Results 201 to 210 of about 3,459,561 (335)

Comprehensive Management of Hyperkalaemia in Patients with Chronic Kidney Disease and Cardiovascular Conditions: Expert Recommendations from Mexico. [PDF]

Card Fail Rev
Méndez-Durán A, Ivey-Miranda JB, Mendoza-Zavala GH, Álvarez-Sangabriel A, Sánchez-Guerrero DC, Díaz-García JD, Borges-Vela JA, Morales-Buenrostro LE, Quilantán-Rodríguez M, Ruíz-Mejía R, Chávez-Leal SA.   +10 more
europepmc   +1 more source

Hyperaldosteronism in the Pathophysiology and Management of Cardiovascular-Kidney-Metabolic Syndrome. [PDF]

Diabetes Obes Metab
ABSTRACT Cardiovascular‐kidney‐metabolic (CKM) syndrome is defined by the pathologic interconnections between obesity, diabetes, chronic kidney disease and cardiovascular disease. An important and underrecognized pathophysiologic factor underlying CKM syndrome is obesity‐induced aldosterone excess.
Zeitler E, Klein KR, Lingvay I, Pick A, Billings LK.   +4 more
europepmc   +2 more sources

Interindividual variability in static apnoea performance is partly explained by genetic factors

Experimental Physiology, EarlyView.
Abstract A large interindividual variability exists in maximal apnoea duration and the physiological adjustments that occur during apnoea. Although a few genes have been found to be associated with some of the cardiovascular responses during apnoea, the extent to which genetic and environmental factors contribute to individual differences in apnoea ...
Anastasios Makris, Alexandros Sotiridis, Nickos Geladas, Kalliopi Gkouskou, Vassilis Klissouras, Maria D. Koskolou   +5 more
wiley   +1 more source

Aldosterone synthesis inhibitors in resistant hypertension: the BaxHTN trial. [PDF]

Eur Heart J Suppl
Gallo G, Volterrani M, Tocci G, Volpe M.
europepmc   +1 more source

Effects of reducing sedentary behaviour on heart rate variability and cardio‐metabolic biomarkers in desk workers with untreated high blood pressure

Experimental Physiology, EarlyView.
Abstract Lower sedentary behaviour (SB) has been associated with reduced cardiovascular disease and mortality. Yet, few trials have evaluated cardiovascular mechanisms of benefit. We examined the effects of a SB reduction intervention on heart rate variability (HRV) and cardio‐metabolic biomarkers.
Abdullah Bandar Alansare, Matthew F. Muldoon, Subashan Perera, Kimberly A. Huber, Molly B. Conroy, John M. Jakicic, Bethany Barone Gibbs   +6 more
wiley   +1 more source

Is Obesity a Major Driver of Primary Aldosteronism? [PDF]

JACC Basic Transl Sci
Hall JE, Omoto ACM, Hall ME.
europepmc   +1 more source

Neuroprotective roles of klotho: Molecular pathways and therapeutic implications for cognitive health in neurological and psychiatric diseases

Experimental Physiology, EarlyView.
Abstract Klotho, a pleiotropic protein initially identified for its role in kidney function, has garnered significant attention for its neuroprotective properties in various neurodegenerative diseases. It regulates key processes, such as oxidative stress, neuroinflammation, synaptic plasticity and myelination, all crucial for maintaining neuronal ...
Amir Arsalan Ghahari, Leylinaz Safaeihavadaragh, Mehrdad Nourizadeh, Shaghayegh Davari, Saba Safaei, Farshad Zare, Safa Alkayyat, Erfan Kamali Far   +7 more
wiley   +1 more source

Causal Effects of Renin-Angiotensin-Aldosterone System Inhibition on Renal Function in Patients With Chronic Kidney Disease: A Quasi-Experimental Study. [PDF]

Clin Transl Sci
Oh TR, Park J, Choi HS, Rhee H, Kang G.
europepmc   +1 more source

Cardiac remodelling in type 2 diabetes: Pathophysiological mechanisms and opportunities for multiscale computational modelling and simulation

The Journal of Physiology, EarlyView.
Abstract figure legend Overview of multiscale cardiac remodelling in type 2 diabetes and how to model and simulate these changes using a human‐based, multiscale computational framework. Cardiac remodelling in type 2 diabetes occurs at ionic channel, protein, cellular, tissue and whole‐organ level, affecting the electrophysiological function, mechanical
Ambre Bertrand, Jakub Tomek, Blanca Rodriguez   +2 more
wiley   +1 more source