Results 61 to 70 of about 861,022 (290)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Muscle oxygenation maintained during repeated-sprints despite inspiratory muscle loading.
PLoS ONE, 2019 A high work of breathing can compromise limb oxygen delivery during sustained high-intensity exercise. However, it is unclear if the same is true for intermittent sprint exercise.
Ramón F Rodriguez +3 more
doaj +1 more source
On the experimental testing of fine Nitinol wires for medical devices [PDF]
, 2011 Nitinol, a nickel titanium alloy, is widely used as a biocompatible metal with applications in high strain medical devices. The alloy exhibits both superelasticity and thermal shape memory behaviour. Basic mechanical properties can be established and are
Dempster, William +2 more
core +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Repeated Loading of Cohesive Soil – Shakedown Theory in Undrained Conditions
Studia Geotechnica et Mechanica, 2015 The development of industry and application of new production techniques could bring about extraordinary problems that have been neglected. One of these challenges in terms of soil mechanics is high frequency cyclic loading.
Głuchowski Andrzej +2 more
doaj +1 more source
On the physical correlations of the thermoplasticity deformation theory [PDF]
, 2012 Розглянуто узагальнення деформаційної теорії термопластичності при неізотермічних процесах навантаження з урахуванням можливого пружного розвантаження після пластичного деформування, повторного пластичного деформування після пружного розвантаження і ...
Holovatyy, B. +3 more
core
Dynamic behavior and damping capacity of auxetic foam pads [PDF]
, 2006 A novel set of auxetic (negative Poisson's ratio) open cell polyurethane foam has been developed and tested under dynamic loading conditions to assess the viscoelastic response under white noise random excitation and compressive cycling.
Bezazi, A +3 more
core +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Structural relaxation in amorphous materials under cyclic tension-compression loading
, 2019 The process of structural relaxation in disordered solids subjected to repeated tension-compression loading is studied using molecular dynamics simulations.
Jana, Pritam Kumar, Priezjev, Nikolai V.
core +1 more source