Results 151 to 160 of about 25,961 (244)

In Vitro Analysis of TWEAK/Fn14 Axis in the Blood-Brain Barrier Models during Oxygen-Glucose Deprivation and Reoxygenation. [PDF]

Mol Neurobiol
Sampedro-Viana A, Alonso-Alonso ML, Castillo J, Hervella P, Álvarez E, Burek M, Iglesias-Rey R.   +6 more
europepmc   +1 more source

The NF‐κB Signalling Pathway: Mechanisms, Consequences and Therapeutic Targets

Journal of Cellular and Molecular Medicine, Volume 30, Issue 11, June 2026.
ABSTRACT Nuclear Factor‐kappa B (NF‐κB) is a master transcriptional regulator orchestrating critical cellular processes, predominantly immunity and inflammation. However, its aberrant constitutive activation has emerged as a unifying pathogenetic hallmark across diverse malignancies, autoimmune disorders, and chronic inflammatory diseases.
Bherouz Pourdad, Arash Pourdad
wiley   +1 more source

Optimal radiotherapy dose scheduling with variable fraction sizes and breaks via sequential mixed-integer convex programming. [PDF]

Phys Imaging Radiat Oncol
Fu A, Gouw Z, Jeong J, Deasy JO.
europepmc   +1 more source

Superoxide Dismutase–Centered Modulation by Curcumin in Cardiovascular Diseases: Mechanistic Insights and Translational Implications

Journal of Cellular and Molecular Medicine, Volume 30, Issue 11, June 2026.
ABSTRACT Cardiovascular diseases (CVD) remain the leading global cause of morbidity and mortality, driven in part by dysregulated redox homeostasis and chronic inflammation. Superoxide dismutase (SOD), a key enzymatic defence against reactive oxygen species (ROS), plays a central role in maintaining cardiovascular integrity through regulation of ...
Danial Khayatan, Seyed Mehrad Razavi, Zahra Najafi Arab, Amirhossein Niknejad, Yasamin Hosseini, Ayeh Sabbagh Kashani, Saeideh Momtaz, Tannaz Jamialahmadi, Prashant Kesharwani, Amir Hossein Abdolghaffari, Amirhossein Sahebkar   +10 more
wiley   +1 more source

Prenylcysteine Oxidase 1 Deficiency Protects the Cardiac Muscle Cell Line HL-1 Against Ischaemic/Hypoxic Stress. [PDF]

FASEB J
Banfi C, Brocca L, Bascucci A, Papaianni GG, Mallia A, Eligini S.   +5 more
europepmc   +1 more source

Potential Relationship Between YTHDF3 and CFTR in Myocardial Ischemia–Reperfusion Injury

Journal of Cellular and Molecular Medicine, Volume 30, Issue 11, June 2026.
ABSTRACT Myocardial ischemia–reperfusion injury (MIRI) is a common pathophysiological process in reperfusion therapy following myocardial infarction. It exacerbates myocardial damage and negatively impacts patient prognosis. This study aims to explore potential regulatory targets and related mechanisms in MIRI.
Baoxin Tang, Chenying Zhu, Heqing Wang, Mingkui Gao, Tieyan Li   +4 more
wiley   +1 more source

Assessment of hESC‐IMRC‐Exo for Cardiac and Cerebral Injuries Post‐Cardiac Arrest Resuscitation: Safety, Pharmacokinetics, and Efficacy

Journal of Cellular and Molecular Medicine, Volume 30, Issue 12, June 2026.
ABSTRACT Cardiac arrest (CA) is a leading cause of death globally. Exosomes derived from mesenchymal stem cells exhibit favourable production, storage, and safety characteristics, making them a promising alternative for post‐CA resuscitation. We assessed the safety, biodistribution, and protective effects of human embryonic stem cell‐derived immunity ...
Huijuan Yang, Xiaodan Zhang, Wenbin Zhang, Xue Wang, Jie Wang, Ziwei Chen, Jinyu Zhu, Yufeng Hu, Lu He, Licai Liang, Jiefeng Xu, Mao Zhang   +11 more
wiley   +1 more source

Inhibition of SUR1-TRPM4 attenuates astrocyte swelling and reactivity under oxygen-glucose deprivation/reoxygenation. [PDF]

PLoS One
Zhao Y, Pakaprot N, Sutiwisesak R, Vattarakorn U, Tapechum S.   +4 more
europepmc   +1 more source

Exposure to Gestational Intermittent Hypoxia Does Not Impair the Metabolic Function or Accelerate the Biological Ageing Process of Offspring of Either Sex

Journal of Sleep Research, Volume 35, Issue 3, June 2026.
ABSTRACT Obstructive sleep apnea (OSA), marked by intermittent hypoxia, is associated with obesity, type 2 diabetes and metabolic associated fatty liver disease. In pregnancy, it remains underdiagnosed despite links to gestational diabetes, hypertension, and foetal growth restriction.
Esther Valverde‐Perez, Margarida B. Almeida, Joana F. Sacramento, Elena Olea, Jesus Prieto‐Lloret, Asuncion Rocher, Silvia V. Conde   +6 more
wiley   +1 more source

Salvianic Acid A Regulates Ferroptosis by Activating the Nrf2-GPX4 Pathway Through EGFR to Protect Myocardial Ischemia-Reperfusion Injury. [PDF]

J Inflamm Res
Tu L, Lu Y, Liu X, Shen X.
europepmc   +1 more source