Results 71 to 80 of about 30,157 (159)
MicrobiologyOpen, Volume 15, Issue 2, April 2026.Tn‐seq analysis of Thermus thermophilus genome reveals insertions in almost all genes, this is, there is no clear discrimination of essential genes. A similar result has not been reported in other Tn‐seq analysis of bacterial genomes so far. The polyploidy of the Thermus genome could explain the apparent non‐essentiality of key genes.
Cristina L. Gómez‐Campo +6 more
wiley +1 more source
Encounter of T7 Replisome with Abasic DNA Lesion
, 2019 In order to monitor the T7 replisome fate upon encountering abasic lesion, I optimized a single molecule flow stretching assay where the replisome encounters either abasic site or undamaged site inserted at 3.5 kilobases from the replication fork.
Alhudhali, Lubna F.
core +1 more source
The Eukaryotic Mismatch Recognition Complexes Track with the Replisome during DNA Synthesis.
PLoS Genetics, 2015 During replication, mismatch repair proteins recognize and repair mispaired bases that escape the proofreading activity of DNA polymerase. In this work, we tested the model that the eukaryotic mismatch recognition complex tracks with the advancing ...
Joanna E Haye, Alison E Gammie
doaj +1 more source
Mcm10 promotes rapid isomerization of CMG-DNA for replisome bypass of lagging strand DNA blocks
eLife, 2017 Replicative helicases in all cell types are hexameric rings that unwind DNA by steric exclusion in which the helicase encircles the tracking strand only and excludes the other strand from the ring.
Lance D Langston +7 more
doaj +1 more source
Advanced Science, Volume 13, Issue 17, 23 March 2026.In the H‐type electrolytic cell, carbon dioxide is reduced to acetic acid via electro‐microbial catalysis. The simply processed acetic acid is further converted through biological fermentation into high‐value‐added products, including acrylic acid, L‐lactic acid, and β‐alanine.
Kaixing Xiao +8 more
wiley +1 more source
Coumarin‐Augmented Thiazole Hybrids as Dual Anticancer and Antibacterial Agents
Chemical Biology &Drug Design, Volume 107, Issue 2, February 2026.Compound 13, a coumarin‐thiazole hybrid, is shown engaging the ATP‐binding site of S. aureus GyrB through a novel hydrogen bond with residue SER129. The molecule exhibits dual antibacterial and anticancer activity, supporting its potential as a dual‐target topoisomerase inhibitor.
Islam K. Matar +6 more
wiley +1 more source
Where and When Bacterial Chromosome Replication Starts: A Single Cell Perspective
Frontiers in Microbiology, 2018 Bacterial chromosomes have a single, unique replication origin (named oriC), from which DNA synthesis starts. This study describes methods of visualizing oriC regions and the chromosome replication in single living bacterial cells in real-time.
Damian Trojanowski +2 more
doaj +1 more source
Journal of Fish Biology, Volume 108, Issue 2, Page 676-693, February 2026.Abstract In the context of current global change, variations in water temperature are one of the environmental conditions with serious consequences for marine life, including reproductive processes. In the small spotted catshark Scyliorhinus canicula, spermatogenesis occurs in spermatocysts composed of synchronously developing germ cells associated ...
Fabian Jeanne +4 more
wiley +1 more source
, 2021 Supplemental tables for Journal of Cell Biology paper (10.1083/jcb.202009147): Fan, Y., Köberlin, M.S., Ratnayeke, N., Liu, C., Deshpande, M., Gerhardt, J., and Meyer, T. (2021).
Fan, Yilin
core +1 more source
Remodeling of Interstrand Crosslink Proximal Replisomes Is Dependent on ATR, FANCM, and FANCD2
Cell Reports, 2019 Summary: Eukaryotic replisomes are driven by the mini chromosome maintenance (MCM [M]) helicase complex, an offset ring locked around the template for leading strand synthesis by CDC45 (C) and GINS (G) proteins.
Jing Huang +14 more
doaj +1 more source