Results 241 to 250 of about 382,913 (294)

Oxycodone: A Pain-Relieving Agent With Cardioprotective Properties Against Myocardial Ischemia-Reperfusion Injury. [PDF]

Cardiovasc Ther
Firoozabadi MD, Nooralishahi B, Rezaei-Tazangi F.   +2 more
europepmc   +1 more source

Hypoxia‐Induced Histone Lactylation Promotes Ferroptosis in Cardiomyocytes via the Wnt/β‐Catenin Pathway

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study investigated the effects of histone lactylation on ferroptosis in hypoxia‐induced cardiomyocytes. A hypoxia model was established in AC16 cells treated with 2‐Deoxy‐D‐glucose (2‐DG, a glucose analogue), ferrostatin‐1 (Fer‐1, a selective ferroptosis inhibitor), lactate (LA), sh‐β‐catenin (shRNA of β‐catenin), or SKL2001 (an agonist ...
Xin‐Hua Zhu, Jing‐Wen Hou, Zhong‐Ying Lv, Ming‐Hui Sun, Xiao‐Yang Zhang, Lei Zhang, Mei Wang   +6 more
wiley   +1 more source

Integrated analysis and validation of metabolism-related genes in lung transplantation-induced cold ischemia/ reperfusion injury. [PDF]

PeerJ
Zhu L, Ding J, Wei D, Chen J.
europepmc   +1 more source

Sacubitril/Valsartan Ameliorates Inflammation and Oxidative Stress in Hypertensive Heart Disease by Upregulating CAMKK2 Protein and Modulating the AMPK/AKT/GSK‐3β Axis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Sacubitril/valsartan (Sac/Val) has emerged as an effective compound with myocardium‐protective functions in experimental and clinical trials for heart failure. This study investigated the function of Sac/Val in hypertensive heart disease (HHD) and explored the underlying mechanism.
Yan‐Jun Yang, Jiu‐Sheng Li
wiley   +1 more source

Melatonin and mitochondrial protection in cardiac ischemia-reperfusion injury: mechanisms, evidence and translational perspectives. [PDF]

Basic Res Cardiol
Pedriali G, Leo S, Tiezzi M, Colarusso EN, Morciano G, Tremoli E, Pinton P.   +6 more
europepmc   +1 more source

TET3‐Mediated m5C Modification of CCAT2 Accelerates Cardiac Microvascular Endothelial Cell Damage in Acute Coronary Syndrome

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Acute coronary syndrome (ACS) is a clinical syndrome involving myocardial ischemia. This study aimed to elucidate the mechanism of TET3 in ACS‐induced CMEC damage, thereby identifying a new target for ACS treatment. The expression of TET3 in ACS patients and healthy subjects was analyzed.
Jun‐Cheng Liu, Wen‐Juan Wang, Ting‐Ting Zhang, Qi‐Chong Yang, Haliminai Dilimulati, Song‐Tao An   +5 more
wiley   +1 more source

Ischaemia-reperfusion dynamics in acute myocardial infarction experimental swine model: new insights from quantitative CMR. [PDF]

Eur Heart J Imaging Methods Pract
Viallon M, Petrusca L, Duchateau N, Augeul L, Ovize M, Mewton N, Croisille P.   +6 more
europepmc   +1 more source

Reducing mitochondrial dysfunction through combination therapy to limit ischemia-reperfusion injury in male DCD rats. [PDF]

Front Cardiovasc Med
Kiernan Z, Labate G, Chen Q, Quader M.
europepmc   +1 more source

Disrupted SR-Mitochondria Coupling Drives Ischemia-Reperfusion Vulnerability in the Middle-Aged Rat Heart. [PDF]

Biomedicines
Leskova Majdova K, Bencurova M, Kovalska M, Kaplan P, Racay P, Tatarkova Z.   +5 more
europepmc   +1 more source

Chest pain with elevated ST segment in lead V1: a case report. [PDF]

Front Cardiovasc Med
He Z, Pu X, Zeng L.
europepmc   +1 more source