Results 291 to 300 of about 3,459,561 (335)

Competitive inhibitors of renin

Biochemistry, 1973
K, Poulsen, J, Burton, E, Haber
openaire   +3 more sources

Renin inhibitors in hypertension.

Clinical nephrology, 1992
The renin-angiotensin system (RAS) is an important modulator of blood pressure and fluid balance. The clinical success of angiotensin converting enzyme inhibitors (ACEIs) in the treatment of hypertension has stimulated the search for antagonists of renin.
R R, Luther, H N, Glassman, R S, Boger
openaire   +1 more source

[Renin, prorenin, and the direct renin inhibitor aliskiren].

Casopis lekaru ceskych, 2010
The renin-angiotensin system plays an important role in various physiological and pathophysiological regulatory mechanisms. Within the past few years, the classical concept of a linear enzymatic cascade has experienced substantial changes. A parallel counterregulatory axis has been identified which involves the angiotensin converting enzyme homologue ...
Adolf, Slabý, Ales, Zák
openaire   +1 more source

2 Renin Inhibitors

1995
Publisher Summary This chapter focuses on renin inhibitors. Renin is the first and rate-limiting enzyme in the renin angiotensin system (RAS). It is a 3740 Kd glycoprotein that is secreted primarily by the juxtaglomerular cells in the kidney in response to decreased perfusion pressure or a fall in plasma sodium concentration.
openaire   +1 more source

Renin‐Angiotensin System Inhibitors in Patients With COVID‐19: A Meta‐Analysis of Randomized Controlled Trials Led by the International Society of Hypertension

Journal of the American Heart Association, 2022
Sonali R Gnanenthiran, Claudio Borghi, Bruno Caramelli   +2 more
exaly  

Renin Angiotensin Aldosterone System Inhibitors in Hypertension: Is There Evidence for Benefit Independent of Blood Pressure Reduction?

Progress in cardiovascular diseases, 2016
Chirag P Bavishi, S. Bangalore, F. Messerli   +2 more
semanticscholar   +1 more source

Renin-angiotensin-aldosterone system inhibition: overview of the therapeutic use of angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, mineralocorticoid receptor antagonists, and direct renin inhibitors.

Primary Care, 2014
Kelly Mercier, H. Smith, Jason I. Biederman   +2 more
semanticscholar   +1 more source

Topomer CoMFA and virtual screening studies of azaindole class renin inhibitors.

Combinatorial chemistry & high throughput screening, 2014
Yuhong Xiang, Jia Song, Zhuoyong Zhang
semanticscholar   +1 more source

Renin–angiotensin–aldosterone system inhibitors and survival in patients with hypertension treated with immune checkpoint inhibitors

European Journal of Cancer, 2022
Zsófia Dora Drobni, Olivier Michielin, Thiago Quináglia   +2 more
exaly  

Renin Inhibitors and Cardiovascular and Renal Protection: An Endless Quest?

Cardiovascular Drugs and Therapy, 2013
M. Azizi, J. Ménard
semanticscholar   +1 more source