Results 11 to 20 of about 71,813 (221)
FASEB bioAdvances, 2020 Human spaceflight endeavors present an opportunity to expand our presence beyond Earth. To this end, it is crucial to understand and diagnose effects of long‐term space travel on the human body.
Julian Rubinfien +13 more
semanticscholar +1 more source
Consistent ultra-long DNA sequencing with automated slow pipetting
BMC Genomics, 2021 Background Oxford Nanopore Technologies’ instruments can sequence reads of great length. Long reads improve sequence assemblies by unambiguously spanning repetitive elements of the genome.
Trent M. Prall +7 more
doaj +1 more source
Nature Communications, 2023 Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are neurodegenerative diseases that exist on a clinico-pathogenetic spectrum, designated ALS/FTD.
Federica Raguseo +15 more
doaj +1 more source
The Nucleus, 2017 Cells have evolved intricate mechanisms to maintain genome stability despite allowing mutational changes to drive evolutionary adaptation. Repetitive DNA sequences, which represent the bulk of most genomes, are a major threat to genome stability often ...
Amanda C. Hall +3 more
semanticscholar +1 more source
Food Frontiers, 2023 Salmonella is one of the most common zoonotic foodborne pathogens and can cause serious threats to public health and global economy. A dual‐mode biosensing platform was demonstrated based on cascaded signal amplification coupled with DNA‐functionalized ...
Jing‐bo Jiao +9 more
doaj +1 more source
Surgical and Experimental Pathology, 2019 Gastrointestinal Stromal Tumors (GIST) present different types of mutations that may or may not be sensitive to specific target therapy. The laboratory procedure required to prepare histological sections traditionally demands multiple steps, making the ...
Denise Barcelos +4 more
doaj +1 more source
BioTechniques, 2008 A rapid capture technique was developed to efficiently isolate specific DNA targets from a variety of genomes. The specificity can be easily adapted to any target for which partial sequence is known, allowing for the isolation of a wide set of target ...
Judy St. John, Thomas W. Quinn
doaj +1 more source
The challenge of small-scale repeats for indel discovery
Frontiers in Bioengineering and Biotechnology, 2015 Repetitive sequences are abundant in the human genome. Different classes of repetitive DNA sequences, including simple repeats, tandem repeats, segmental duplications, interspersed repeats and other elements, collectively span more than 50% of the genome.
Giuseppe eNarzisi, Michael C Schatz
doaj +1 more source
Systematic identification of stem-loop containing sequence families in bacterial genomes
BMC Genomics, 2008 Background Analysis of non-coding sequences in several bacterial genomes brought to the identification of families of repeated sequences, able to fold as secondary structures.
Silvestro Giustina +4 more
doaj +1 more source
Frontiers in Pharmacology, 2020 The clinical benefit of therapies using Mesenchymal Stem Cells (MSCs) is attributable to their pleiotropic effect over cells and tissues, mainly through their secretome.
Gabriela Zavala +16 more
doaj +1 more source