Results 221 to 230 of about 201,272 (267)
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Reperfusion therapy for stroke
Australian and New Zealand Journal of Medicine, 1999AbstractStroke is a heterogenous disease, but about 85% of strokes are as a result of cerebral ischaemia due to arterial occlusion. It seems logical to assume that, as in myocardial infarction, treatment designed to dissolve clots should be helpful.We now have a substantial amount of data on the use of aspirin, heparin and thrombolytic drugs in the ...
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New England Journal of Medicine, 2007
Lethal reperfusion injury is a paradoxical type of myocardial injury caused by the restoration of coronary blood flow after an ischemic episode. This review focuses on the mechanisms of the injury, on attempts to protect the heart against it, and on promising new approaches to cardioprotection during percutaneous coronary intervention.
Derek M, Yellon, Derek J, Hausenloy
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Lethal reperfusion injury is a paradoxical type of myocardial injury caused by the restoration of coronary blood flow after an ischemic episode. This review focuses on the mechanisms of the injury, on attempts to protect the heart against it, and on promising new approaches to cardioprotection during percutaneous coronary intervention.
Derek M, Yellon, Derek J, Hausenloy
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Postischemic reperfusion and “reperfusion paradox” in ischemic stroke
S.S. Korsakov Journal of Neurology and PsychiatryCurrent therapeutic approaches for the acute phase of ischemic stroke (IS) primarily involve advanced reperfusion technologies aimed at restoring blood flow to areas with reduced perfusion. However, even with successful restoration of blood flow through the affected vessel, reperfusion injury can intensify tissue damage by exacerbating metabolic ...
S.A. Ikonnikova +3 more
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PathophysioSogy of Myocardial Reperfusion
Cardiology Clinics, 1987The feasibility of myocardial reperfusion is established. However, restoring patency to epicardial coronary arteries does not necessarily signify restoration of tissue perfusion or restoration of biochemical or mechanical function to the heart muscle previously supplied by the occluded vessel.
K A, Fox, J E, Saffitz, P B, Corr
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Pathophysiology of reperfusion injury
2011INTRODUCTION Ischaemia-Reperfusion Injury (IRI) is defined as the paradoxical exacerbation of cellular dysfunction and death, following restoration of blood flow to previously ischaemic tissues. Reestablishment of blood flow is essential to salvage ischaemic tissues.
Cowled, P., Fitridge, R.
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Critical Care Nursing Clinics of North America, 1990
A review of the mechanism of ischemic-reperfusion injury, proposed interventions to prevent injury, and future directions have been presented to enhance the practitioner's knowledge of this new, exciting concept in myocardial injury. There is increasing evidence in the literature that reperfusion injury may occur in other organ systems and is ...
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A review of the mechanism of ischemic-reperfusion injury, proposed interventions to prevent injury, and future directions have been presented to enhance the practitioner's knowledge of this new, exciting concept in myocardial injury. There is increasing evidence in the literature that reperfusion injury may occur in other organ systems and is ...
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Cytokines and reperfusion injury
Neurology, 1997There is increasing evidence that the inflammatory response plays an important role in the potentiation of central nervous system (CNS) ischemic injury. Much of this inflammatory response appears to be mediated by interleukins (IL), a multifunctional subclass of cytokines.
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Controlled Reperfusion Against Ischemia Reperfusion Injury
2018Recanalization and reperfusion after an ischemic stroke sometimes could be harmful and deadly, and controlled perfusion may be a potential solution. This article summarized controlled perfusion literature, both animal and clinical, on heart, lung, kidney, and limbs and compared with brain controlled perfusion.
Weijian Jiang +3 more
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Cytokines and Reperfusion Injury
Journal of Cardiac Surgery, 1993Myocardial dysfunction following prolonged ischemia and reperfusion is at least partially dependent upon adhesion of neutrophils to myocardial and endothelial cells. Neutrophils are thought to contribute to reperfusion injury by two mechanisms: impairment of the microvasculature by physical obstruction, and secretion of products that damage ...
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