Results 71 to 80 of about 267,492 (314)

The uncoordinated-5 homolog B receptor affects hepatic ischemia reperfusion injury [PDF]

, 2012
Recent evidence has demonstrated additional roles for the neuronal guidance protein receptor UNC5B outside the nervous system. Given the fact that ischemia reperfusion injury (IRI) of the liver is a common source of liver dysfunction and the role of ...
Tiago Granja (147967), Tiago Granja, David Köhler (147965), Rosenberger, Peter, Klemens König, Carla Jennewein (147970), König, Klemens, Valbona Mirakaj, Mirakaj, Valbona, Tran, Thi Hoai Nguyen, Granja, Tiago, Nguyen Tran, Valbona Mirakaj (147976), Kröhnert, Friedemann, Peter Rosenberger, Nguyen Tran (147973), Klemens König (147961), Jennewein, Carla, Tran, Nguyen, Peter Rosenberger (37609), Carla Jennewein, Köhler, David, David Köhler, Friedemann Kröhnert, Friedemann Kröhnert (147979)   +24 more
core   +1 more source

Testing and Simulation of Multilayer Polyvinylidene Fluoride‐Based Piezoelectric Energy Harvester Devices

Advanced Materials Technologies, EarlyView.
The study considers the use of polymer/dielectric‐based multilayers piezoelectric Energy Harvesters (EH) to produce an output voltage and current, by exploiting the mechanical energy provided by human organs movements. In particular, the heart motion is considered from the kinematic viewpoint, and a multiphysics theoretical model is developed to assess
Hamdi Ezzin, Silvia Monchetti, Paolo Emilio Puddu, Luciano Teresi, Antonio DeSimone, Roberto Brighenti   +5 more
wiley   +1 more source

KATP channels and cardioprotection [PDF]

Arhiv za farmaciju
This review discusses ATP-sensitive potassium (KATP) channels, which connect intracellular energy metabolism to cellular electrical activity and play crucial roles in various physiological processes, particularly in the pancreas and cardiovascular system.
Taskin Eylem, Samper Natalie, Yang Hua-Qian, Nakamura Tomoe Y., Ramasamy Ravichandran, Coetzee William A.   +5 more
doaj   +1 more source

Intravenous sphingosylphosphorylcholine protects ischemic and postischemic myocardial tissue in a mouse model of myocardial ischemia/reperfusion injury [PDF]

, 2010
HDL, through sphingosine-1-phosphate (S1P), exerts direct cardioprotective effects on ischemic myocardium. It remains unclear whether other HDL-associated sphingophospholipids have similar effects.
Bodo Levkau, Levkau, Bodo, Herrgott, Ilka, Johanning, Kai, Echtermeyer, Frank, Chun, Jerold, Hildebrand, Reinhard, Ilka Herrgott, Gregor Theilmeier, Christine Herzog, Winterhalter, Michael, Frank Ulrich Müller, Schmitz, Martina, Müller, Frank Ulrich, Jan Mersmann, Michael Winterhalter, Reinhard Hildebrand, Martina Schmitz, Herzog, Christine, Frank Echtermeyer, Jerold Chun, Theilmeier, Gregor, Mersmann, Jan, Larmann, Jan, Jan Larmann, Kai Johanning   +25 more
core   +1 more source

Magnetic Micro‐ and Nanorobots for Precision Thrombolysis: Design Strategies and Translational Challenges

Advanced Robotics Research, EarlyView.
Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin, Yimo Yan, Nikola Cesarovic, Simone Schuerle   +3 more
wiley   +1 more source

Role of purinoreceptors in the release of extracellular vesicles and consequences on immune response and cancer progression

Biomedical Journal
Cell-to-cell communication is a major process for accommodating cell functioning to changes in the environments and to preserve tissue and organism homeostasis.
Thomas Duret, Mohammed Elmallah, Jérôme Rollin, Philippe Gatault, Lin-Hua Jiang, Sébastien Roger   +5 more
doaj   +1 more source

A 3D In Vitro Model of the Human Hepatobiliary Junction

Advanced Science, EarlyView.
A 3D human organoid platform reconstructs the hepatobiliary junction between primary adult hepatocytes and intrahepatic cholangiocytes. These adult hepatobiliary organoids (aHBOs) support directional bile transport from canaliculi to ductule‐like structures, enable quantitative imaging of junction dynamics, and reveal cell‐type‐specific vulnerabilities
Ashley D. Westerfield, Katarzyna A. Grzelak, Katie Katsuyama, Vardhman Kumar, Bess M. Miller, Joa Yun, Jesse Kirkpatrick, David Mankus, Margaret E. Bisher, Abigail K.R. Lytton‐Jean, Z. Gordon Jiang, David D. Lee, Christopher S. Chen, Sangeeta N. Bhatia   +13 more
wiley   +1 more source

Deguelin attenuates reperfusion injury and improves outcome after orthotopic lung transplantation in the rat

, 2012
The main goal of adequate organ preservation is to avoid further cellular metabolism during the phase of ischemia. However, modern preservation solutions do rarely achieve this target.
Paulus, Patrick, Tacke Sabine, Johannes Holfeld, Karnowski Nora, Patrick Paulus, Holfeld, Johannes, Urbschat, Anja, Urbschat Anja, Zacharowski, Kai, Tacke, Sabine, Ockelmann, Pia, Nora Karnowski, Karnowski, Nora, Bertram Scheller, Scheller, Bertram, Pia Ockelmann, Ellinghaus, Peter, Paulus Patrick, Zacharowski Kai, Sabine Tacke, Ellinghaus Peter, Anja Urbschat, Kai Zacharowski, Peter Ellinghaus, Ockelmann Pia, Scheller Bertram, Holfeld Johannes   +26 more
core   +1 more source

CD4+ Tregs Drive Post‐Ischemic Sprouting Angiogenesis via Endothelial YY1/MAML1 Reactivation

Advanced Science, EarlyView.
ABSTRACT Microvascular complications of diabetes are chronic diseases of small vessels. We previously found that CD4+ regulatory T‐cells (Tregs) are markedly reduced in type 2 diabetes (T2D) after ischemic injury in both mice and humans, and that Treg deficiency in immunodeficient mice impairs vascular regeneration.
Hang Qu, Cheng Kiu Ho, Jitao Liu, Lei Cui, Yangfeng Hou, Cai Liang, Wenchu Ye, Randolph H. L. Wong, Shohei Hori, Bin Zhou, Kathy O. Lui   +10 more
wiley   +1 more source

Recalibrating Reperfusion Waypoints [PDF]

Circulation, 2017
Article, see p 1462 > There falls a shadow, as T. S. Eliot noted, between the conception and the creation. In the annals of innovation, new ideas are only part of the equation. Execution is just as important . > > —Walter Isaacson ( Steve Jobs , p.
Paul W, Armstrong, Robert C, Welsh
openaire   +2 more sources