Results 61 to 70 of about 57,705 (212)

Platelet‐Rich Fibrins as Local Drug‐Delivery Carriers

Journal of Periodontal Research, EarlyView.
Autologous platelet concentrates (APCs), particularly platelet‐rich fibrin (PRF), act as biologically active fibrin scaffolds, capable of entrapping and gradually releasing therapeutic agents in oral and periodontal therapy. The incorporation of bioactive compounds, such as antibiotics, antifungals, vitamins, antidiabetic drugs, and exosomes, enhances ...
Karim M. Fawzy El‐Sayed, Christof E. Dörfer   +1 more
wiley   +1 more source

Comparison and contrast of bone and dentin in genetic disorder, morphology and regeneration: A review

, 2021
The bone and dentin have distinct healing processes. The healing process of bones is regenerative, as newly formed tissues are morphologically and functionally similar to the original bone structures.
Lee, Gayeong, Ki, Si Hyoung, Park, Joo-Cheol, Chang, Woo Sung, Kim, Jaehyun, Si hyoung Ki, Jaehyun Kim, Woo Sung Chang, Gayeong Lee, Joo-Cheol Park   +9 more
core   +1 more source

The Effects of Rapid Periodontal Distraction on Tooth Vitality and Bone Quality/Quantity: A Split‐Mouth Experimental Design

Orthodontics &Craniofacial Research, EarlyView.
ABSTRACT Objectives Periodontal distraction (PD) osteogenesis is a minimally invasive technique capable of rapidly moving uniradicular teeth, thereby shortening orthodontic treatment time. This study aimed to determine whether: (1) PD‐induced tooth movement affects tooth vitality and (2) the regenerated bone meets restorative standards for implant ...
Parul Sangwan, Ying Liu, Phillip M. Campbell, Michael Ellis, Yan Jing, Peter H. Buschang   +5 more
wiley   +1 more source

Evaluation of Carbonate Apatite Cement in Inducing Formation of Reparative Dentin in Exposed Dental Pulp

, 2017
Carbonate apatite (CO3Ap) cement is a biocompatible material with the ability to induce osteogenesis and is widely studied as the bone substitute material. The similarity of bone to tooth structure in their organic and inorganic composition offers a good
Myrna Nurlatifah Zakaria, Arief Cahyanto, Nisa Fitriani Nurul Pauziah, Indah Puti Sabirin   +3 more
core   +1 more source

Direct Pulp Capping Effect with Experimentally Developed Adhesive Resin Systems Containing Reparative Dentin Promoting Agents on Rat Pulp　-Mixed Amounts of Additives and Their Effect on Wound Healing- [PDF]

, 2011
This study examined the wound healing process of exposed rat pulp when treated with experimental adhesive resin systems. The experimental direct pulp capping adhesive resin systems were composed of primer-I, primer-II and an experimental bonding agent.
Suzuki, Masaya, Yoshihisa Taira, Kato, Chikage, Koichi Shinkai, Masaya Suzuki, Taira, Yoshihisa, Katoh, Yoshiroh, Yoshiroh Katoh, Shinkai, Koichi, Chikage Kato   +9 more
core   +1 more source

Recent Advances in Pulp Capping Materials: An Overview [PDF]

Journal of Clinical and Diagnostic Research, 2014
Emphasis has shifted from the “doomed” organ concept of an exposed pulp to one of hope and recovery. The era of vital-pulp therapy has been greatly enhanced with the introduction of various pulp capping materials. The aim of this article is to summarize
Asma Qureshi, Soujanya E., Nandakumar, Pratapkumar, Sambashivarao   +4 more
doaj   +1 more source

R‐Loops Mediated Odontogenic Differentiation of hDPSCs by Activating the cGAS‐STING Pathway Under Inflammatory Microenvironment

Oral Diseases, EarlyView.
ABSTRACT Background R‐Loops are three‐stranded DNA/RNA hybrids implicated in immune responses. Their role in mesenchymal stem cell differentiation, particularly in dental pulp regeneration under inflammation, remains unclear. Methods Rat pulpo‐dentinal complex (PDC) injury models and LPS‐stimulated human dental pulp stem cells (hDPSCs) were used.
Yun Yang, Yiqing Wang, Yating Miao, Zhipu Luo, Lin Niu, Ruirui Liu   +5 more
wiley   +1 more source

Next-Generation Biomaterials for Vital Pulp Therapy: Exploring Biological Properties and Dentin Regeneration Mechanisms

Bioengineering
The advancement of Vital Pulp Therapy (VPT) in dentistry has shown remarkable progress, with a focus on innovative materials and scaffolds to facilitate reparative dentin formation and tissue regeneration.
Vidhyashree Rajasekar, Mohamed Mahmoud Abdalla, Mengyu Huang, Prasanna Neelakantan, Cynthia Kar Yung Yiu   +4 more
doaj   +1 more source

SVCT2-GLUT1-mediated ascorbic acid transport pathway in rat dental pulp and its effects during wound healing

Scientific Reports, 2023
Ascorbic acid (AA; vitamin C) plays a crucial role in the biosynthesis and secretion of collagen to produce the organic matrix of hard tissues. Nevertheless, the detailed mechanism by which AA induces reparative dentinogenesis is still unknown.
Naoto Ohkura, Kunihiko Yoshiba, Nagako Yoshiba, Naoki Edanami, Hayato Ohshima, Shoji Takenaka, Yuichiro Noiri   +6 more
doaj   +1 more source

Inflammation and mechanical force‐induced bone remodeling

Periodontology 2000, EarlyView.
Abstract Periodontitis arises from imbalanced host–microbe interactions, leading to dysbiosis and destructive inflammation. The host's innate and adaptive immune responses produce pro‐inflammatory mediators that stimulate destructive events, which cause loss of alveolar bone and connective tissue attachment.
Hyeran Helen Jeon, Xin Huang, Leticia Rojas Cortez, Puttipong Sripinun, Jung‐me Lee, Julie J. Hong, Dana T. Graves   +6 more
wiley   +1 more source