Results 31 to 40 of about 264,694 (307)

A R2R3-MYB Transcription Factor, VvMYBC2L2, Functions as a Transcriptional Repressor of Anthocyanin Biosynthesis in Grapevine (Vitis vinifera L.)

Molecules, 2018
In grapevine, the MYB transcription factors play an important role in the flavonoid pathway. Here, a R2R3-MYB transcription factor, VvMYBC2L2, isolated from Vitis vinifera cultivar Yatomi Rose, may be involved in anthocyanin biosynthesis as a ...
Ziguo Zhu, Guirong Li, Li Liu, Qingtian Zhang, Zhen Han, Xuesen Chen, Bo Li   +6 more
doaj   +1 more source

Role of the Two-Component System CiaRH in the Regulation of Efflux Pump SatAB and Its Correlation with Fluoroquinolone Susceptibility

Microbiology Spectrum, 2022
Streptococcus suis is an important pathogen in both pigs and humans. Although the diseases associated with S. suis can typically be treated with antibiotics, such use has resulted in a sustained increase in drug resistance. Bacteria can sense and respond
Xia Yang, Wei Peng, Ningning Wang, Beibei Dou, Fengming Yang, Huanchun Chen, Fangyan Yuan, Weicheng Bei   +7 more
doaj   +1 more source

Functional Mechanism of the Efflux Pumps Transcription Regulators From Pseudomonas aeruginosa Based on 3D Structures

Frontiers in Molecular Biosciences, 2018
Bacterial antibiotic resistance is a worldwide health problem that deserves important research attention in order to develop new therapeutic strategies.
Karim Housseini B Issa, Gilles Phan, Isabelle Broutin   +2 more
doaj   +1 more source

The Enterococcus faecalis FabT Transcription Factor Regulates Fatty Acid Biosynthesis in Response to Exogeneous Fatty Acids

Frontiers in Microbiology, 2022
The phospholipid acyl chains of Enterococcus faecalis can be derived either by de novo synthesis or by incorporation of exogenous fatty acids through the fatty acid kinase complex (Fak)-phosphate acyltransferase (PlsX) pathway.
Qi Zou, Huijuan Dong, Lei Zhu, John E. Cronan, John E. Cronan   +4 more
doaj   +1 more source

Investigation of the potential regulator proteins associated with the expression of major surface protein and dentilisin in Treponema denticola

Journal of Oral Microbiology, 2020
Objective Treponema denticola is involved in ‘chronic’ periodontitis pathogenesis. The mechanism underlying the regulation of the expression of its virulence factors, such as major surface protein (Msp) and prolyl-phenylalanine specific protease ...
Yuki Arai, Yuichiro Kikuchi, Kazuko Okamoto-Shibayama, Eitoyo Kokubu, Seikou Shintani, Kazuyuki Ishihara   +5 more
doaj   +1 more source

RETRACTED: LacI-Family Transcriptional Regulator DagR Acts as a Repressor of the Agarolytic Pathway Genes in Streptomyces coelicolor A3(2)

Frontiers in Microbiology, 2021
Actinobacteria utilize various polysaccharides in the soil as carbon source by degrading them via extracellular hydrolytic enzymes. Agarose, a marine algal polysaccharide composed of D-galactose and 3,6-anhydro-L-galactose (AHG), is one of the carbon ...
Maral Tsevelkhoroloo, So Heon Shim, Chang-Ro Lee, Soon-Kwang Hong, Young-Soo Hong   +4 more
doaj   +1 more source

NagRBt Is a Pleiotropic and Dual Transcriptional Regulator in Bacillus thuringiensis

Frontiers in Microbiology, 2018
NagR, belonging to the GntR/HutC family, is a negative regulator that directly represses the nagP and nagAB genes, which are involved in GlcNAc transport and utilization in Bacillus subtilis.
Zhang-lei Cao, Tong-tong Tan, Yan-li Zhang, Lu Han, Xiao-yue Hou, Hui-yong Ma, Jun Cai, Jun Cai, Jun Cai   +8 more
doaj   +1 more source

R2R3-MYB Transcription Factors Regulate Anthocyanin Biosynthesis in Grapevine Vegetative Tissues

Frontiers in Plant Science, 2020
Anthocyanins with important physiological functions mainly accumulate in grape berry, but teinturier grape cultivars can accumulate anthocyanins in both reproductive and vegetative tissues.
Sha Xie, Yujuan Lei, Huawei Chen, Junnan Li, Huangzhao Chen, Huangzhao Chen, Zhenwen Zhang, Zhenwen Zhang   +7 more
doaj   +1 more source

The lac repressor

Comptes Rendus. Biologies, 2005
Few proteins have had such a strong impact on a field as the lac repressor has had in Molecular Biology. Over 40 years ago, Jacob and Monod [Genetic regulatory mechanisms in the synthesis of proteins, J. Mol. Biol. 3 (1961) 318] proposed a model for gene regulation, which survives essentially
openaire   +2 more sources

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source