Results 61 to 70 of about 217,588 (352)

Cardiomyocyte‐Enriched USP20 Ameliorates Pathological Cardiac Hypertrophy by Targeting STAT3 Deubiquitination

open access: yesAdvanced Science, EarlyView.
Cardiomyocyte‐enriched USP20 regulates the K63‐linked ubiquitination of STAT3, and the cardiomyocyte‐specific USP20‐STAT3‐CARM1 axis exerts a protective role in cardiac hypertrophy. Targeting USP20 through cardiac‐specific gene therapy presents a promising strategy for the treatment of cardiac hypertrophy.
Lingfeng Zhong   +15 more
wiley   +1 more source

Reminiscences of Ervin G Erdös [PDF]

open access: yesScripta Medica, 2019
This article includes personal reminiscence of the great scientist Ervin G Erdös (1922-2019). Dr Erdös was born in Budapest, where he studied medicine. He finished his medical school in Munich, and obtained MD degree in 1952.
Igić Rajko
doaj  

Effect of calcifediol supplementation on renin‐angiotensin‐aldosterone system mediators in dogs with chronic kidney disease

open access: yesJournal of Veterinary Internal Medicine, 2022
Background Chronic kidney disease (CKD) leads to low serum concentrations of vitamin D metabolites. Thus, hypovitaminosis D associated with CKD might contribute to disease progression via increased concentration of renin angiotensin aldosterone system ...
Matthew Miller   +4 more
doaj   +1 more source

The modelling of COVID19 pathways sheds light on mechanisms, opportunities and on controversial interpretations of medical treatments. v2 [PDF]

open access: yesarXiv, 2020
The new coronavirus (2019-nCoV or SARS-CoV2), inducing the current pandemic disease (COVID-19) and causing pneumoniae in humans, is dramatically increasing in epidemic scale since its first appearance in Wuhan, China, in December 2019. The first infection from epidemic coronaviruses in 2003 fostered the spread of an overwhelming amount of related ...
arxiv  

Food protein-derived renin-inhibitory peptides: in vitro and in vivo properties.

open access: yesJournal of food biochemistry, 2018
Renin catalyzes the rate-determining step in the renin-angiotensin-aldosterone system that regulates mammalian blood pressure by converting angiotensinogen to angiotensin I (Ang I).
R. Aluko
semanticscholar   +1 more source

A Touch Enabled Hemodynamic and Metabolic Monitor

open access: yesAdvanced Science, EarlyView.
This work presents a touch‐based hybrid platform for simultaneous monitoring of vital signs and sweat metabolites. With a simple tri‐finger touch of 4–6 min, users can concurrently get to know their glucose, uric acid, cortisol levels from fingertip sweat, along with blood pressure and heart rate.
Omeed Djassemi   +19 more
wiley   +1 more source

Continuum of Renin-Independent Aldosteronism in Normotension

open access: yesHYPERTENSION, 2017
Primary aldosteronism is a severe form of autonomous aldosteronism. Milder forms of autonomous and renin-independent aldosteronism may be common, even in normotension.
R. Baudrand   +6 more
semanticscholar   +1 more source

Adverse Cardiovascular Risk Profile and Increased Diurnal Salivary Cortisol in Girls With Turner Syndrome: An Exploratory Study

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Patients with Turner Syndrome (TS) and those exposed to high concentrations of glucocorticoids have a number of characteristics in common, including an increased risk of cardiovascular disease. Pediatric TS patients underwent studies of salivary cortisol (SC) and cortisone (SCn), body composition, continuous glucose monitoring, vascular ...
Lily Jones   +6 more
wiley   +1 more source

Sodium butyrate suppresses angiotensin II-induced hypertension by inhibition of renal (pro)renin receptor and intrarenal renin–angiotensin system

open access: yesJournal of Hypertension, 2017
Objectives: Butyrate, a short-chain fatty acid, is the end product of the fermentation of complex carbohydrates by the gut microbiota. Recently, sodium butyrate (NaBu) has been found to play a protective role in a number of chronic diseases.
Lei Wang   +8 more
semanticscholar   +1 more source

1,25-Dihydroxyvitamin D3 is a negative endocrine regulator of the renin-angiotensin system

open access: yes, 2002
Inappropriate activation of the renin-angiotensin system, which plays a central role in the regulation of blood pressure, electrolyte, and volume homeostasis, may represent a major risk factor for hypertension, heart attack, and stroke. Mounting evidence
Y. Li   +5 more
semanticscholar   +1 more source

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