Results 81 to 90 of about 1,779,695 (298)
The Replication Database: Documenting the Replicability of Psychological Science
Journal of Open Psychology DataIn psychological science, replicability—repeating a study with a new sample achieving consistent results (Parsons et al., 2022)—is critical for affirming the validity of scientific findings.
Lukas Röseler +96 more
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Replication crisis: pre-post educational video assessing psychology students’ behaviors and attitudes [PDF]
In the past decade, replication, crises surrounding replication, fraud, and data collection have dominated discussions in psychology. Open Science, a cooperative approach using digital technologies, addresses these issues.
Foster, Gillian
core
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Victim impact statements / reports: a guide for victim supporters from Rape Crisis Network Ireland [PDF]
, 2011 Funded by the Commission for the Support of Victims of ...
Rape Crisis Network Ireland
core
Reversal of terminal differentiation and control of DNA replication [PDF]
, 1993 DNA replication in mammalian cells occurs in discrete nuclear foci. Here we show that terminally differentiated myotubes can be induced to reenter S phase and show the same pattern of replication foci as cycling cells.
Cardoso, M. Cristina +4 more
core +2 more sources
A tutorial on hunting statistical significance by chasing N
Frontiers in Psychology, 2016 There is increasing concern about the replicability of studies in psychology and cognitive neuroscience. Hidden data dredging (also called p-hacking) is a major contributor to this crisis because it substantially increases Type I error resulting in a ...
Denes Szucs
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
, 2022 Replication package including code and data required to replicate all results in the main paper and the online appendix of McCarthy, David, James Sefton, Ronald Lee and Joze Sambt: "Generational Wealth Accounts: did public and private inter-generational ...
David McCarthy +3 more
core +1 more source
Frontiers in Psychology, 2019 Despite its long tradition in social psychology, we consider that Cognitive Dissonance Theory presents serious flaws concerning its methodology which question the relevance of the theory, limit breakthroughs, and hinder the evaluation of its core ...
David C. Vaidis, Alexandre Bran
doaj +1 more source