Results 261 to 270 of about 339,218 (339)

VAMP4 in hypoxic adipose stem cell exosomes alleviates ischemia-reperfusion injury. [PDF]

Cell Mol Life Sci
Wang Y, Yu S, Wang X, Jin R, Liu F, Yang J.   +5 more
europepmc   +1 more source

Ketogenic diet for infantile epileptic spasms

Epilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury, Anamika Choudhary, Andy Cheuk‐Him Ng, Cezar Gavrilovici   +3 more
wiley   +1 more source

Dual regulation of Atf3 and Lonp1 as therapeutic targets in cerebral ischaemia-reperfusion injury. [PDF]

Stroke Vasc Neurol
Fan W, Zhou M, Zhou L, Tong J, Tan J, Shi W, Yu B.   +6 more
europepmc   +1 more source

Targeting the Nrf2/TGF‐β1/Smad Signaling Pathway: A Novel Strategy for Urolithin A to Alleviate Renal Fibrosis

Food Frontiers, EarlyView.
The diagram of the mechanism of action by which UroA regulates RF. ABSTRACT The global prevalence and mortality rates associated with chronic kidney disease (CKD) have been on a continuous rise over recent decades. Renal fibrosis (RF) serves as a critical factor in the progression of CKD to end‐stage renal disease.
Xue Wu, Jiating Li, Yonghui Dong, Jia Li, Ji Bian, Chao Liu, Hongbo Zhang, Lin Han, Min Wang   +8 more
wiley   +1 more source

Seipin-Mediated Lipid Droplet Formation in Cardiomyocytes Ameliorates Cardiac Ischemia/Reperfusion Injury. [PDF]

Adv Sci (Weinh)
Liu C, Zhang J, Chen Y, Shen G, Han Y, Zhou Z, Chen J, Kang X, Qu H, Duanmu J, Shang H, Li Y, Huang W, Zhang Y.   +13 more
europepmc   +1 more source

m6Am Methyltransferase Pcif1 Knockdown Attenuates Mouse Cerebral Ischemia-Reperfusion Injury in Vitro through Inhibiting Pdpk1 mRNA Translation

Bo Yang, Yanxia Sun, Wei Zhang, Chunchao Lv, Jiayu Xie   +4 more
openalex   +1 more source

Cardamonin Commands the Colonic Metabolite Columbianetin Acetate to Compete Against LPS in Binding HMGB1 in the Kidney, Preventing Lipopolysaccharide‐Induced Renal Tubular Pyroptosis

Food Frontiers, EarlyView.
Cardamonin upregulate sd the intestinal metabolite columbianetin acetate, which competitively bound HMGB1 to prevent LPS‐induced renal tubular cell pyroptosis (the figure is created with BioRender). ABSTRACT Sepsis‐associated acute kidney injury (SA‐AKI) results in high mortality due to the lack of effective interventions. The current study reports the
Zihui Zhou, Xuechun Sun, Jian Zhou, Huali Meng, Pengfei Fan, Yufeng Chu, Hao Wu   +6 more
wiley   +1 more source

Nuclear cell-free DNA on the loose: an early warning signal of ischemia-reperfusion injury in kidney transplantation. [PDF]

Front Immunol
Strandberg G, Trattner R, Martin M, Öberg CM, Raihle C, Slivca O, Alam S, Segelmark M, Christensson A, Nilsson B, Paul C, Blom AM, Biglarnia AR.   +12 more
europepmc   +1 more source

Maintenance of Carnitine Homeostasis as a Therapeutic Strategy to Attenuate Cisplatin‐Induced Acute Kidney Injury

Food Frontiers, EarlyView.
ABSTRACT Acute kidney injury (AKI) has emerged as a significant global public health concern due to its high morbidity and mortality rates. Cisplatin, a highly effective and widely used chemotherapeutic agent, is often limited in clinical application by its nephrotoxicity, particularly AKI.
Mingkang Zhang, Yazhi Wang, Xiujuan Wang, Yan Zhou, Yanrong Ma, Xin'an Wu   +5 more
wiley   +1 more source

Spinal cord-protective effect of resorcimoline for ischemia-reperfusion injury in a rabbit model. [PDF]

JTCVS Open
Kawahara Y, Kawashima T, Yoshimura K, Mori K, Nagashima R, Umeno T, Nishida H, Sato H, Higuchi A, Tokumaru O, Miyamoto S.   +10 more
europepmc   +1 more source