Results 61 to 70 of about 2,070,021 (273)
Avoiding the elephant in the room: The real reasons behind our research crisis
SA Journal of Industrial Psychology, 2019 Problemification: In recent years, the so-called publication crisis has reached alarming proportions, and the psychology and industrial psychology profession are not left unscathed.
Crystal Hoole
doaj +1 more source
Attachment & Human Development, 2021 In the biomedical, behavioral and neurobiological sciences reproducibility and replicability of research results have become a major issue. The question is whether attachment research is also plagued by lack of replicability, and if so whether one can ...
Marinus H. van IJzendoorn +1 more
semanticscholar +1 more source
Psychology’s Replication Crisis and Clinical Psychological Science
Annual Review of Clinical Psychology, 2018 Despite increasing interest in issues of replicability, open science, research transparency, and improving methods and practices in psychological science, the clinical psychology community has been slow to engage. This has been slowly shifting, and the authors of the present article hope to facilitate this emerging dialogue.
Jennifer L Tackett +3 more
openaire +3 more sources
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Beyond ‘significance’: principles and practice of the Analysis of Credibility [PDF]
Royal Society Open Science, 2018 The inferential inadequacies of statistical significance testing are now widely recognized. There is, however, no consensus on how to move research into a ‘post p
Robert A. J. Matthews
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The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
European Journal of Psychotraumatology, 2019 Adopting Registered Reports is an important step for the European Journal of Psychotraumatology to promote open science practices in the field of psychotrauma research. However, adopting these practices requires us as individual researchers to change our
Ineke Wessel, Helen Niemeyer
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The Cooperative Revolution Reaches Clinical Psychology and Psychotherapy: An Example From Germany
Clinical Psychology in Europe, 2021 [Background] Psychology is at the beginning of a cooperative revolution. Traditionally, psychological research has been conducted by individual labs, limiting its scope in clinical samples and promoting replication problems.
Jürgen Margraf +9 more
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source