Solving the riddle of codon usage preferences: a test for translational selection [PDF]
, 2004 Translational selection is responsible for the unequal usage of synonymous codons in protein coding genes in a wide variety of organisms. It is one of the most subtle and pervasive forces of molecular evolution, yet, establishing the underlying causes ...
dos Reis, M. +2 more
core +6 more sources
Delineation of individual human chromosomes in metaphase and interphase cells by in situ suppression hybridization using recombinant DNA libraries [PDF]
, 1988 A method of in situ hybridization for visualizing individual human chromosomes from pter to qter, both in metaphase spreads and interphase nuclei, is reported.
B Trask +39 more
core +1 more source
The structure and expression of mammalian gene clusters [PDF]
, 1982 Chromosomes often serve as one of the most important molecular aspects of studying the evolution of species. Indeed, most of the crucial mutations that led to differentiation of species during the evolution have occurred at the chromosomal level ...
Boer, E. de +11 more
core +5 more sources
RNA-dependent stabilization of SUV39H1 at constitutive heterochromatin
eLife, 2017 Heterochromatin formed by the SUV39 histone methyltransferases represses transcription from repetitive DNA sequences and ensures genomic stability. How SUV39 enzymes localize to their target genomic loci remains unclear.
Whitney L Johnson +7 more
doaj +1 more source
The Echinococcus canadensis (G7) genome: A key knowledge of parasitic platyhelminth human diseases [PDF]
, 2017 Background: The parasite Echinococcus canadensis (G7) (phylum Platyhelminthes, class Cestoda) is one of the causative agents of echinococcosis. Echinococcosis is a worldwide chronic zoonosis affecting humans as well as domestic and wild mammals, which ...
A Bankevich +109 more
core +8 more sources
Surgical and Experimental Pathology, 2019 Gastrointestinal Stromal Tumors (GIST) present different types of mutations that may or may not be sensitive to specific target therapy. The laboratory procedure required to prepare histological sections traditionally demands multiple steps, making the ...
Denise Barcelos +4 more
doaj +1 more source
Food Frontiers, 2023 Salmonella is one of the most common zoonotic foodborne pathogens and can cause serious threats to public health and global economy. A dual‐mode biosensing platform was demonstrated based on cascaded signal amplification coupled with DNA‐functionalized ...
Jing‐bo Jiao +9 more
doaj +1 more source
Assessing the Epigenetic Status of Human Telomeres [PDF]
, 2019 The epigenetic modifications of human telomeres play a relevant role in telomere functions and cell proliferation. Therefore, their study is becoming an issue of major interest.
Vaquero Sedas, María Isabel +1 more
core +1 more source
Blueprint for a high-performance biomaterial: full-length spider dragline silk genes. [PDF]
, 2007 Spider dragline (major ampullate) silk outperforms virtually all other natural and manmade materials in terms of tensile strength and toughness. For this reason, the mass-production of artificial spider silks through transgenic technologies has been a ...
Ayoub, Nadia A +4 more
core +8 more sources
Complete Sequences of Organelle Genomes from the Medicinal Plant Rhazya Stricta (Apocynaceae) and Contrasting Patterns of Mitochondrial Genome Evolution Across Asterids [PDF]
, 2014 Rhazya stricta is native to arid regions in South Asia and the Middle East and is used extensively in folk medicine to treat a wide range of diseases.
Baeshen, Mohammed N. +7 more
core +1 more source