Results 71 to 80 of about 1,652,346 (296)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Finite Element Analysis of Voided Reinforced Concrete Slabs Enhanced by GFRP Sheets under Monotonic and Repeated Loads

Journal of Engineering
Six (1000*1000 mm2) slab specimens were cast and tested as two-way simply supported slabs previously (three under monotonic loading and three under repeated loading) are used in this research.
Shahad H. Mtashar, Adel A. Al-Azzawi
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Strength of welded joints in class A500C reinforcing bars under low-cycle repeated loads

Будівельні конструкції. Теорія і практика
For more than 25 years now, A500C class reinforcement has been the most widely used in reinforced concrete structures. The introduction of class A500C reinforcement has been accompanied by extensive research into its mechanical properties, bond with ...
Yulii Klymov
doaj   +1 more source

Experimental and modelling buckling of wood-based columns under repeated loading

EPJ Web of Conferences, 2010
Collapse of timber constructions can appear under the effect of load that exceeds the resistance of a carrying element or under the effect of a geometrical instability like buckling.
Nafa Z., Chaplain M., Bouras F.
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Tensile and Tearing Properties of a Geocomposite Mechanically Damaged by Repeated Loading and Abrasion. [PDF]

Materials (Basel), 2023
Carneiro JR, Almeida F, Carvalho F, Lopes ML.   +3 more
europepmc   +1 more source

Steering vector errors and diagonal loading [PDF]

, 2004
Diagonal loading is one of the most widely used and effective methods to improve robustness of adaptive beamformers. In this paper, we consider its application to the case of steering vector errors, i.e.
Besson, Olivier, Vincent, François
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Experimental Research on Breakage Characteristics of Feed Pellets under Different Loading Methods

Agriculture
Particle breakage is a common phenomenon during the processes of production, storage, and transportation. Because of the requirements for pellet integrity in poultry farming, research on the breakage characteristics of feed pellets is necessary.
Xianrui Kong, Qing Cao, Zhiyou Niu
doaj   +1 more source