Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Development and Validation of Two Cell-Based Reporter-Gene Assays for Determining the Bioactivity of Recombinant Human Thyroid-Stimulating Hormone Pharmaceutical Products. [PDF]
MoleculesWang L, Gao J, Xu K, Li J, Liang C.
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A brief review of reporter gene imaging in oncolytic virotherapy and gene therapy. [PDF]
Mol Ther Oncolytics, 2021 Concilio SC, Russell SJ, Peng KW.
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613. Non-Invasive Imaging of Firefly Luciferase Reporter Gene Expression Following Intramuscular Injection of Plasmid in a Mouse Model of CLI [PDF]
, 2003 openalex +1 more source
Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1
Molecular and Cellular Biology, 1996 Jo A. Forsythe +6 more
semanticscholar +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
An improved reporter gene assay for evaluating the biological activity of recombinant human growth hormone. [PDF]
J Pharm AnalZhang X +10 more
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Analysis of Dip2B Expression in Adult Mouse Tissues Using the LacZ Reporter Gene. [PDF]
Curr Issues Mol Biol, 2021 Sah RK +9 more
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Proceedings of the National Academy of Sciences of the United States of America, 1995 O. Boussif +6 more
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