Results 61 to 70 of about 282,080 (169)

Some concers regarding the mass deportations of bessarabians to the USSR between 1940-1941

open access: yesAstra Salvensis, 2019
In this article, the author presents a general radiography of communist repressions in Soviet Bessarabia between 1940-1941. The author makes some considerations on the nature of these repressions.
Gheorghe Cazacu
doaj  

Retour sur la révolte du bassin minier. Les cinq leçons politiques d’un conflit social inédit

open access: yesL’Année du Maghreb, 2010
When it erupted in early 2008, nobody could foresee the extent to which the Gafsa miners’ revolt would develop. Limited initially to social and professional claims, the revolt gradually assumed a protest and political dimension, transforming the protests
Larbi Chouikha, Vincent Geisser
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Entrepreneuriat social et répression : la gestion du commerce populaire à Belo Horizonte

open access: yesBrésil(s)
Policies that confine street vendors to so-called popular shopping centers create an accumulation frontier, involving both public and private actors.
Tarcísio Perdigão Araújo Filho
doaj   +1 more source

La cultura de los espacios socialistas. Casas del Pueblo y Centros obreros en la Segunda República española

open access: yesCahiers de Civilisation Espagnole Contemporaine, 2015
This article analyzes the growth of the Socialist Party and its cultural practices in the Second Spanish Republic. It describes the activities of the «House´s People» and the appearance of tens of new newspapers connected to psoe and ugt.
Diego Caro Cancela
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

The REST remodeling complex protects genomic integrity during embryonic neurogenesis

open access: yeseLife, 2016
The timely transition from neural progenitor to post-mitotic neuron requires down-regulation and loss of the neuronal transcriptional repressor, REST.
Tamilla Nechiporuk   +6 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

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