Results 171 to 180 of about 1,153,543 (306)

Curcumin in ischemia-reperfusion injury across multiple organs: A review. [PDF]

J Int Med Res
Lu J, Fang X, Wei X, Xu X.
europepmc   +1 more source

The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding

Animal Research and One Health, EarlyView.
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang, Weiran Wu, Qingqing Cai, Jiaxing Wang, Qi Gao, Muhammad Iftikhar, Yulin Bi, Hao Bai, Lihong Gu, Guobin Chang, Shihao Chen   +10 more
wiley   +1 more source

Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm, Lyn D. Ferguson, Iain B. McInnes   +2 more
wiley   +1 more source

Neutrophil-mediated myocardial ischemia-reperfusion injury: mechanisms and potential therapeutic targets. [PDF]

Front Immunol
Xu W, Zhang Z, Wei Y, Zhou Z, Guo J.
europepmc   +1 more source

IgG Glycosylation‐Dependent CLEC7A Signaling Drives Podocyte Dysfunction in Lupus Nephritis

Arthritis &Rheumatology, EarlyView.
Objective Lupus nephritis (LN) is a severe complication of systemic lupus erythematosus (SLE) that can lead to end‐stage kidney disease and increased mortality. IgG from patients with LN displays abnormal glycosylation, contributing to podocyte injury.
Rohit Upadhyay, Alexia Orellana, George C. Tsokos, Rhea Bhargava   +3 more
wiley   +1 more source

Cognitive impairment after cerebral ischemia-reperfusion injury: a neuroecosystem perspective. [PDF]

Front Neurol
Xie J, Zhang T, Zhang J, Zhang L, Huang T, Bi W, Zhao M.   +6 more
europepmc   +1 more source

Triptolide attenuates cerebral ischemia and reperfusion injury in rats through the inhibition the nuclear factor kappa B signaling pathway

, 2015
Xiao-Qing Jin,1,2 Fei Ye,1 Jun-Jian Zhang,1 Yan Zhao,2 Xian-Long Zhou2 1Department of Neurology, 2Emergency Center, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, People’s Republic of China Abstract: Inflammation plays critical roles in the
Zhang JJ, Jin XQ, Zhou XL, Ye F, Zhao Y
core  

Possible therapeutic repositioning of valproic acid: From epileptic seizures to acute kidney injury

British Journal of Clinical Pharmacology, EarlyView.
Valproic acid, an anticonvulsant, may be repositioned to prevent acute kidney injury due to ischemia followed by reperfusion. It preserves renal functions, electrolyte homeostasis and active sodium transport in kidney tubules, and blocks the onset of hypertension.
Danilo Alves‐Bezerra, Luiza B. Negreiros, Amaury Pereira‐Acácio, Isadora G. Almeida, João P. M. Veloso‐Santos, Jarlene A. Lopes, Glória Costa‐Sarmento, Humberto Muzi‐Filho, Adalberto Vieyra   +8 more
wiley   +1 more source

Pharmacological strategies for intestinal ischemia-reperfusion injury: mechanisms and therapeutic advances. [PDF]

Front Pharmacol
Wang W, Ma J, Wen Y, Liu J.
europepmc   +1 more source

Effects of μ-Agatoxin-Aa1a in Cellular and Rat Models of Myocardial Ischemia-Reperfusion Injury. [PDF]

Int J Mol Sci
Iurova E, Dolgova D, Mikheeva N, Ermakova A, Sugak D, Gilmutdinova A, Fomin A, Saenko Y.   +7 more
europepmc   +1 more source