Results 231 to 240 of about 7,567,038 (395)

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Enhanced ADCC Activity of a C-Terminal Lysine Variant of an IgG₁ Antibody Driven by N-Linked MAN5 Glycan Using a Reporter Gene Assay. [PDF]

Antibodies (Basel)
Hsieh MC, Dorofejeva K, Zhang J, Vy DL, Qian J, Matathia AM, Blanc T, Li CR, Parekh BS.   +8 more
europepmc   +1 more source

Development of a reporter gene method to measure the bioactivity of anti-CD38 × CD3 bispecific antibody. [PDF]

Antib Ther, 2021
Xiong H, Luo F, Zhou P, Yi J.
europepmc   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

A Reporter Gene Assay for Measuring the Biological Activity of PEGylated Recombinant Human Growth Hormone. [PDF]

Molecules
Hu S, Zhang X, Li Y, Li J, Wang Y, Liang C.   +5 more
europepmc   +1 more source

Reporter gene systems for the identification and characterization of cancer stem cells. [PDF]

World J Stem Cells, 2021
Salinas-Jazmín N, Rosas-Cruz A, Velasco-Velázquez M.   +2 more
europepmc   +1 more source

The CD11b promoter directs high-level expression of reporter genes in macrophages in transgenic mice [published erratum appears in Blood 1995 Apr 1;85(7):1983] [PDF]

, 1995
Suzan Dziennis, RA Van Etten, HL Pahl, David L. Morris, TL Rothstein, CM Blosch, RM Perlmutter, Daniel G. Tenen   +7 more
openalex   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Covalent ¹⁸F-Radiotracers for SNAPTag: A New Toolbox for Reporter Gene Imaging. [PDF]

Pharmaceuticals (Basel), 2021
Stotz S, Bowden GD, Cotton JM, Pichler BJ, Maurer A.   +4 more
europepmc   +1 more source

MicroRNA-22 Regulates Smooth Muscle Cell Differentiation From Stem Cells by Targeting Methyl CpG-Binding Protein 2 [PDF]

, 2015
Guanmei Wen, Hanqing Zhao, Jianhua Zhu, Le Anh Luong, Li Zhang, Qingzhong Xiao, Qishan Chen, Shu Ye, Tayyab Adeel Afzal, Xiaotian Yu, Yu X, Yuan Huang   +11 more
core   +1 more source