Results 121 to 130 of about 25,961 (244)

Toosendanin Alleviates Cerebral Ischemia/Reperfusion Injury via Inhibiting Neural Ferroptosis Through Lipid Metabolic Reprogramming in MCAO Mice

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
Post‐stroke administration of TSN significantly reduced infarct volume, neuroinflammation, and improved functional recovery of MCAO mice. TSN alleviated neural oxidative stress, lipid peroxidation, and ferroptosis in MCAO mice. TSN modulated the infiltration of immune cells in MCAO mice in vivo and T cell differentiation in vitro.
Xinyun Li, Zhiyong Zhao, Jingting Zhao, Xiangming Ye, Zhenfei Xiong, Jiejin Zhao   +5 more
wiley   +1 more source

Photobiomodulation Alleviates Insulin Resistance Induced by Intermittent Hypoxia, Through Preservation of Adipose Tissue Insulin Signaling and Reduction of Hepatic Oxidative Stress in Mice

Comprehensive Physiology, Volume 16, Issue 3, June 2026.
Photobiomodulation (PBM), through its organ‐specific action, exerts beneficial effects on metabolic complications induced by intermittent hypoxia (IH), making it a promising therapeutic strategy for preventing IH‐induced insulin resistance. Graphical abstract created from illustrations provided by BioRender.
Stéphanie Paradis, Britanny Blachot‐Minassian, Sophie Bouyon, Antoine Boutin, Amel Mohamadi, Guillaume Vial, Claire Arnaud, Elise Belaidi   +7 more
wiley   +1 more source

Reoxygenation Mitigates Intermittent Hypoxia-Induced Systemic Inflammation and Gut Microbiota Dysbiosis in High-Fat Diet-Induced Obese Rats

Nature and Science of Sleep
Menglu Dong,1 Xili Liang,1 Tian Zhu,1 Ting Xu,1 Liwei Xie,2,3 Yuan Feng1,4,5 1Sleep Medicine Center, Department of Psychiatric, Nanfang Hospital, Southern Medical University, Guangzhou, People’s Republic of China; 2Guangdong Provincial Key Laboratory of ...
Dong M, Liang X, Zhu T, Xu T, Xie L, Feng Y   +5 more
doaj  

Astaxanthin effect on tissue transglutaminase expression in human neuronal differentiated stem cells exposed to hypoxia and hypoxia/reoxygenation. [PDF]

Sci Rep
Bonaventura G, Iemmolo R, Cognata V, Chiacchio MA, Sebastiano C, Pellitteri R, Campisi A.   +6 more
europepmc   +1 more source

Equol Alleviates Postmenopausal Metabolic Dysfunction‐Associated Steatotic Liver Disease via the GPR30/PI3K Pathway

eFood, Volume 7, Issue 3, June 2026.
This study demonstrates that equol exerts a protective effect on metabolic dysfunction‐associated steatotic liver disease in both in vivo and in vitro by activating the GPR30/PI3K/Nrf2 signaling pathway. Equol's interaction with GPR30 and its ability to activate the PI3K/Nrf2 pathway provide a promising therapeutic strategy for treating metabolic ...
Hanqiang Cui, Bin Wang, Bo Zou, Guiming Zhang, Zhe Xu, Shuo Li, Jing Xu, Xiangmin Ni, Jian Wang   +8 more
wiley   +1 more source

H₂O₂ repurposes plant O₂ sensing to regulate post-hypoxia responses. [PDF]

Nature
Akter S, Perri M, Lavilla-Puerta M, Lichtenauer S, He Y, Shukla V, Carbonare LD, Telara Y, Zhang D, Ferretti B, Gunawardana DM, Myers WK, Barreto P, Giuntoli B, Schwarzländer M, Flashman E, Licausi F.   +16 more
europepmc   +1 more source

Blood Flow Restriction Does Not Impair Single, All‐Out Sprint Cycling Performance

European Journal of Sport Science, Volume 26, Issue 6, June 2026.
ABSTRACT This study examined the effects of sprint duration and blood flow restriction due to cuff pressure applied only during exercise on sprint cycling performance and psychophysiological responses. On separate days, 12 physically active young adults (9 men and 3 women) performed six ‘all‐out’ cycling sprints (5, 10, 15, 20, 25 and 30 s) in a ...
Carlos Dellavechia de Carvalho, Michelle Stein, Siu Nam Li, Mohammed Ihsan, Peter Peeling, Brendan Richard Scott, Marcelo Papoti, Olivier Girard   +7 more
wiley   +1 more source

Establishing a direct interaction between the 19,20-EDP analog SA-22 and SIRT3: impact on cardiac mitochondrial homeostasis. [PDF]

Front Pharmacol
Kranrod JW, Valencia R, Heidari M, Ibrahim KM, Adebesin AM, Munnuri S, Falck JR, Seubert JM.   +7 more
europepmc   +1 more source

Smart Nanodelivery Systems for Immunometabolic Modulation in Osteoarthritis

Exploration, Volume 6, Issue 3, June 2026.
Smart nanodelivery systems deliver therapeutic payloads across the cartilage matrix to ensure their sustained accumulation within chondrocytes at sites of injury. By targeting specific molecular targets and signaling pathways, these platforms modulate the pathological synovium‐cartilage axis to restore immunometabolic homeostasis and drive tissue ...
Qirui Zhao, Zhewen Mi, Shuya Liu, Shijun Liang, Linjia Peng, Zixuan Gao, Jiaming Li, Xiaoqing Lu, Zhiguang Ren, Yongjie Wan, Shengsheng Cui, Longlong Lu, Xiaoyang Gao, Tao Wang, Hui Liang, Furong Tian, de la Fuente Jesus M, Chong Xiang, Luyi Sun, Lichen Xiang, Daxiang Cui   +20 more
wiley   +1 more source

Correction: Dapagliflozin attenuates hypoxia/reoxygenation-caused cardiac dysfunction and oxidative damage through modulation of AMPK. [PDF]

Cell Biosci
Tsai KL, Hsieh PL, Chou WC, Cheng HC, Huang YT, Chan SH.   +5 more
europepmc   +1 more source