Results 301 to 310 of about 3,459,561 (335)

Potential virtual lead identification in the discovery of renin inhibitors: application of ligand and structure-based pharmacophore modeling approaches.

European journal of medicinal chemistry, 2011
S. Thangapandian, Shalini John, S. Sakkiah, Keun Woo Lee   +3 more
semanticscholar   +1 more source

Structure-based design and optimization of potent renin inhibitors on 5- or 7-azaindole-scaffolds.

Bioorganic & Medicinal Chemistry Letters, 2011
H. Matter, B. Scheiper, H. Steinhagen, Z. Böcskei, V. Fleury, G. Mccort   +5 more
semanticscholar   +1 more source

Renin inhibitors for the treatment of hypertension: design and optimization of a novel series of pyridone-substituted piperidines.

Bioorganic & Medicinal Chemistry Letters, 2011
Austin Chen, Louis-Charles Campeau, E. Cauchon, Amandine Chefson, Y. Ducharme, D. Dubé, J. Falgueyret, P. Fournier, S. Gagné, E. Grimm, Yongxin Han, R. Houle, Jing-Qi Huang, P. Lacombe, Sébastien Laliberté, Jean-François Lévesque, Susana Liu, D. Macdonald, B. Mackay, D. McKay, M. Percival, C. Regan, H. Regan, René St-Jacques, S. Toulmond   +24 more
semanticscholar   +1 more source

High Resolution Crystal Structures of Recombinant Human Renin in Complex with Polyhydroxymonoamide Inhibitors

Journal of Molecular Biology, 1995
Liang Tong, Daniel Lamarre, D Lamarre
exaly  

Comparative Modeling of Proteins in the Design of Novel Renin Inhibitors

Critical Reviews in Biochemistry and Molecular Biology, 1991
Jonathan Greer, Dennis J Hoover, J Greer   +2 more
exaly  

Design and synthesis of potent macrocyclic renin inhibitors.

Bioorganic & Medicinal Chemistry Letters, 2011
C. Sund, O. Belda, D. Wiktelius, C. Sahlberg, L. Vrang, S. Sedig, Elizabeth Hamelink, Ian R. Henderson, Tatiana Agback, K. Jansson, N. Borkakoti, D. Derbyshire, A. Eneroth, B. Samuelsson   +13 more
semanticscholar   +1 more source

Renin Inhibitors

1990
R. Henning, A. Wagner, B. A. Schölkens
openaire   +1 more source

Renin inhibitors for the treatment of hypertension: design and optimization of a novel series of spirocyclic piperidines.

Bioorganic & Medicinal Chemistry Letters, 2011
Austin Chen, Renée Aspiotis, Louis-Charles Campeau, E. Cauchon, Amadine Chefson, Y. Ducharme, J. Falgueyret, S. Gagné, Yongxin Han, R. Houle, Sébastien Laliberté, G. Larouche, Jean-François Lévesque, D. McKay, D. Percival   +14 more
semanticscholar   +1 more source

Renin inhibitors for the treatment of hypertension: design and optimization of a novel series of tertiary alcohol-bearing piperidines.

Bioorganic & Medicinal Chemistry Letters, 2011
Austin Chen, E. Cauchon, Amandine Chefson, S. Dolman, Y. Ducharme, D. Dubé, J. Falgueyret, P. Fournier, S. Gagné, M. Gallant, E. Grimm, Yongxin Han, R. Houle, Jing-Qi Huang, G. Hughes, H. Jûteau, P. Lacombe, Sophie Lauzon, Jean-François Lévesque, Susana Liu, D. Macdonald, B. Mackay, D. McKay, M. Percival, René St-Jacques, S. Toulmond   +25 more
semanticscholar   +1 more source

Discovery of non-peptidic P 2 –P 3 butanediamide renin inhibitors with high oral efficacy

Bioorganic and Medicinal Chemistry, 1999
Pierre Lavallée, Gulrez Fazal, William W Ogilvie   +2 more
exaly