Results 231 to 240 of about 1,569,783 (304)

ATM promotes nucleolytic processing of reversed replication forks during DNA interstrand cross-link repair. [PDF]

Nat Commun
Altshuller M, Shi G, MacKrell VA, Tzeng J, Nigam R, Konsler JK, Wang TY, Wang Y, Grogan EJ, Ozua OE, Campbell JL, Dewar JM, Chou TF, Shen B, Semlow DR.   +14 more
europepmc   +1 more source

Surface modification of 3D‐printed polycaprolactone scaffolds with silk fibroin for bone tissue engineering

FEBS Open Bio, EarlyView.
Coating 3D‐printed PCL scaffolds with silk fibroin can improve biocompatibility and bone cell adhesion. One innovative design for tissue‐engineering scaffolds uses 3D printing technology. Here, we used polycaprolactone (PCL) filament as a biocompatible material to design a porous 3D scaffold for bone tissue engineering.
Hamed Koeini, Esmaeil Biazar, Davood Zaeifi, Reza Zeinali, Saeed Heidari‐Keshel, Amimasoud Hassanour, Helia Saheli, Arezou Mehrabi   +7 more
wiley   +1 more source

Human cytomegalovirus exploits host chromatin remodeler MORC2 to promote the DNA damage response on viral genomes. [PDF]

PLoS Pathog
Jeong J, Jeong D, Lee S, Park J, Kim H, Ahn K.   +5 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Glucocorticoids Do Not Enhance BK Polyomavirus Replication in Human Renal Proximal Tubular Epithelial Cells In Vitro. [PDF]

Clin Transl Sci
Moest WT, Lalai RA, Prins J, de Vries APJ, Wessels E, van Kooten C, Feltkamp MCW, Rotmans JI.   +7 more
europepmc   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

The 7SK small nuclear ribonucleoprotein links the cell responses to transcription and replication stress by promoting replication fork reversal and homologous recombination. [PDF]

Nucleic Acids Res
Bowry A, Wilson C, Kelly RDW, Wilkins RJ, Walker AK, Varghese CS, Alshatti ZAM, Murphy-Hollies S, Morris JR, Egloff S, Kanhere A, Petermann E.   +11 more
europepmc   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Mathematical modeling of <i>in vitro</i> replication dynamics for multiple highly pathogenic avian influenza clade 2.3.4.4 viruses in chicken and duck cells. [PDF]

Microbiol Spectr
Bordes L, Hobbelen P, Blokker E, van der Poel WHM, Beauchemin CAA, Beerens N, Gonzales JL.   +6 more
europepmc   +1 more source