Replicative senescence induction in single cells is not predicted by telomere length, dysfunction, or oxidation. [PDF]
iSciencePassanisi V, Spencer SL.
europepmc +1 more source
Ezh2 Inhibits Replicative Senescence of Atrial Fibroblasts Through Promotion of H3K27me3 in the Promoter Regions of CDKN2a and Timp4 Genes. [PDF]
J Inflamm Res, 2022 Li Y +7 more
europepmc +1 more source
Neurovascular Contacts in the Pathophysiology of Neuralgic Amyotrophy: An Observational Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Neuralgic amyotrophy (NA) is a prevalent, monophasic, multifocal immune‐mediated neuropathy. A distinctive characteristic of the disease is the occurrence of nerve or fascicle constrictions and torsions (NA‐associated focal nerve lesions, NAFL). The pathophysiology underlying this phenomenon remains to be fully elucidated.
Johannes Fabian Holle +4 more
wiley +1 more source
Isatis tinctoria L. Leaf Extract Inhibits Replicative Senescence in Dermal Fibroblasts by Regulating mTOR-NF-κB-SASP Signaling. [PDF]
Nutrients, 2022 Woo J +8 more
europepmc +1 more source
Metabolic and Microvascular Risk Factors Associated With Brain Health in Type 1 Diabetes
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT We examined relationships between metabolic factors, microvascular complications, and brain health in adults with type 1 diabetes. Fifty‐one adults were assessed for metabolic risk factors, microvascular complications, and cognitive function, with a subset completing brain MRI.
Jihyun Park +7 more
wiley +1 more source
Differential miRNA expression during replicative senescence of dental pulp stem cells with potential for forensic age assessment. [PDF]
Sci RepRojas-Torres J +7 more
europepmc +1 more source
A Novel Biochemical Study of Anti-Dermal Fibroblast Replicative Senescence Potential of Panax Notoginseng Oligosaccharides. [PDF]
Front Pharmacol, 2021 Zhai L +7 more
europepmc +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
γ-Oryzanol Ameliorates Endothelial Replicative Senescence via Downregulation of SGLT2 Expression to Attenuate NADPH-Driven Oxidative Stress. [PDF]
Biomol Ther (Seoul)Shiwakoti S +6 more
europepmc +1 more source
Telomere shortening causes distinct cell division regimes during replicative senescence in Saccharomyces cerevisiae. [PDF]
Cell Biosci, 2021 Martin H, Doumic M, Teixeira MT, Xu Z.
europepmc +1 more source