Results 41 to 50 of about 483,350 (345)
World Journal of Stem Cells, 2015 Induced pluripotent stem cells (iPSCs) have been the focal point of ever increasing interest and scrutiny as they hold the promise of personalized regenerative medicine. However, creation of iPSCs is an inefficient process that requires forced expression of potentially oncogenic proteins.
Melissa, Popowski, Haley, Tucker
openaire +2 more sources
NINJA connects the co-repressor TOPLESS to jasmonate signalling
Nature, 2010 Jasmonoyl-isoleucine (JA-Ile) is a plant hormone that regulates a broad array of plant defence and developmental processes. JA-Ile-responsive gene expression is regulated by the transcriptional activator MYC2 that interacts physically with the jasmonate ...
L. Pauwels +16 more
semanticscholar +1 more source
Journal of Oral Microbiology, 2020 Objective Treponema denticola is involved in ‘chronic’ periodontitis pathogenesis. The mechanism underlying the regulation of the expression of its virulence factors, such as major surface protein (Msp) and prolyl-phenylalanine specific protease ...
Yuki Arai +5 more
doaj +1 more source
Transcriptional co-repressor function of the hippo pathway transducers YAP and TAZ.
Cell Reports, 2015 YAP (yes-associated protein) and TAZ are oncogenic transcriptional co-activators downstream of the Hippo tumor-suppressor pathway. However, whether YAP and/or TAZ (YAP/TAZ) engage in transcriptional co-repression remains relatively unexplored.
Min-chul Kim +3 more
semanticscholar +1 more source
The Wheat VRN2 Gene Is a Flowering Repressor Down-Regulated by Vernalization
Science, 2004 Plants with a winter growth habit flower earlier when exposed for several weeks to cold temperatures, a process called vernalization. We report here the positional cloning of the wheat vernalization gene VRN2, a dominant repressor of flowering that is ...
Liuling Yan +8 more
semanticscholar +1 more source
R2R3-MYB Transcription Factors Regulate Anthocyanin Biosynthesis in Grapevine Vegetative Tissues
Frontiers in Plant Science, 2020 Anthocyanins with important physiological functions mainly accumulate in grape berry, but teinturier grape cultivars can accumulate anthocyanins in both reproductive and vegetative tissues.
Sha Xie +7 more
doaj +1 more source
DEC2 modulates orexin expression and regulates sleep. [PDF]
, 2018 Adequate sleep is essential for physical and mental health. We previously identified a missense mutation in the human DEC2 gene (BHLHE41) leading to the familial natural short sleep behavioral trait.
Fu, Ying-Hui +7 more
core +1 more source
NagRBt Is a Pleiotropic and Dual Transcriptional Regulator in Bacillus thuringiensis
Frontiers in Microbiology, 2018 NagR, belonging to the GntR/HutC family, is a negative regulator that directly represses the nagP and nagAB genes, which are involved in GlcNAc transport and utilization in Bacillus subtilis.
Zhang-lei Cao +8 more
doaj +1 more source
A dominant repressor version of the tomatoSl-ERF.B3gene confers ethylene hypersensitivity via feedback regulation of ethylene signaling and response components [PDF]
, 2013 Ethylene Response Factors (ERFs) are downstream components of the ethylene signal transduction pathway, although their role in ethylene-dependent developmental processes remains poorly understood. As the ethylene-inducible tomato Sl-ERF.B3 has been shown
Achard +51 more
core +4 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source