Results 81 to 90 of about 382,913 (294)

Coacervates Made of Elastin‐Like Polypeptides Fused with Melanocyte‐Stimulating Hormone and Monocyte Chemoattractant Protein Enhance Skin Wound Healing in Spinal Cord‐Injured Mice

Advanced Healthcare Materials, EarlyView.
Pressure skin wounds are frequent complications after spinal cord injury (SCI), with impaired healing due to vascular and immune deficits. Elastin‐like polypeptides (ELP) fused to α‐MSH (MSH‐ELP) or MCP‐1 (MCP‐ELP) are developed and tested on these wounds. The resulting nanoparticles are non‐toxic and bioactive, and they enhance macrophage recruitment,
Suneel Kumar, Dhruv Patel, Greeshma Manjunath, Shashank Madhavan, Ashley Mathew, Dnyaneshwari Rananavare, Jahnavi Shah, Francois Berthiaume   +7 more
wiley   +1 more source

Gut microbiota-derived gamma-aminobutyric acid from metformin treatment reduces hepatic ischemia/reperfusion injury through inhibiting ferroptosis

eLife
Hepatic ischemia/reperfusion injury (HIRI) is a common and inevitable factor leading to poor prognosis in various liver diseases, making the outcomes of current treatments in clinic unsatisfactory.
Fangyan Wang, Xiujie Liu, Furong Huang, Yan Zhou, Xinyu Wang, Zhengyang Song, Sisi Wang, Xiaoting Wang, Dibang Shi, Gaoyi Ruan, Xiawei Ji, Eryao Zhang, Zenglin Tan, Yuqing Ye, Chuang Wang, Jesse Zhu, Wantie Wang   +16 more
doaj   +1 more source

Modulation of Mitochondrial Bioenergetics in the Isolated Guinea Pig Beating Heart by Potassium and Lidocaine Cardioplegia: Implications for Cardioprotection [PDF]

, 2009
Mitochondria are damaged by cardiac ischemia/reperfusion (I/R) injury but can contribute to cardioprotection. We tested if hyperkalemic cardioplegia (CP) and lidocaine (LID) differently modulate mitochondrial (m) bioenergetics and protect hearts against ...
Aldakkak, Mohammed, Camara, Amadou K.S., Chen, Qun, Heisner, James S., Lesnefsky, Edward J., Stowe, David F.   +5 more
core   +2 more sources

Smart Catheters for Diagnosis, Monitoring, and Therapy

Advanced Healthcare Materials, EarlyView.
This study presents a comprehensive review of smart catheters, an emerging class of medical devices that integrate embedded sensors, robotics, and communication systems, offering increased functionality and complexity to enable real‐time health monitoring, diagnostics, and treatment. Abstract This review explores smart catheters as an emerging class of
Azra Yaprak Tarman, Samiha Ahmed, Majed Othman Althumayri, Megan Guy, Darlenne Chavez Lugo, Frances S. Ligler, George T. Ligler, Rahmi Oklu, Hiroshi Kawahira, Michael J. McShane, Jun Kameoka, Jonathan Bova, Hatice Ceylan Koydemir   +12 more
wiley   +1 more source

Early Coronary Reperfusion Facilitates Return of Spontaneous Circulation and Improves Cardiovascular Outcomes After Ischemic Cardiac Arrest and Extracorporeal Resuscitation in Pigs

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
Background Extracorporeal cardiopulmonary resuscitation (ECPR) is widely proposed for the treatment of refractory cardiac arrest. It should be associated with coronary angiography if coronary artery disease is suspected.
Alice Hutin, Lionel Lamhaut, Fanny Lidouren, Matthias Kohlhauer, Nicolas Mongardon, Pierre Carli, Alain Berdeaux, Bijan Ghaleh, Renaud Tissier   +8 more
doaj   +1 more source

Monitoring of lung edema by microwave reflectometry during lung ischemia-reperfusion injury in vivo [PDF]

, 2006
It is still unclear whether lung edema can be monitored by microwave reflectometry and whether the measured changes in lung dry matter content (DMC) are accompanied by changes in PaO(2) and in pro-to anti-inflammatory cytokine expression (IFN-gamma and ...
Blades B, Bland JM, D'Armini AM, Date H, DeMeo DL, Eppinger M, Eppinger MJ, Fein A, Fonkalsrud EW, Kaatze U, Kai Nowak, Kondo Y, Martha Maria Gebhard, Matsuda S, Michael Schaefer, Miura N, Nierman DM, Palazzo R, Peter Hohenberger, Rigaud B, Roman Patrick Metzger, Schaefer M, Schaefer M, Schaefer M, Stefan Post, Trulock EP, Van Raemdonck DE, West JB, Wichert PV, Wolfgang Gross, Yamazaki F   +30 more
core   +1 more source

Bioengineered 3D hPSC‐Cholangiocyte Ducts With Physiological Signals for Biliary Disease Modeling

Advanced Healthcare Materials, EarlyView.
Tian and colleagues generated a bioengineered bile duct from human pluripotent stem cell (hPSC)‐derived intrahepatic cholangiocytes within a high‐throughput, 384‐well platform to systematically examine the influence of biliary physiological signals including fluid flow, stromal cells and bile acids, and models intrahepatic biliary disease progression ...
Britney Tian, Mina Ogawa, Manami Kondo, Gabrielle Langeveld, Ling Jun Huan, Feng Zhang, Andrew Hollinger, Sara Deir, Christine Bear, Boyang Zhang, Shinichiro Ogawa   +10 more
wiley   +1 more source

Evaluating the efficacy of smoke management technologies in laparoscopic sleeve gastrectomy: insights from a prospective, single-centre comparative study

Scientific Reports
Surgical power devices generate surgical smoke that may contain infectious components. Various technologies have been developed to improve surgical smoke management, but comparative performance data from human studies are limited.
Cédric R. D. Demtröder, Daniel Göhler, Kathrin Oelschlägel, Claudia Jahn-Wolf, Hülya Agarius, Peter Kirchmeyer, Fabian Kockelmann, Sébastien Roger, Mehdi Ouaissi, Dmitrij Dajchin, Urs Giger-Pabst   +10 more
doaj   +1 more source

Electrocardiographic manifestation of cardiac repolarization dispersion [PDF]

, 2019
Alterations of repolarization heterogeneity in the heart have been established as anAlterations of repolarization heterogeneity in the heart have been established as ...
Sedova Ksenia
core  

Endothelial preconditioning by transient oxidative stress reduces inflammatory responses of cultured endothelial cells to TNF-α [PDF]

, 2000
Brief episodes of ischemia can render an organ resistant to subsequent severe ischemia. This ‘ischemic preconditioning’ is ascribed to various mechanisms, including oxidative stress. We investigated whether preconditioning exists on an endothelial level.
Akimitsu T., BERNHARD F. BECKER, CHRISTIAN KUPATT, DeFily D. V., Hearse D. J., Hoshida S., Jerome S. N., Schreck R., Schulz R., Siegfried M. R., STEFAN ZAHLER, Yao Z.   +11 more
core   +1 more source