Multiple binding sites for transcriptional repressors can produce regular bursting and enhance noise suppression [PDF]
, 2017 Cells may control fluctuations in protein levels by means of negative autoregulation, where transcription factors bind DNA sites to repress their own production.
Lengyel, Iván M., Morelli, Luis G.
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Sequence Dependence of Transcription Factor-Mediated DNA Looping [PDF]
, 2012 DNA is subject to large deformations in a wide range of biological processes. Two key examples illustrate how such deformations influence the readout of the genetic information: the sequestering of eukaryotic genes by nucleosomes, and DNA looping in ...
Barry +62 more
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What makes the lac-pathway switch: identifying the fluctuations that trigger phenotype switching in gene regulatory systems [PDF]
, 2014 Multistable gene regulatory systems sustain different levels of gene expression under identical external conditions. Such multistability is used to encode phenotypic states in processes including nutrient uptake and persistence in bacteria, fate ...
Berg, Johannes +3 more
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The GbsR Family of Transcriptional Regulators: Functional Characterization of the OpuAR Repressor
Frontiers in Microbiology, 2018 Accumulation of compatible solutes is a common stress response of microorganisms challenged by high osmolarity; it can be achieved either through synthesis or import.
Stefanie Ronzheimer +4 more
doaj +1 more source
Negative feedback control of jasmonate signaling by an alternative splice variant of JAZ10 [PDF]
, 2013 The plant hormone jasmonate (JA) activates gene expression by promoting ubiquitin-dependent degradation of JAZ transcriptional repressor proteins. A key feature of all JAZ proteins is the highly conserved Jas motif, which mediates both JAZ degradation ...
Campos, Marcelo L. +7 more
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Journal of Integrative Agriculture, 2023 Retrotransposons, a type of DNA fragment that can mobilize itself on genome, can generate genetic variations and develop for molecular markers based on the insertion polymorphism.
Hao GU +8 more
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Optimizing periodicity and polymodality in noise-induced genetic oscillators [PDF]
, 2011 Many cellular functions are based on the rhythmic organization of biological processes into self-repeating cascades of events. Some of these periodic processes, such as the cell cycles of several species, exhibit conspicuous irregularities in the form of
A. Sveiczer +6 more
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Frontiers in Plant Science, 2017 Because of the long and unpredictable flowering period in bamboo, the molecular mechanism of bamboo flowering is unclear. Recent study showed that Arabidopsis PIN1-type parvulin 1 (Pin1At) is an important floral activator and regulates floral transition ...
Zhigang Zheng +5 more
doaj +1 more source
DNA looping: the consequences and its control [PDF]
, 2006 The formation of DNA loops by proteins and protein complexes is ubiquitous to many fundamental cellular processes, including transcription, recombination, and replication.
Ackers +45 more
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Crystallization and preliminary crystallographic analysis of dUTPase from the helper phage Φ11 of Staphylococcus aureus [PDF]
, 2011 Staphylococcus aureus superantigen-carrying pathogenicity islands (SaPIs) have a determinant role in spreading virulence genes among bacterial populations that constitute a major health hazard.
Bendes, Ábris +5 more
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