Results 21 to 30 of about 260,016 (217)
MicroRNA-520a suppresses HBV replication in HepG2.2.15 cells by inactivating AKT
Journal of International Medical Research, 2018 Objective To investigate whether the mechanism by which a microRNA, miR-520a, suppresses the replication of hepatitis B virus (HBV) involves the regulation of the serine/threonine kinase ( AKT ) gene. Methods The effects of miR-520a on the proliferation,
Wei Sun, Jinqian Zhang, Jinglong Chen
doaj +1 more source
Entropy, 2021 A function which transforms a continuous random variable such that it has a specified distribution is called a replicating function. We suppose that functions may be assigned a price, and study an optimization problem in which the cheapest approximation ...
Brendan K. Beare
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Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola +4 more
wiley +1 more source
Using Cubic Splines in Crop Insurance Models – A Replication Study
German Journal of Agricultural EconomicsThis study replicates the work of Bucheli et al. (2022) to evaluate the reliability and generalizability of their findings on the use of cubic spline methods in weather index insurance design in Eastern Germany. The study consists of two parts: a direct
Lorenz Schmidt +3 more
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Journal of Diabetes Research, 2020 Background. The relationship between the IgG glycan panel and type 2 diabetes remains unclear in Chinese population. We aimed to investigate the association of the IgG glycan profile and glycan score with type 2 diabetes. Methods.
Zhiyuan Wu +11 more
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FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Asymmetry indices for analysis and prediction of replication origins in eukaryotic genomes. [PDF]
PLoS ONE, 2012 DNA replication was recently shown to induce the formation of compositional skews in the genomes of the yeasts Saccharomyces cerevisiae and Kluyveromyces lactis.
Marie-Claude Marsolier-Kergoat
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Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The Measurement of Tracking Errors of Gold ETFS: Evidence from China
Applied Finance Letters, 2016 This paper presents the first study on the measurement of tracking errors using daily figures for gold exchange-traded funds (ETFs) in China. Three methods are employed to measure tracking errors: 1) calculating the absolute error measure, 2) calculating
Wei-Fong Pan, Ting Li
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