Advanced Materials, EarlyView.This study develops a multifunctional CRISPR‐dCas9‐based OMV platform termed OMV‐C9I12, which facilitates the coexpression of CXCL9 and IL‐12 within tumor cells. This platform enhances T cell recruitment and activation, synergizes with anti‐PD‐1/PD‐L1 immunotherapy, and amplifies antitumor T cell immunity.
Hongjin Wang +22 more
wiley +1 more source
The operators controlled by the lambda phage repressor.
, 1968 Mark Ptashne, Nancy Hopkins
openalex +1 more source
Interactions between DNA-bound repressors govern regulation by the λ phage repressor [PDF]
, 1979 Alexander D. Johnson +2 more
openalex +1 more source
A Microfluidic Multiplex Sorter for Strain Development
Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.A new multiplex method for high‐throughput screening of yeast strains based on glucoamylase production is presented. Droplets containing single mutant yeast cells are incubated for enzyme production. A sorting platform divides mutants by their high‐ and mid‐activity levels.
Chiara Leal‐Alves +6 more
wiley +1 more source
A Repressible Alkaline Phosphatase in Neurospora crassa
, 1966 Joseph F. Nyc +2 more
openalex +1 more source
Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy
Advanced Therapeutics, EarlyView.This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar +7 more
wiley +1 more source
Mutations Affecting the Repressibility of Arginine Biosynthetic Enzymes in Sacchromyces cerevisiae [PDF]
, 1970 J. Béchet, Marcelle Grenson, J.M. Wiame
openalex +1 more source
Self‐Adjusting Engineered Probiotic for Targeted Tumor Colonization and Local Therapeutics Delivery
Advanced Science, EarlyView.Zou et al. developed an engineered strain of Escherichia coli Nissle 1917 with precise targeting abilities for colonization and on‐demand payload release. The engineered probiotic survives and embolizes tumors only in the presence of more than 5 mM L‐lactate. Furthermore, the introduction of an α‐hemolysin circuit enhances its anti‐tumor effect.
Zhen‐Ping Zou +8 more
wiley +1 more source
Release of Repressor Control of Ribonucleotide Reductase by Thymine Starvation
, 1965 Chitra Biswas +2 more
openalex +1 more source
Lac Operator Analogues: Bromodeoxyuridine Substitution in the lac Operator Affects the Rate of Dissociation of the lac Repressor [PDF]
, 1972 Syr-Yaung Lin, Arthur D. Riggs
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