Results 211 to 220 of about 889,250 (400)

GlycoChat Uncovers Glycan–Lectin Circuits in the Tumor Microenvironment of Pancreatic Cancer

Advanced Science, EarlyView.
Aberrant glycosylation drives cancer progression, yet its role in the tumor microenvironment remains unclear. We developed GlycoChat to map glycan–lectin circuits at single‐cell resolution. We discovered that cancer cells induce immunosuppressive macrophage differentiation and impair phagocytosis through interactions with CLEC10A and SIGLEC3 ...
Dinh Xuan Tuan Anh, Sunanda Keisham, Arun Burramsetty, Lalhaba Oinam, Koichiro Kumano, Akihiro Kuno, Osamu Shimomura, Tatsuya Oda, Hiroaki Tateno   +8 more
wiley   +1 more source

Vocal Complexity Constrains the Dear Enemy Effect: A Comparative Study of Coal Tits and Green-Backed Tits. [PDF]

Ecol Evol
Zhao L, Zhang F, Liu J, Liang W.
europepmc   +1 more source

Flies expand the repertoire of protein structures that bind ice [PDF]

, 2015
Koli Basu, Laurie A. Graham, Robert L. Campbell, Peter L. Davies   +3 more
openalex   +1 more source

Aberrant Splicing Signatures Underpin Oligodendrocyte Damage in ALS and Neuron Loss in FTD

Advanced Science, EarlyView.
Integrating bulk and single‐nucleus RNA‐seq from ALS and FTD patients, we revealed distinct cellular dysfunctions, with severe oligodendrocyte damage in ALS and pronounced neuron loss in FTD. We identified cell‐type‐specific aberrant splicing events as potential biomarkers with robust classification performance, some of which produce de novo peptides ...
Chen Du, Yinming Li, Rong Wu, Yufei Shen, Jiayi Yang, Xuan Xiao, Yu Zhou   +6 more
wiley   +1 more source

Circulating T-cell receptor repertoire and clinicopathological correlations in breast cancer patients: immune repertoire analysis from the VGH-TAYLOR study. [PDF]

Breast Cancer Res
Tseng LM, Huang CC, Chen JL, Tsai YF, Chao TC, Wu WC, Lien PJ, Lin YS, Feng CJ, Chen YJ, Lai JI, Chiu JH, Hsu CY, Liu CY.   +13 more
europepmc   +1 more source

Modulation of Host Immunity by Helminths: The Expanding Repertoire of Parasite Effector Molecules

Immunity, 2018
Rick M. Maizels, H. Smits, H. McSorley
semanticscholar   +1 more source

Discovery of SKP2‐Recruiting PROTACs for Target Protein Degradation

Advanced Science, EarlyView.
Based on the SKP2‐targeting ligand SL1, we designed non‐covalent PROTACs by linking it with the BRD4 inhibitor JQ1 and the AR antagonist AL through a linker. These PROTACs successfully induced the ubiquitination of BRD4 and AR, followed by proteasome‐mediated degradation.
Guanjun Dong, Aima Huang, Ziqing Zhao, Bikai Lai, Xin Pan, Huiyu Yang, Xiaohan Xu, Tianwei Wang, Fangchen Zhao, Zhimin Zhang, Yongbo Xue, Guanjun Deng, Wenbin Deng, Jianwei Chen   +13 more
wiley   +1 more source

T cell receptor clonotypes predict human leukocyte antigen allele carriage and antigen exposure history. [PDF]

Commun Biol
ElAbd H, Mahdy AKH, Wacker EM, Gretsova M, Ellinghaus D, Dempfile A, Franke A.   +6 more
europepmc   +1 more source

Coping Repertoire in Caregivers of Schizophrenic Patients: An Indian Study

, 2014
Iosr Journals, Ridhi Gupta
openalex   +1 more source

Data from Expanding the Repertoire for “Large Small Molecules”: Prodrug ABBV-167 Efficiently Converts to Venetoclax with Reduced Food Effect in Healthy Volunteers

, 2023
Ahmed Hamed Salem, Zhi‐Fu Tao, Orlando Francisco Amodeo Bueno, Jie Chen, Shuang Chen, Rohinton Edalji, Steven W. Elmore, Keith M. Fournier, Kaid C. Harper, Richard Hong, Gary J. Jenkins, Jianguo Ji, Russell A. Judge, J. Cory Kalvass, Russell C. Klix, Yi‐Yin Ku, Joel Johansson, Richard A. Marks, Kennan C. Marsh, Rajeev Menon, Chang H. Park, Darren C. Phillips, Yu‐Ming Pu, Saul H. Rosenberg, Yeshwant D. Sanzgiri, Ahmad Y. Sheikh, Yi Shi, DeAnne Stolarik, Ahmed A. Suleiman, Xilu Wang, Geoff G. Z. Zhang, Nathaniel D. Catron, Andrew J. Souers   +32 more
openalex   +1 more source