Results 261 to 270 of about 2,272,622 (291)
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Pathophysiology of reperfusion injury
2011INTRODUCTION Ischaemia-Reperfusion Injury (IRI) is defined as the paradoxical exacerbation of cellular dysfunction and death, following restoration of blood flow to previously ischaemic tissues. Reestablishment of blood flow is essential to salvage ischaemic tissues.
Cowled, P., Fitridge, R.
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Journal of Cardiovascular Pharmacology, 2019
Background: Activation of the NLRP3 inflammasome is a primary driver of sterile inflammation in response to myocardial ischemia reperfusion. Pharmacologic inhibitors of the NLRP3 inflammasome are being developed.
S. Toldo +8 more
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Background: Activation of the NLRP3 inflammasome is a primary driver of sterile inflammation in response to myocardial ischemia reperfusion. Pharmacologic inhibitors of the NLRP3 inflammasome are being developed.
S. Toldo +8 more
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Cytokines and Reperfusion Injury
Journal of Cardiac Surgery, 1993Myocardial dysfunction following prolonged ischemia and reperfusion is at least partially dependent upon adhesion of neutrophils to myocardial and endothelial cells. Neutrophils are thought to contribute to reperfusion injury by two mechanisms: impairment of the microvasculature by physical obstruction, and secretion of products that damage ...
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Cytokines and reperfusion injury
Neurology, 1997There is increasing evidence that the inflammatory response plays an important role in the potentiation of central nervous system (CNS) ischemic injury. Much of this inflammatory response appears to be mediated by interleukins (IL), a multifunctional subclass of cytokines.
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Journal of Cellular Physiology, 2019
Autophagy is the general term of lysosomal degradation of substances in cells, which is considered the key to maintaining the normal structure and function of the heart.
Binhao Shi +4 more
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Autophagy is the general term of lysosomal degradation of substances in cells, which is considered the key to maintaining the normal structure and function of the heart.
Binhao Shi +4 more
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Renal Perfusion/Reperfusion Injuries
Journal of Urology, 1988Apres un rappel sur la physiologie renale de la perturbation de la perfusion, on etudie la biologie cellulaire de la lesion renale ischemique, les perturbations hormonales au cours de l'ischemie renale, la prevention et le traitement de l'insuffisance renale aigue ...
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Cell Death Mechanisms in Cerebral Ischemia–Reperfusion Injury
Neurochemical Research, 2022Qian-ru Zhang +4 more
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New horizons (Baltimore, Md.), 1996
Reperfusion injury, precipitated by lack of oxygen, is likely to play a major role in many clinical conditions, including shock, coronary artery occlusion disease, and solid organ transplantation. Certain tissues, such as the intestinal mucosa, may be especially susceptible because of the specific microvascular anatomy.
A, Ar'Rajab, I, Dawidson, R, Fabia
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Reperfusion injury, precipitated by lack of oxygen, is likely to play a major role in many clinical conditions, including shock, coronary artery occlusion disease, and solid organ transplantation. Certain tissues, such as the intestinal mucosa, may be especially susceptible because of the specific microvascular anatomy.
A, Ar'Rajab, I, Dawidson, R, Fabia
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Controlled Reperfusion Against Ischemia Reperfusion Injury
2018Recanalization and reperfusion after an ischemic stroke sometimes could be harmful and deadly, and controlled perfusion may be a potential solution. This article summarized controlled perfusion literature, both animal and clinical, on heart, lung, kidney, and limbs and compared with brain controlled perfusion.
Weijian Jiang +3 more
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Myocardial ischaemia–reperfusion injury and cardioprotection in perspective
Nature Reviews Cardiology, 2020G. Heusch
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