Results 141 to 150 of about 25,961 (244)

O-GlcNAcylation of YAP1 promotes lung transplant ischemia-reperfusion injury via binding to HIF1α transcription factor and activating autophagy and mitophagy. [PDF]

Cell Death Dis
Dai S, Wan X, Xia L, Xu L, Xie C, Wang G, Tang J.   +6 more
europepmc   +1 more source

Encephalopathy: Cause, Pathogenesis, and Treatment

MedComm, Volume 7, Issue 6, June 2026.
Various encephalopathies (sepsis‐associated, hepatic, hypoxic–ischemic, diabetic, uremic, toxic) have incompletely elucidated pathogenesis, which severely restricts targeted therapy development. Small molecule drugs show unique multitarget potential but face toxicity, poor blood–brain barrier penetration and unclear specificity.
Shimeng Lv, Xia Zhong, Ruirui Shang, Linghui Kong, Yufei Huang, Yuexiang Ma, Jing Teng, Sheng Wei   +7 more
wiley   +1 more source

Root morphogenetic responses to waterlogging stress in plants: from structural reconfiguration to molecular regulatory mechanisms. [PDF]

Front Plant Sci
Sha S, Zeng C, Shang X, Zou B, Sun T, Yang Y.   +5 more
europepmc   +1 more source

<i>Tongmai Yangxin</i> pills alleviate myocardial ischemia-reperfusion injury by enhancing mitochondrial function <i>via</i> activating the ERK signaling pathway. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Wang Y, Song Z, Guo L, Xiao Y, Chen R, Wang Y.   +5 more
europepmc   +1 more source

Circadian Immunity and Vascular Inflammation in Cardiovascular Disease Chronotherapy Windows: Time for a Re‐Assessment

Med Research, Volume 2, Issue 2, Page 236-279, June 2026.
ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang, Ge Zhang, Tian‐Ding Liu, Tianshu Gu, Fengyi Yu, Pengyuan Xu, Wunan Mi, Xuanjiang Zhao, Qian Guo, Honglin Zheng, Taiqi Zhao, Qiang Li, Di Lu, Mingxuan Duan, Chaoyang Yu, Ruhao Wu, Shiqian Zhang, Haonan Zhang, Zeyu Wang, Youyang Zheng, Yan Xiao, Zenglei Zhang, Ge Zhang   +22 more
wiley   +1 more source

Oxygen-dependent modulation of the human complement system during acute normobaric hypoxia: a translational plasma proteomics study. [PDF]

Clin Exp Med
Lang A, Pang TY, Piel S, Oehler D, Zweck E, Shahrjerdi K, Okkasian M, Georgy J, Reinders Y, Duplessis AJ, Tank J, Jordan J, Pfeiler S, Sickmann A, Kelm M, Jung C, Gerdes N.   +16 more
europepmc   +1 more source

A new perspective on radiotherapy in the comprehensive treatment of cancer

Precision Radiation Oncology, Volume 10, Issue 2, Page 165-183, June 2026.
Radiotherapy remains a key component in the comprehensive management of cancer. Its effectiveness is significantly improved through strategic combinations with chemotherapy, targeted therapy, and immunotherapy, providing a range of therapeutic outcomes from cure to palliative care.
Yingze Ma, Hongxuan Yu, Shijie Shang, Shixin Shan, Dawei Chen   +4 more
wiley   +1 more source

Long non-coding RNA transcripts in crucian carp brain - annotation and expression patterns in anoxia and reoxygenation. [PDF]

RNA Biol
Winklhofer M, Nilsson GE, Lefevre S.
europepmc   +1 more source

Kaempferol Improves Alzheimer's Disease by Inhibiting Neuronal Ferroptosis via Activating GPX4/AKR1C3 Signaling Pathway

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Kaempferol has been shown to be beneficial in the treatment of Alzheimer's disease (AD) in animal models. However, the action mechanism remains unclear. AKR1B1 has been identified as a target of kaempferol, initially suggested by the Therapeutic Target Database, DrugBank, and PubChem, and subsequently confirmed through experimental validation.
Le Li, Manying Yang, Jiale Tao, Yonghong Zhao, Na Zhao, Shiguo Sun   +5 more
wiley   +1 more source

Hypoxia-induced gene expression changes in N. vectensis embryos. [PDF]

Sci Rep
Hadife S, Wang H, Hongo Y, Watanabe H.
europepmc   +1 more source