Results 31 to 40 of about 100,632 (325)

Changes of repolarization parameters after left bundle branch area pacing and the association with echocardiographic response in heart failure patients

Frontiers in Physiology, 2022
Background: Left bundle branch area pacing (LBBAP) has become a safe and effective option for heart failure (HF) patients indicated for cardiac resynchronization therapy (CRT) and/or ventricular pacing, yet the response rate was only 70%.
Yao Li, Wenzhao Lu, Qingyun Hu, Chendi Cheng, Jinxuan Lin, Yu’an Zhou, Ruohan Chen, Yan Dai, Keping Chen, Shu Zhang   +9 more
doaj   +1 more source

Targeting lipid metabolism to overcome EMT-associated drug resistance via integrin β3/FAK pathway and tumor-associated macrophage repolarization using legumain-activatable delivery

Theranostics, 2019
Epithelial-mesenchymal transition (EMT) is closely associated with the development of drug resistance. Lipid metabolism plays an important role in EMT.
Hongyue Jin, Yang He, Pengfei Zhao, Ying Hu, Jin Tao, Jiang Chen, Yongzhuo Huang   +6 more
semanticscholar   +1 more source

Effects of Heart Rate on the Pump Function and Electrophysiological Characteristics of the Heart in the Frog Rana temporaria [PDF]

International Journal of Biomedicine, 2017
The aim of the study was to investigate the electrical activity and contractility of the heart ventricle in frogs Rana temporaria (n=14) under different heart rates.
Natalya A. Kibler, Vladimir P. Nuzhny, Svetlana V. Achmetzhynova, Dmitry N. Shmakov   +3 more
doaj   +1 more source

Mapping and Ablation of Ventricular Fibrillation Associated with Early Repolarization Syndrome.

Circulation, 2019
Background: We conducted a multicenter study to evaluate mapping and ablation of ventricular fibrillation (VF) substrates or VF triggers in early repolarization syndromes (ERS) or J-wave syndrome (JWS).
K. Nademanee, M. Haissaguerre, M. Hocini, A. Nogami, G. Cheniti, J. Duchâteau, E. Behr, M. Saba, R. Bokan, Qing Lou, Montawatt Amnueypol, R. Coronel, A. Khongphatthanayothin, G. Veerakul   +13 more
semanticscholar   +1 more source

Restricting excessive cardiac action potential and QT prolongation: a vital role for IKs in human ventricular muscle [PDF]

, 2005
Background - Although pharmacological block of the slow, delayed rectifier potassium current (I-Ks) by chromanol 293B, L-735,821, or HMR-1556 produces little effect on action potential duration (APD) in isolated rabbit and dog ventricular myocytes, the ...
Biliczki, Péter, Bitay, Miklós, Bogáts, Gábor, Jost, Norbert, Lathrop, David A., Lengyel, Csaba Attila, Nagy, Zsolt, Papp, Gyula, Takács, János, Varró, András, Virág, László   +10 more
core   +1 more source

Increased Beat-to-Beat Variability of T-Wave Heterogeneity Measured From Standard 12-Lead Electrocardiogram Is Associated With Sudden Cardiac Death: A Case–Control Study

Frontiers in Physiology, 2020
IntroductionThe prognostic significance of beat-to-beat variability of spatial heterogeneity of repolarization measured from standard 12-lead ECG is not well-understood.MethodsWe measured the short-term variability of repolarization parameters, such as T-
Jenni J. Hekkanen, Tuomas V. Kenttä, Mira Anette E. Haukilahti, Janne T. Rahola, Lauri Holmström, Juha Vähätalo, Mikko P. Tulppo, Antti M. Kiviniemi, Lasse Pakanen, Lasse Pakanen, Olavi H. Ukkola, M. Juhani Junttila, Heikki V. Huikuri, Juha S. Perkiömäki   +13 more
doaj   +1 more source

Ionic current changes underlying action potential repolarization responses to physiological pacing and adrenergic stimulation in adult rat ventricular myocytes

Physiological Reports, 2023
This study aimed to simulate ventricular responses to elevations in myocyte pacing and adrenergic stimulation using a novel electrophysiological rat model and investigate ion channel responses underlying action potential (AP) modulations.
Luke A. Howlett, Harley Stevenson‐Cocks, Michael A. Colman, Matthew K. Lancaster, Alan P. Benson   +4 more
doaj   +1 more source

Fast inactivation in Shaker K+ channels. Properties of ionic and gating currents. [PDF]

, 1998
Fast inactivating Shaker H4 potassium channels and nonconducting pore mutant Shaker H4 W434F channels have been used to correlate the installation and recovery of the fast inactivation of ionic current with changes in the kinetics of gating current known
Bezanilla, F, Olcese, R, Roux, MJ, Stefani, E, Toro, L   +4 more
core   +3 more sources

Comparison of Electrocardiographic Repolarization Patterns between Hypogonad Males and Normal Subjects

Annals of Noninvasive Electrocardiology, 2003
Background: There is a significant difference in repolarization on the surface ECG between men and women. The effect of testosterone on repolarization of myocardium may provide a basis for the physiological and pathophysiological importance of these ...
Ata Kirilmaz, Erol Bolu, Fethi Kilicaslan, Kursad Erinc, Mehmet Uzun, Ersoy Isik, Metin Ozata, Caglayan Ozdemir, Ertan Demirtas   +8 more
doaj   +1 more source

Dynamics of conduction blocks in a model of paced cardiac tissue [PDF]

, 2005
We study numerically the dynamics of conduction blocks using a detailed electrophysiological model. We find that this dynamics depends critically on the size of the paced region.
C. H. Luo, C. H. Luo, Hervé Henry, J. M. Pastore, M. Guevara, M. Pressler, Wouter-Jan Rappel, Z. Qu   +7 more
core   +1 more source