Results 61 to 70 of about 108,626 (229)

Cost-effectiveness of the Adaptive Implementation of Effective Programs Trial (ADEPT): approaches to adopting implementation strategies

Implementation Science, 2020
Background Theory-based methods to support the uptake of evidence-based practices (EBPs) are critical to improving mental health outcomes. Implementation strategy costs can be substantial, and few have been rigorously evaluated. The purpose of this study
Andria B. Eisman, David W. Hutton, Lisa A. Prosser, Shawna N. Smith, Amy M. Kilbourne   +4 more
doaj   +1 more source

Evaluation and guide for embedding opioid use disorder education in health professions’ curricula

BMC Medical Education, 2023
Background Morbidity and mortality from Opioid Use Disorder is a health crisis in the United States. During the COVID-19 pandemic, there was a devastating increase of 38.4% in overdose deaths from the 12-month period leading up to June 2019 compared with
Julie G. Salvador, Sindy L. Bolaños-Sacoman, Joanna G. Katzman, Ann E. Morrison, Lindsay E. Fox, Jennifer S. Schneider, Snehal R. Bhatt, Tyler W. Kincaid, V. Ann Waldorf   +8 more
doaj   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Laying a Solid Foundation: Strategies for Effective Program Replication [PDF]

, 2009
With limited funds available for social investment, policymakers and philanthropists are naturally interested in supporting programs with the greatest chance of effectiveness and the ability to benefit the largest number of people.
Becca Raley, Geri Summerville
core  

A randomized trial of adapted versus standard versions of the Transdiagnostic Intervention for Sleep and Circadian Dysfunction implemented via facilitation and delivered by community mental health providers: improving the “fit” of psychological treatments by adapting to context

Implementation Science
Background Grounded in the Integrated Promoting Action on Research Implementation in Health Services framework (i-PARIHS) and the Replicating Effective Programs framework (REP), the goal is to determine if the use of theory, data and end-user ...
Allison G. Harvey, Emma R. Agnew, Rafael Esteva Hache, Julia M. Spencer, Marlen Diaz, Estephania Ovalle Patino, Anne Milner, Lu Dong, Amy M. Kilbourne, Daniel J. Buysse, Catherine A. Callaway, Laurel D. Sarfan   +11 more
doaj   +1 more source

Preparing to launch the ‘Thinking Healthy Programme’ perinatal depression intervention in Urban Lima, Peru: experiences from the field

Cambridge Prisms: Global Mental Health, 2018
Background.An estimated 19–25% of perinatal women in low- and middle-income countries are affected by depression which, untreated, is associated with multiple health problems for mothers and children.
B. S. Eappen, M. Aguilar, K. Ramos, C. Contreras, M. C. Prom, P. Scorza, B. Gelaye, M. Rondon, G. Raviola, J. T. Galea   +9 more
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

From Novelty to Expectation: Recommendations to Develop a System of Campus Support for Foster Youth [PDF]

, 2007
As longtime funders of efforts to promote educational opportunity for current and former foster youth, the Walter S. Johnson Foundation (WSJF) and Stuart Foundation have been in the forefront of efforts to replicate successful models of campus support ...
David Pontecorvo, Kris Putnam-Walkerly
core  

Technology Evaluation and Assessment Criteria for Health Apps (TEACH-Apps): Pilot Study

Journal of Medical Internet Research, 2020
BackgroundDespite the emergence of app evaluation tools, there remains no well-defined process receptive to diverse local needs, rigorous standards, and current content. The need for such a process to assist in the implementation of app evaluation across
Camacho, Erica, Hoffman, Liza, Lagan, Sarah, Rodriguez-Villa, Elena, Rauseo-Ricupero, Natali, Wisniewski, Hannah, Henson, Philip, Torous, John   +7 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source