Results 21 to 30 of about 105,162 (327)

Sex‐specific activation of SK current by isoproterenol facilitates action potential triangulation and arrhythmogenesis in rabbit ventricles [PDF]

, 2018
Sex has a large influence on cardiac electrophysiological properties. Whether sex differences exist in apamin‐sensitive small conductance Ca2+‐activated K+ (SK) current (IKAS) remains unknown.
Chen, Mu, Chen, Peng-Sheng, Chen, Zhenhui, Everett, Thomas H., IV, Guo, Shuai, Lin, Shien-Fong, Rubart-von der Lohe, Michael, Wang, Zhuo, Weiss, James N., Xu, Dong-Zhu, Yin, Dechun   +10 more
core   +1 more source

Role of the Purkinje-Muscle Junction on the Ventricular Repolarization Heterogeneity in the Healthy and Ischemic Ovine Ventricular Myocardium

Frontiers in Physiology, 2018
Alteration of action potential duration (APD) heterogeneity contributes to arrhythmogenesis. Purkinje-muscle junctions (PMJs) present differential electrophysiological properties including longer APD.
Marine E. Martinez, Marine E. Martinez, Marine E. Martinez, Richard D. Walton, Richard D. Walton, Richard D. Walton, Jason D. Bayer, Jason D. Bayer, Michel Haïssaguerre, Michel Haïssaguerre, Michel Haïssaguerre, Michel Haïssaguerre, Edward J. Vigmond, Edward J. Vigmond, Mélèze Hocini, Mélèze Hocini, Mélèze Hocini, Mélèze Hocini, Olivier Bernus, Olivier Bernus, Olivier Bernus   +20 more
doaj   +1 more source

Abnormal Action Potentials Associated with the Shaker Complex Locus of Drosophila [PDF]

, 1981
Intracellular recordings of action potentials were made from the cervical giant axon in Shaker (Sh) mutants and normal Drosophila. The mutants showed abnormally long delays in repolarization.
Ferrus, Alberto, Fujita, Shinobu C., Tanouye, Mark A.   +2 more
core   +1 more source

Temporal Variability in Electrocardiographic Indices in Subjects With Brugada Patterns

Frontiers in Physiology, 2020
IntroductionPatients with Brugada electrocardiographic (ECG) patterns have differing levels of arrhythmic risk. We hypothesized that temporal variations in certain ECG markers may provide additional value for risk stratification.
Sharen Lee, Jiandong Zhou, Tong Liu, Konstantinos P. Letsas, Sandeep S. Hothi, Vassilios S. Vassiliou, Guoliang Li, Adrian Baranchuk, Raymond W. Sy, Raymond W. Sy, Dong Chang, Qingpeng Zhang, Gary Tse, Gary Tse   +13 more
doaj   +1 more source

Electrocardiographic markers of myocardial conduction and repolarization in Boxer dogs [PDF]

Pesquisa Veterinária Brasileira, 2020
: Electrocardiographic markers have been used in people to classify arrhythmogenic risk. The aims of this study were to investigate electrocardiographic markers of conduction and repolarization in Boxers and non-Boxer dogs, and compare such findings ...
Elizabeth Regina Carvalho, Evandro Zacché, Michelli Fenerich, Aparecido Antônio Camacho, Julio P. Santos, Marlos G. Sousa   +5 more
doaj   +1 more source

Arrhythmic risk in elderly patients candidates to transcatheter aortic valve replacement. predicative role of repolarization temporal dispersion [PDF]

, 2019
Degenerative aortic valve stenosis (AS) is associated to ventricular arrhythmias and sudden cardiac death, as well as mental stress in specific patients. In such a context, substrate, autonomic imbalance as well as repolarization dispersion abnormalities ...
Crapanzano, Davide, DI IORIO, Claudia, Fabietti, Marcella, Magri', Damiano, Mariani, MARCO VALERIO, Mastropietri, Fabiola, Moscucci, Federica, Parrotta, Ilaria, Piccirillo, Gianfranco, Sabatino, Teresa, Salvi, Nicolo', Vespignani, Giulia   +11 more
core   +1 more source

Early screening of hypertension and cardiac dysautonomia in each hypertensive is needed-inference from a study of QTc interval in Gujarat, India

International Journal of Preventive Medicine, 2018
Background: Hypertension (HTN) is linked to cardiac dysautonomia that can end up as life-threatening arrhythmias. The same can be screened by simple electrocardiogram (ECG)-based QTc (QT corrected for heart rate) interval which indicates repolarization ...
Jayesh Dalpatbhai Solanki, Bhakti P Gadhavi, Amit H Makwana, Hemant B Mehta, Chinmay J Shah, Pradnya A Gokhale   +5 more
doaj   +1 more source

Incorporating Latent Variables Using Nonnegative Matrix Factorization Improves Risk Stratification in Brugada Syndrome

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background A combination of clinical and electrocardiographic risk factors is used for risk stratification in Brugada syndrome. In this study, we tested the hypothesis that the incorporation of latent variables between variables using nonnegative matrix ...
Gary Tse, Jiandong Zhou, Sharen Lee, Tong Liu, George Bazoukis, Panagiotis Mililis, Ian C. K. Wong, Cheng Chen, Yunlong Xia, Tsukasa Kamakura, Takeshi Aiba, Kengo Kusano, Qingpeng Zhang, Konstantinos P. Letsas   +13 more
doaj   +1 more source

Changes of repolarization parameters after left bundle branch area pacing and the association with echocardiographic response in heart failure patients

Frontiers in Physiology, 2022
Background: Left bundle branch area pacing (LBBAP) has become a safe and effective option for heart failure (HF) patients indicated for cardiac resynchronization therapy (CRT) and/or ventricular pacing, yet the response rate was only 70%.
Yao Li, Wenzhao Lu, Qingyun Hu, Chendi Cheng, Jinxuan Lin, Yu’an Zhou, Ruohan Chen, Yan Dai, Keping Chen, Shu Zhang   +9 more
doaj   +1 more source

Restricting excessive cardiac action potential and QT prolongation: a vital role for IKs in human ventricular muscle [PDF]

, 2005
Background - Although pharmacological block of the slow, delayed rectifier potassium current (I-Ks) by chromanol 293B, L-735,821, or HMR-1556 produces little effect on action potential duration (APD) in isolated rabbit and dog ventricular myocytes, the ...
Biliczki, Péter, Bitay, Miklós, Bogáts, Gábor, Jost, Norbert, Lathrop, David A., Lengyel, Csaba Attila, Nagy, Zsolt, Papp, Gyula, Takács, János, Varró, András, Virág, László   +10 more
core   +1 more source