Results 21 to 30 of about 264,694 (307)

Repressors of reprogramming

open access: yesWorld Journal of Stem Cells, 2015
Induced pluripotent stem cells (iPSCs) have been the focal point of ever increasing interest and scrutiny as they hold the promise of personalized regenerative medicine. However, creation of iPSCs is an inefficient process that requires forced expression of potentially oncogenic proteins.
Melissa, Popowski, Haley, Tucker
openaire   +2 more sources

Profiling of REST-dependent microRNAs reveals dynamic modes of expression

open access: yesFrontiers in Neuroscience, 2012
Multipotent neural stem cells (NSCs) possess the ability to self-renew and differentiate into both neurons and glia. However, the detailed mechanisms underlying NSC fate decisions are not well understood.
Zhengliang eGao   +2 more
doaj   +1 more source

A Gain-of-Function Mutant of IAA15 Inhibits Lateral Root Development by Transcriptional Repression of LBD Genes in Arabidopsis

open access: yesFrontiers in Plant Science, 2020
Lateral root development is known to be regulated by Aux/IAA-ARF modules in Arabidopsisthaliana. As components, several Aux/IAAs have participated in these Aux/IAA-ARF modules.
Sun Ho Kim   +8 more
doaj   +1 more source

A dominant repressor version of the tomatoSl-ERF.B3gene confers ethylene hypersensitivity via feedback regulation of ethylene signaling and response components [PDF]

open access: yes, 2013
Ethylene Response Factors (ERFs) are downstream components of the ethylene signal transduction pathway, although their role in ethylene-dependent developmental processes remains poorly understood. As the ethylene-inducible tomato Sl-ERF.B3 has been shown
Kesari, Ravi   +9 more
core   +1 more source

Interaction of Gal repressor with inducer and operator: induction of gal transcription from repressor-bound DNA

open access: yes, 1997
Gal repressor inhibits transcription from the gal promoter (P1) when it binds to the cognate operator (OE). The repression is relieved by the presence of the inducer D-galactose. Compared with its interaction with free repressor, D-galactose binds to the
Roy, Siddhartha   +3 more
core   +3 more sources

The GbsR Family of Transcriptional Regulators: Functional Characterization of the OpuAR Repressor

open access: yesFrontiers in Microbiology, 2018
Accumulation of compatible solutes is a common stress response of microorganisms challenged by high osmolarity; it can be achieved either through synthesis or import.
Stefanie Ronzheimer   +4 more
doaj   +1 more source

Overexpression of PvPin1, a Bamboo Homolog of PIN1-Type Parvulin 1, Delays Flowering Time in Transgenic Arabidopsis and Rice

open access: yesFrontiers in Plant Science, 2017
Because of the long and unpredictable flowering period in bamboo, the molecular mechanism of bamboo flowering is unclear. Recent study showed that Arabidopsis PIN1-type parvulin 1 (Pin1At) is an important floral activator and regulates floral transition ...
Zhigang Zheng   +5 more
doaj   +1 more source

A 314-bp SINE insertion in the ZNF2 promoter region may act as a repressor related to regulation of fat deposition in pigs

open access: yesJournal of Integrative Agriculture, 2023
Retrotransposons, a type of DNA fragment that can mobilize itself on genome, can generate genetic variations and develop for molecular markers based on the insertion polymorphism.
Hao GU   +8 more
doaj   +1 more source

Allelic expression mapping across cellular lineages to establish impact of non‐coding SNPs

open access: yesMolecular Systems Biology, 2014
Most complex disease‐associated genetic variants are located in non‐coding regions and are therefore thought to be regulatory in nature. Association mapping of differential allelic expression (AE) is a powerful method to identify SNPs with direct cis ...
Veronique Adoue   +16 more
doaj   +1 more source

Ten-eleven translocation proteins (TETs): tumor suppressors or tumor enhancers?

open access: yesFrontiers in Bioscience-Landmark, 2021
The epigenetic memory stored in the dynamic modifications, such as base modifications of cytosine (C) in DNA, including methylation/hydroxymethylation/demethylation, causes heritable phenotypes via regulating gene expression without alteration of DNA ...
Cuili Ma   +5 more
doaj   +1 more source

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