Results 21 to 30 of about 79,729 (116)

The evolutionary dynamics of variant antigen genes in Babesia reveal a history of genomic innovation underlying host-parasite interaction [PDF]

, 2014
Babesia spp. are tick-borne, intraerythrocytic hemoparasites that use antigenic variation to resist host immunity, through sequential modification of the parasite-derived variant erythrocyte surface antigen (VESA) expressed on the infected red blood cell
Allred, David R., Berriman, Matt, Darby, Alistair, Echaide, Ignacio Eduardo, Farber, Marisa, Gahlot, Sunayna, Gamble, John, Gupta, Diness, Gupta, Yask, Hall, Neil, Jackson, Andrew P., Jackson, Louise, Lingelbach, Klaus, Malandrin, Laurence, Malas, Tareq B., Moussa, Ehab, Nair, Mridul, Otto, Thomas D., Pain, Arnab, Quail, Mike A., Ramaprasad, Abhinay, Reid, Adam J., Sanders, Mandy, Sharma, Jyotsna, Shiels, Brian, Tait, Andy, Tracey, Alan, Wastling, Jonathan M., Weir, William, Willadsen, Peter, Xia, Dong   +30 more
core   +5 more sources

Rapid capture of DNA targets

BioTechniques, 2008
A rapid capture technique was developed to efficiently isolate specific DNA targets from a variety of genomes. The specificity can be easily adapted to any target for which partial sequence is known, allowing for the isolation of a wide set of target ...
Judy St. John, Thomas W. Quinn
doaj   +1 more source

Small Open Reading Frames, Non-Coding RNAs and Repetitive Elements in Bradyrhizobium japonicum USDA 110 [PDF]

, 2016
Small open reading frames (sORFs) and genes for non-coding RNAs are poorly investigated components of most genomes. Our analysis of 1391 ORFs recently annotated in the soybean symbiont Bradyrhizobium japonicum USDA 110 revealed that 78% of them contain ...
Cuklina, Jelena, Evguenieva-Hackenberg, Elena, Gelfand, Mikhail S., Hahn, Julia, Thalmann, Sebastian, Tsoy, Olga V.   +5 more
core   +2 more sources

The challenge of small-scale repeats for indel discovery

Frontiers in Bioengineering and Biotechnology, 2015
Repetitive sequences are abundant in the human genome. Different classes of repetitive DNA sequences, including simple repeats, tandem repeats, segmental duplications, interspersed repeats and other elements, collectively span more than 50% of the genome.
Giuseppe eNarzisi, Michael C Schatz
doaj   +1 more source

Systematic identification of stem-loop containing sequence families in bacterial genomes

BMC Genomics, 2008
Background Analysis of non-coding sequences in several bacterial genomes brought to the identification of families of repeated sequences, able to fold as secondary structures.
Silvestro Giustina, Petrillo Mauro, Cozzuto Luca, Di Nocera Pier, Paolella Giovanni   +4 more
doaj   +1 more source

Molecular cytogenetic characterisation of Salix viminalis L. using repetitive DNA sequences [PDF]

, 2013
Salix viminalis L. (2n=38) is a diploid dicot species belonging to the Salix genus of the Salicaceae family. This short-rotation woody crop is one of the most important renewable bioenergy resources worldwide.
Dudits, Dénes, Linc, Gabriella, Láng Molnár, Márta, Németh, Anna Viktória   +3 more
core   +1 more source

Semipermeable Cellulose Beads Allow Selective and Continuous Release of Small Extracellular Vesicles (sEV) From Encapsulated Cells

Frontiers in Pharmacology, 2020
The clinical benefit of therapies using Mesenchymal Stem Cells (MSCs) is attributable to their pleiotropic effect over cells and tissues, mainly through their secretome.
Gabriela Zavala, Gabriela Zavala, María-Paz Ramos, María-Paz Ramos, Aliosha I. Figueroa-Valdés, Aliosha I. Figueroa-Valdés, Pablo Cisternas, Ursula Wyneken, Macarena Hernández, Macarena Hernández, Pauline Toa, Brian Salmons, John Dangerfield, Walter H. Gunzburg, Maroun Khoury, Maroun Khoury, Maroun Khoury   +16 more
doaj   +1 more source

Accelerated Evolution of the ASPM Gene Controlling Brain Size Begins Prior to Human Brain Expansion [PDF]

, 2004
Primary microcephaly (MCPH) is a neurodevelopmental disorder characterized by global reduction in cerebral cortical volume. The microcephalic brain has a volume comparable to that of early hominids, raising the possibility that some MCPH genes may have ...
Abeysinghe, Aota, Benson, Bernardi, Bond, Bond, Chen, Chenn, Chuzhanova, Clark, Crandall, Dewyse, do Carmo Avides, Duret, Endo, Evans, Galtier, Gould, Hughes, Jurka, Kent, Kouprina, Kreitman, McCreary, McDonald, Mochida, Morgenstern, Noskov, Polushin, Rehen, Riparbelli, Ripoll, Roberts, Rudiger, Sharp, Sharp, Tobias, Wood, Yang, Yang, Zhang   +40 more
core   +3 more sources

Genomic Selective Constraints in Murid Noncoding DNA [PDF]

, 2006
Recent work has suggested that there are many more selectively constrained, functional noncoding than coding sites in mammalian genomes. However, little is known about how selective constraint varies amongst different classes of noncoding DNA.
Altschul, Bejerano, Bejerano, Boissinot, Bray, Britten, Casane, Chamary, Chamary, Cooper, Cooper, Daniel J. Gaffney, Deininger, Dermitzakis, Dermitzakis, Dermitzakis, Eisenberg, Eyre-Walker, Fairbrother, Frazer, Gaffney, Gibbs, Hanawalt, Hubbard, Jaeger, Kamal, Keightley, Keightley, Keightley, Keightley, Kimura, Kondrashov, Kondrashov, Lander, Li, Margulies, Meunier, Mi, Mikkelsen, Nagylaki, Nelson, Parmley, Peter D. Keightley, Seoighe, Siepel, Sironi, Sorek, Tamura, Thomas, Thompson, Urrutia, Vinogradov, Vinogradov, Waterston, Webster, Yelin   +55 more
core   +3 more sources

Of bits and bugs [PDF]

, 2010
Pur-α is a nucleic acid-binding protein involved in cell cycle control, transcription, and neuronal function. Initially no prediction of the three-dimensional structure of Pur-α was possible.
Graebsch, Almut, Kostrewa, Dirk, Niessing, Dierk, Roche, Stéphane, Söding, Johannes   +4 more
core   +1 more source