyibo Department of Diabetes & Endocrinology, Peterborough City Hospital, Peterborough, UK Abstract: A 58-year-old man presented with a 3-year history of chronic and intermittent hyperkalemia requiring recurrent ...
Chelaghma N, Oyibo SO
doaj