Results 111 to 120 of about 199,564 (290)

Author Correction: A mosquito lipoxin/lipocalin complex mediates innate immune priming in Anopheles gambiae

open access: yesNature Communications, 2023
Jose Luis Ramirez   +7 more
doaj   +1 more source

Pirin Transcriptionally Regulates PLA2G4A To Inhibit Ferroptosis in Colorectal Cancer via Lipid Profile Remodeling

open access: yesAdvanced Science, EarlyView.
This study identifies Pirin (PIR), an iron‐binding protein, as a critical ferroptosis suppressor in colorectal cancer through lipid membrane remodeling. PIR, induced by NRF2 during ferroptotic stress, transcriptionally regulates PLA2G4A to shift cellular lipid composition away from ferroptosis‐permissive polyunsaturated phospholipids.
Wei Shi   +10 more
wiley   +1 more source

Neuroprotective potential for mitigating ischemia-reperfusion-induced damage

open access: yesNeural Regeneration Research
Reperfusion following cerebral ischemia causes both structural and functional damage to brain tissue and could aggravate a patient’s condition; this phenomenon is known as cerebral ischemia-reperfusion injury.
Zi Ye   +8 more
doaj   +1 more source

HUWE1 in Skeletal Muscle Prevents Muscle Fatigue via Maintaining Iron and Calcium Homeostasis

open access: yesAdvanced Science, EarlyView.
This study investigates the impact of iron homeostasis on exercise. Loss of the HECT domain‐containing ubiquitin ligase E3 (HUWE1) in skeletal muscle restrains the exercise performance in mice with downregulated ferroportin expression leading to iron overload, which is ameliorated by dietary iron restriction.
Huike Jiao   +10 more
wiley   +1 more source

Role of tubular cell-derived exosomes in renal ischemia reperfusion injury

open access: yesLinchuang shenzangbing zazhi
Renal ischemia reperfusion injury refers to a pathophysiological phenomenon that aggravates the degree of renal injury due to the restoration of blood supply after transient ischemia of renal tissue.
Jin-zhu Huang   +7 more
doaj   +1 more source

Prophylactic Treatment with Cerium Oxide Nanoparticles Attenuate Hepatic Ischemia Reperfusion Injury in Sprague Dawley Rats

open access: gold, 2017
Nandini D.P.K. Manne   +8 more
openalex   +1 more source

Mitochondrial Adaptation to Mechanical Stress in Cardiac Ageing and Disease

open access: yesAdvanced Science, EarlyView.
Mechanical forces shape the heart's energy factories. This review explores how mitochondria in cardiac cells sense and respond to biomechanical stress, altering their structure, positioning, and metabolism. By linking mechanical cues to mitochondrial adaptation, the article highlights pathways driving heart disease and points to new strategies for ...
Aishwarya Prakash, Thomas Iskratsch
wiley   +1 more source

Endotoxin tolerance protects against local hepatic ischemia/reperfusion injury in the rat [PDF]

open access: bronze, 2000
Emilio Domínguez Fernández   +6 more
openalex   +1 more source

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