Results 1 to 10 of about 100,632 (325)
Targeted Repolarization of Tumor‐Associated Macrophages via Imidazoquinoline‐Linked Nanobodies
Advanced Science, 2021 Tumor‐associated macrophages (TAMs) promote the immune suppressive microenvironment inside tumors and are, therefore, considered as a promising target for the next generation of cancer immunotherapies.
Evangelia Bolli +13 more
doaj +2 more sources
Electrocardiographic Imaging of Repolarization Abnormalities
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021 Background Dispersion and gradients in repolarization have been associated with life‐threatening arrhythmias, but are difficult to quantify precisely from surface electrocardiography.
Laura R. Bear +13 more
doaj +2 more sources
Effects of early afterdepolarizations on excitation patterns in an accurate model of the human ventricles [PDF]
PLoS ONE, 2017 Early Afterdepolarizations, EADs, are defined as the reversal of the action potential before completion of the repolarization phase, which can result in ectopic beats.
Panfilov, Alexander +3 more
core +11 more sources
Frontiers in Physiology, 2017 Background: Cellular repolarization abnormalities occur unpredictably due to disease and drug effects, and can occur even in cardiomyocytes that exhibit normal action potentials (AP) under control conditions.
Oliver J. Britton +4 more
doaj +2 more sources
Early Repolarization Syndrome: Diagnostic and Therapeutic Approach
Frontiers in Cardiovascular Medicine, 2018 An early repolarization pattern can be observed in 1% up to 13% of the overall population. Whereas, this pattern was associated with a benign outcome for many years, several more recent studies demonstrated an association between early repolarization and
Felix Bourier +31 more
doaj +2 more sources
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016 BackgroundDiabetes is associated with prolongation of the QT interval of the electrocardiogram and enhanced dispersion of ventricular repolarization, factors that, together with atherosclerosis and myocardial ischemia, may promote the occurrence of ...
Marianna Meo +12 more
doaj +2 more sources
Macrophage Repolarization as a Therapeutic Strategy for Osteosarcoma
International Journal of Molecular Sciences, 2023 Macrophages are versatile immune cells and can adapt to both external stimuli and their surrounding environment. Macrophages are categorized into two major categories; M1 macrophages release pro-inflammatory cytokines and produce protective responses ...
N. Anand, K. H. Peh, J. Kolesar
semanticscholar +1 more source
Chronic Heart Failure Management: Monitoring Patients and Intercepting Exacerbations
Reviews in Cardiovascular Medicine, 2023 Despite significant progress in the field of therapy and management, chronic heart failure (CHF) still remains one of the most common causes of morbidity and mortality, especially among the elderly in Western countries.
Gianfranco Piccirillo +3 more
doaj +1 more source
Nature Communications, 2022 Arrhythmias originating in scarred ventricular myocardium are a major cause of death, but the underlying mechanism allowing these rhythms to exist remains unknown.
Kamilla Kelemen +4 more
semanticscholar +1 more source
Science Translational Medicine, 2021 Description Premature beats originating in clinically concealed areas of local early repolarization promote ventricular arrhythmias and sudden cardiac arrest.
Matthijs J. M. Cluitmans +20 more
semanticscholar +1 more source