Results 41 to 50 of about 57,705 (212)

The effects and potential applications of concentrated growth factor in dentin–pulp complex regeneration

Stem Cell Research & Therapy, 2021
The dentin–pulp complex is essential for the long-term integrity and viability of teeth but it is susceptible to damage caused by external factors. Because traditional approaches for preserving the dentin–pulp complex have various limitations, there is a
Zixia Li, Liu Liu, Liu Wang, Dongzhe Song   +3 more
doaj   +1 more source

Optimized micro‐sized cell sphere‐matrix niche co‐aggregates promote efficient oral and craniomaxillofacial bone regeneration

BMEMat, EarlyView.
The construct of cell‐niche co‐aggregates (GelMA‐SHED sphere‐DDMPs) promotes cranial and periodontal bone regeneration and ensures angiogenic‐osteogenic coupling by downregulating miR‐34c‐5p to enhance the expression of NOTCH1 and its intracellular domain (NICD).
Xiao‐Hui Zhang, Shi‐Han Mu, Yi‐Han Xiao, Lu‐Fan Yang, Peng‐Fei Wang, Teng‐Fei Hu, Jun‐Xi He, Jiong‐Zhen Piao, Sha Zhang, Jin‐Yu Liu, Yi‐De He, Ying‐Ying Wu, Si‐Qi Ying, Xin‐Yue Cai, Chen‐Han Li, Zi‐Qi Zhang, Xiao Lei, Ji Chen, Jian‐Fei Liang, Yan Jin, Bing‐Dong Sui, Chao Ma, Chen‐Xi Zheng, Fang Jin   +23 more
wiley   +1 more source

Orthodentine‐osteodentine and osteocytic‐anosteocytic transition inferred from Silurian stem chondrichthyan dermal jawbones with ever‐white teeth overgrown by brown denticles

Developmental Dynamics, EarlyView.
Abstract Background The dentigerous jawbones of a 423‐million‐year‐old stem chondrichthyan (ischnacanthid acanthodian) carry a characteristic combination of multi‐row non‐shedding white teeth with brownish overgrowing denticles. The color distinction makes it a good model for observing the interaction between two odontode lineages, but the nature of ...
Jia‐Cih Kang, Henning Blom, Tiiu Märss, Donglei Chen   +3 more
wiley   +1 more source

Characterization of Cellular Responses Involved in Reparative Dentinogenesis in Rat Molars [PDF]

, 1995
During primary dentin formation, differentiating primary odontoblasts secrete an organic matrix, consisting principally of type I collagen and non-collagenous proteins, that is capable of mineralizing at its distal front.
Butler, W. T., D'Souza, R. N., Baumgardner, K. R., Litz, M., Bachman, T.   +4 more
core   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source

Traumatic Dental Injuries as a Potential Predisposing Factor for Invasive Cervical Resorption: A Systematic Review

Dental Traumatology, EarlyView.
ABSTRACT Invasive cervical resorption is a clinically challenging and often silent form of external root resorption that may remain undetected until substantial structural damage has occurred. Although traumatic dental injuries are repeatedly cited as potential predisposing factors, the strength, consistency, and clinical meaning of this association ...
Thiago Farias Rocha Lima, Evelin Scarabelli Minchio, Claudia Mendonça Reis Romano, Juliana Machado Barroso Xavier, Francisco Carlos Ribeiro, Liliana Aparecida Pimenta de Barros   +5 more
wiley   +1 more source

The clinical efficacy of anew bioceramic material for indirect pulp capping of deep primary molar caries [PDF]

Kouqiang yixue
Objective To compare the clinical efficacy of a new bioceramic material iRoot BP Plus and a traditional pulp capping material calcium hydroxide for indirect pulp capping of deep primary molar caries.
YU Xuedi, CHEN Qiwen
doaj   +1 more source

Role of osteopontin in the process of pulpal healing following tooth replantation in mice

Regenerative Therapy, 2022
Introduction: The role of osteopontin (OPN) following severe injury remains to be elucidated, especially its relationship with type I collagen (encoded by the Col1a1 gene) secretion by newly-differentiated odontoblast-like cells (OBLCs).
Kiyoko Suzuki-Barrera, Sanako Makishi, Mitsushiro Nakatomi, Kotaro Saito, Hiroko Ida-Yonemochi, Hayato Ohshima   +5 more
doaj   +1 more source

Prevention and Management of Tooth Discolouration of Endodontic Origin (DEO): A State‐of‐the‐Art Review

International Endodontic Journal, EarlyView.
ABSTRACT Background Tooth discolouration of endodontic origin (DEO) refers to an undesirable change in tooth colour arising from the pulp space as a result of reactive physiological processes, pathological processes or endodontic procedures and materials. As DEO frequently affects teeth in the aesthetic zone, it may substantially impair self‐esteem and
Gabriel Krastl, Josette Camilleri, Peter Day, William Nguyen Ha, Mante Kireilyte, Marleen Peumans, Matthias Widbiller, Bill Kahler   +7 more
wiley   +1 more source

The Expression of Neuropeptides in Pulpitis: A Systematic Review and Meta‐Analysis

International Endodontic Journal, EarlyView.
ABSTRACT Background Neuropeptides play key roles in the inflammatory, nociceptive and reparative processes of the dental pulp. Their upregulation has been frequently observed in inflamed pulps, suggesting potential diagnostic value supporting a role for neurogenic inflammation in symptomatic irreversible pulpitis.
N. Watson, D. Edwards, Q. Vuong, I. Obara   +3 more
wiley   +1 more source