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Gene Regulation and Transcriptomics [PDF]
Borrelia (Borreliella) burgdorferi, along with closely related species, is the etiologic agent of Lyme disease. The spirochete subsists in an enzootic cycle that encompasses acquisition from a vertebrate host to a tick vector and transmission from a tick vector to a vertebrate host.
Samuels, D. Scott +8 more
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Strigolactone-Mediated Trehalose Enhances Salt Resistance in Tomato Seedlings
Strigolactones (SLs) are newly discovered plant hormones that modulate a variety of physiological and biochemical processes and plant stress responses.
Xuefang Lu +6 more
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Master regulator genes and their impact on major diseases [PDF]
Master regulator genes (MRGs) have become a hot topic in recent decades. They not only affect the development of tissue and organ systems but also play a role in other signal pathways by regulating additional MRGs.
Wanwan Cai +7 more
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Novel Roles of SPATULA in the Control of Stomata and Trichome Number, and Anthocyanin Biosynthesis
The bHLH transcription factor SPATULA (SPT) has been identified as a regulator during different stages of Arabidopsis development, including the control of leaf size. However, the mechanism via which it performs this function has not been elucidated.
Judith Jazmin Bernal-Gallardo +3 more
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Regulation of the Globin Genes [PDF]
The a- and b-globin gene clusters are subject to several levels of regulation. They are expressed exclusively in the erythroid cells, only during defined periods of development and in a perfectly tuned way, assuring, at any stage of ontogeny, a correct balance in the availability of a- and b-globin chains for hemoglobin assembling. Such a tight control
Cao A, MOI, PAOLO
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Gene Regulatory Network Inferences Using a Maximum-Relevance and Maximum-Significance Strategy. [PDF]
Recovering gene regulatory networks from expression data is a challenging problem in systems biology that provides valuable information on the regulatory mechanisms of cells.
Wei Liu, Wen Zhu, Bo Liao, Xiangtao Chen
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Over 170 RNA modifications have been identified after transcriptions, involving in regulation of RNA splicing, processing, translation and decay. Growing evidence has unmasked the crucial role of N6-methyladenosine (m6A) in cancer development and ...
Zhanzhan Li +5 more
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Background Ankylosing spondylitis (AS) is one of the most common immune-mediated arthritic diseases worldwide. Despite considerable efforts to elucidate its pathogenesis, the molecular mechanisms underlying AS are still not fully understood.
Han Wang +6 more
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Summary: Recent evidence demonstrates that colon cancer stem cells (CSCs) can generate neurons that synapse with tumor innervating fibers required for tumorigenesis and disease progression. Greater understanding of the mechanisms that regulate CSC driven
Joseph L. Regan +15 more
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The prophage-encoded transcriptional regulator AppY has pleiotropic effects on E. coli physiology.
Bacterial genome diversity is influenced by prophages, which are viral genomes integrated into the bacterial chromosome. Most prophage genes are silent but those that are expressed can provide unexpected properties to their host. Using as a model E. coli
Naoual Derdouri +4 more
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