Results 101 to 110 of about 25,961 (244)
徐州医科大学学报Objective To investigate the role of μ-opioid receptor (MOR) in Herkinorin-mediated regulation of oxygen-glucose deprivation/reoxygenation (OGD/R) injury in primary rat neurons and its relationship with β-arrestin2.
XU Xin, LIANG Xuan, CUI Xu
doaj +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend The mechanisms underpinning improved maximal oxygen uptake following sprint interval training (SIT) with post‐exercise blood flow restriction (BFR), compared to SIT alone, remain unclear. This study examined the effects of 6 week SIT with (BFR; n = 12) or without (CON; n = 8) post‐exercise BFR on V̇O2peak${{\dot{V}}_{{{{\mathrm{O}
Donald L. Peden +4 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Photobiomodulation restores blood–brain barrier (BBB) integrity following hypoxic stress. A multicellular human BBB model comprising brain microvascular endothelial cells, astrocytes and pericytes was established in a transwell system and subjected to acute hypoxia.
Mirriam Domocos +4 more
wiley +1 more source
Hypoxia Induces a Mitotic Survival Advantage After Radiotherapy in Head and Neck Cancer Cells
International Journal of Cancer, Volume 159, Issue 4, Page 1042-1055, 15 August 2026.Hypoxic tumor environments significantly limit radiotherapy effectiveness against cancer, particularly in head and neck squamous cell carcinoma (HNSCC). Here, the authors tracked hypoxic and post‐hypoxic cells using a hypoxia‐fate mapping system in human papillomavirus (HPV)‐positive and HPV‐negative HNSCC models.
Marilyn Wegge +3 more
wiley +1 more source
Stearoyl-CoA Desaturase-1 Drives Tumor Growth by Interacting With Histone Deacetylase-2 and Deacetylating Nucleophosmin-1. [PDF]
MedComm (2020)Hypoxia induces SCD1 and PLIN2 to drive lipid droplet‐dependent metabolic adaptation in cancer cells. PLIN2 supports survival under stress, whereas SCD1 promotes proliferation upon reoxygenation and remodels the acetylome via HDAC2‐mediated NPM1 deacetylation and destabilization.
Wery C +15 more
europepmc +2 more sources
Freshwater Biology, Volume 71, Issue 7, July 2026.ABSTRACT Growth of ectotherms typically positively correlates with increasing temperature towards an optimal temperature range, followed by a decline in growth when temperatures exceed the optimal temperature range for that organism. When temperature is within or close to the optimal range, food availability and other environmental factors can play ...
Lindsay E. Hansen +4 more
wiley +1 more source
Macrophage Extracellular Traps in Immunity and Cancer
Advanced Science, Volume 13, Issue 35, 24 June 2026.As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li +5 more
wiley +1 more source
Advanced Science, Volume 13, Issue 34, 19 June 2026.ABSTRACT Intestinal ischemia/reperfusion (I/R) injury presents a biphasic pathology: an acute oxidative‐inflammatory phase leading to organ failure, and a recovery phase marked by mucosal dysfunction and bacterial translocation. The developed MPB@TA‐Cu‐Ma nanocomposite functions as a dual‐phase therapeutic platform with significant efficacy. It rapidly
Chenghao Qiu +15 more
wiley +1 more source