Results 191 to 200 of about 2,074,884 (292)

12‐HETE Is an Endogenous Modulator of BLT2 Triggering Vascular Degeneration, Dissection, and Rupture

Advanced Science, EarlyView.
In thoracic aortic dissection (TAD), elevated levels of the arachidonic acid metabolite 12‐HETE, produced by macrophage‐specific 12/15‐lipoxygenase (12/15‐LOX), bind to the BLT2 receptor on vascular cells. This activates the NOX‐1/ROS/NF‐κB signaling pathway, leading to IL‐6 release.
Yuyu Li, Jiaqi Yu, Weiyao Chen, Xue Wang, Xin Tan, Jing Cui, Yihao Wang, Xuan Xu, Rui Lin, Zhengkai Wang, Wenxi Jiang, Yongliang Zhong, Jie Du, Yuan Wang   +13 more
wiley   +1 more source

Argon: a novel therapeutic option to treat neuronal ischemia and reperfusion injuries?

, 2015
Ulrich Goebel, F Ulbrich
openalex   +1 more source

The Pomace Extract Taurisolo Protects Rat Brain From Ischemia-Reperfusion Injury

, 2020
Dominga Lapi, Mariano Stornaiuolo, Lina Sabatino, Eduardo Sommella, Gian Carlo Tenore, Maria Daglia, Rossana Scuri, Martina Di Maro, A. Colantuoni, Ettore Novellino   +9 more
openalex   +1 more source

Neuroprotective Nanoplatform Integrating Antioxidant MXene Nanozymes and Ferroptosis Inhibitors for Targeted Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
Cerebral ischemia‐reperfusion injury (CIRI) is a key pathological process limiting the efficacy of stroke therapy. This study has developed an innovative, multifunctional, brain‐targeted nanoplatform (RFP) containing MXene nanoenzymes and ferroptosis inhibitors.
Lu Wang, Chao Hou, Shuo Li, Lizhi Yang, Yiqun Lin, Sen Wang, Xiaohua Jia, Hui Hui, Wen He, Wei Zhang   +9 more
wiley   +1 more source

Prevention of cold ischaemia-reperfusion injury by an endothelin receptor antagonist in experimental renal transplantation [PDF]

, 1999
I. Herrero
openalex   +1 more source

FGF18 alleviates hepatic ischemia-reperfusion injury via the USP16-mediated KEAP1/Nrf2 signaling pathway [PDF]

, 2022
Weitao Cong, Gaozan Tong, Yi‐Ming Chen, Xixi Chen, Junfu Fan, Kunxuan Zhu, Zijing Hu, Santie Li, Junjie Zhu, jianjun feng, zhaohang wu, Zhenyu Hu, Bin Zhou, Litai Jin, Jingling Shen, Xiaokun Li   +15 more
openalex   +1 more source

HUWE1 in Skeletal Muscle Prevents Muscle Fatigue via Maintaining Iron and Calcium Homeostasis

Advanced Science, EarlyView.
This study investigates the impact of iron homeostasis on exercise. Loss of the HECT domain‐containing ubiquitin ligase E3 (HUWE1) in skeletal muscle restrains the exercise performance in mice with downregulated ferroportin expression leading to iron overload, which is ameliorated by dietary iron restriction.
Huike Jiao, Yuting Du, Danxia Zhou, Meng Bai, Xu Gao, Zhenyue Hao, Nan‐Jie Xu, Jiaqiang Liu, Ying Huang, Zhenji Gan, Jing Zhang   +10 more
wiley   +1 more source

THE ROLE OF CELLULAR STRESS DURING COLD ISCHAEMIC AND REPERFUSION INJURY

, 2002
Jonathan R Roberts
openalex   +2 more sources

Nebulized synthetic surfactant in reperfusion injury after single lung transplantation [PDF]

, 1995
Martin Strüber, Joachim Cremer, Wolfgang Harringer, Stephan Hirt, Angelika Costard‐Jäckle, Axel Haverich   +5 more
openalex   +1 more source

Kv7-channel Blockage Reduces Liver Ischemia-reperfusion Injury in Mice [PDF]

, 2023
Johanna Ollesky, Marcella Steffani, Carolin Mogler, Fabian Stöcker, Volker Aßfalg, Helmut Frieß, Norbert Hüser, Daniel Hartmann   +7 more
openalex   +1 more source