Results 131 to 140 of about 25,961 (244)

Liensinine Ameliorating Oxidative Damage to Vascular Endothelium In Vitro via Upregulating eNOS and Nrf2/HO‐1 Signaling

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
The present studies of network pharmacology, molecular docking and molecular dynamics simulation indicated that liensinine might ameliorate oxidative damage to vascular endothelium (ODVE) by regulating the targets of Nrf2, which is encoded by the NFE2L2 gene. Then the in vitro study further showed that liensinine exhibited an obvious protection against
Feng Gao, Fengjiao Deng, Qiaowei Du, Tianya Xia, Yayi Deng, Shuang Liu, Bin Yu, Chenxiao Shan   +7 more
wiley   +1 more source

Skeletal Muscle Blood Flow and NIRS Oxygenation Kinetics as a Tool to Evaluate Adaptations to High-Intensity Exercise Training. [PDF]

Sensors (Basel)
Lesmana HS, Rodrigues P, Simpson LL, Marume K, Perkins DR, Lawley JS.   +5 more
europepmc   +1 more source

Comparative Analysis of Extracellular Vesicle‐Like Particles From Different Processing Gastrodia elata Bl.: Physicochemical Properties, Biosafety, and Neuroprotection Potential as a Functional Food Ingredient

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
This study systematically characterizes extracellular vesicle‐like particles (EVLPs) from three processed Gastrodia elata forms (dry, wine, and ginger), evaluating their physicochemical properties, metabolite profiles, biocompatibility, and neuroprotective efficacy in an OGD/R model, highlighting their neuroprotective potential as a functional food ...
Yuanyuan Qin, Shuming Li, Jia Yu, Jingyu Weng, Bo Li, Xinyi Liu, Ke Wang, Yuangui Yang, Honghong Jiao, Jiaofeng Wu, Hongbo Xu   +10 more
wiley   +1 more source

Oxygen equilibration dynamics in assisted reproductive technology embryo culture media. [PDF]

J Assist Reprod Genet
Kulkarni S, Morris BK, Krieg SA, O'Leary T, Krieg A.   +4 more
europepmc   +1 more source

Mitochondrial responses to anoxia-reoxygenation exposure in crucian carp (Carassius carassius). [PDF]

J Exp Biol
Lau GY, Gerber L, Johansen A, Dahl HA, Torp MK, Bates G, Murphy MP, Eide L, Stensløkken KO, Nilsson GE, Lefevre S.   +10 more
europepmc   +1 more source

Th17 cells favor migration and invasiveness of cervical cancer cells under hypoxia in an IGF2BP2‐dependent manner

International Journal of Cancer, Volume 158, Issue 11, Page 3021-3037, 1 June 2026.
What's new? Hypoxic regions and inflammatory Th17 cells in the tumor environment are both associated with poor prognosis in cervical cancer. However, synergistic mechanisms between hypoxia and Th17 cells remain elusive. This study demonstrated Th17–hypoxia‐driven mechanisms underlying cervical cancer progression.
Selina Gies, Maike Pohlers, Tanja Tänzer, Emmanuel Ampofo, Matthias W. Laschke, Moritz Schäfer, Yoo‐Jin Kim, Rainer Maria Bohle, Erich‐Franz Solomayer, Konrad Wagner, Martin Empting, Alexandra K. Kiemer, Barbara Walch‐Rückheim   +12 more
wiley   +1 more source

Apohemoglobin-haptoglobin complex is a therapeutic against vaso-occlusive crisis: scavenging of hemoglobin and heme. [PDF]

Blood Adv
Munoz CJ, Pires IS, Lucas D, Muller C, Martinez J, Gopal S, Palmer AF, Cabrales P.   +7 more
europepmc   +1 more source

Defining the Human Nucleus Pulposus Microenvironment and Its Impact on Cell Matrix Synthesis and Metabolic Activity

JOR SPINE, Volume 9, Issue 2, June 2026.
Human intervertebral disc nutrient microenvironment. Changes observed in microenvironmental profile as a result of degeneration outlined on upper vertebral body with ranges of each species as reported in previous studies. Oxygen, glucose, and lactate gradients are profiled across the lower disc in both healthy and degenerated states.
Niamh Wilson, Tara Ní Néill, Jake McDonnell, Emily McDonnell, Stacey Darwish, Joseph S. Butler, Conor T. Buckley   +6 more
wiley   +1 more source

Electron transfer flavoprotein subunit beta suppresses hypoxia/reoxygenation-induced mitochondrial dysfunction and apoptosis in cardiomyocytes. [PDF]

J Int Med Res
Liu J.
europepmc   +1 more source

Epigenetic Regulation in Cardiovascular Diseases: Mechanisms and Therapeutic Targets

MedComm, Volume 7, Issue 6, June 2026.
Environmental and lifestyle exposures reshape the cardiovascular epigenome through coordinated regulation of DNA methylation, histone modifications, noncoding RNAs, and RNA methylation (m6A). These multilayered mechanisms drive enhancer‐centered regulatory network remodeling and epigenomic plasticity in cardiovascular diseases, highlighting emerging ...
Wangzheqi Zhang, Chenyang Mu, Rui Zhao, Runwei Ma, Xuehai Liu, Haoling Zhang, Zengwu Wang, Jing‐jing Zhang   +7 more
wiley   +1 more source