Results 31 to 40 of about 340,279 (315)

Role of the Two-Component System CiaRH in the Regulation of Efflux Pump SatAB and Its Correlation with Fluoroquinolone Susceptibility

open access: yesMicrobiology Spectrum, 2022
Streptococcus suis is an important pathogen in both pigs and humans. Although the diseases associated with S. suis can typically be treated with antibiotics, such use has resulted in a sustained increase in drug resistance. Bacteria can sense and respond
Xia Yang   +7 more
doaj   +1 more source

Functional Mechanism of the Efflux Pumps Transcription Regulators From Pseudomonas aeruginosa Based on 3D Structures

open access: yesFrontiers in Molecular Biosciences, 2018
Bacterial antibiotic resistance is a worldwide health problem that deserves important research attention in order to develop new therapeutic strategies.
Karim Housseini B Issa   +2 more
doaj   +1 more source

The Enterococcus faecalis FabT Transcription Factor Regulates Fatty Acid Biosynthesis in Response to Exogeneous Fatty Acids

open access: yesFrontiers in Microbiology, 2022
The phospholipid acyl chains of Enterococcus faecalis can be derived either by de novo synthesis or by incorporation of exogenous fatty acids through the fatty acid kinase complex (Fak)-phosphate acyltransferase (PlsX) pathway.
Qi Zou   +4 more
doaj   +1 more source

NINJA connects the co-repressor TOPLESS to jasmonate signalling

open access: yesNature, 2010
Jasmonoyl-isoleucine (JA-Ile) is a plant hormone that regulates a broad array of plant defence and developmental processes. JA-Ile-responsive gene expression is regulated by the transcriptional activator MYC2 that interacts physically with the jasmonate ...
L. Pauwels   +16 more
semanticscholar   +1 more source

Investigation of the potential regulator proteins associated with the expression of major surface protein and dentilisin in Treponema denticola

open access: yesJournal of Oral Microbiology, 2020
Objective Treponema denticola is involved in ‘chronic’ periodontitis pathogenesis. The mechanism underlying the regulation of the expression of its virulence factors, such as major surface protein (Msp) and prolyl-phenylalanine specific protease ...
Yuki Arai   +5 more
doaj   +1 more source

RETRACTED: LacI-Family Transcriptional Regulator DagR Acts as a Repressor of the Agarolytic Pathway Genes in Streptomyces coelicolor A3(2)

open access: yesFrontiers in Microbiology, 2021
Actinobacteria utilize various polysaccharides in the soil as carbon source by degrading them via extracellular hydrolytic enzymes. Agarose, a marine algal polysaccharide composed of D-galactose and 3,6-anhydro-L-galactose (AHG), is one of the carbon ...
Maral Tsevelkhoroloo   +4 more
doaj   +1 more source

Transcriptional co-repressor function of the hippo pathway transducers YAP and TAZ.

open access: yesCell Reports, 2015
YAP (yes-associated protein) and TAZ are oncogenic transcriptional co-activators downstream of the Hippo tumor-suppressor pathway. However, whether YAP and/or TAZ (YAP/TAZ) engage in transcriptional co-repression remains relatively unexplored.
Min-chul Kim   +3 more
semanticscholar   +1 more source

The Wheat VRN2 Gene Is a Flowering Repressor Down-Regulated by Vernalization

open access: yesScience, 2004
Plants with a winter growth habit flower earlier when exposed for several weeks to cold temperatures, a process called vernalization. We report here the positional cloning of the wheat vernalization gene VRN2, a dominant repressor of flowering that is ...
Liuling Yan   +8 more
semanticscholar   +1 more source

Lac repressor at last [PDF]

open access: yesStructure, 1996
Crystal and cocrystal structures of the LacI and PurR repressors reveal a novel use of hinge alpha helices which bind in the minor groove of the operator and mediate transmission of the allosteric signals that modulate DNA-binding activity.
openaire   +2 more sources

Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb.

open access: yesCell, 2000
Ci/Gli zinc finger proteins mediate the transcriptional effects of Hedgehog protein signals. In Drosophila, Ci action as transcriptional repressor or activator is contingent upon Hedgehog-regulated, PKA-dependent proteolytic processing.
Baolin Wang, J. Fallon, P. Beachy
semanticscholar   +1 more source

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