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Gene Regulation and Transcriptomics [PDF]

open access: yesCurrent Issues in Molecular Biology, 2021
Borrelia (Borreliella) burgdorferi, along with closely related species, is the etiologic agent of Lyme disease. The spirochete subsists in an enzootic cycle that encompasses acquisition from a vertebrate host to a tick vector and transmission from a tick vector to a vertebrate host.
Samuels, D. Scott   +8 more
openaire   +2 more sources

Strigolactone-Mediated Trehalose Enhances Salt Resistance in Tomato Seedlings

open access: yesHorticulturae, 2023
Strigolactones (SLs) are newly discovered plant hormones that modulate a variety of physiological and biochemical processes and plant stress responses.
Xuefang Lu   +6 more
doaj   +1 more source

Master regulator genes and their impact on major diseases [PDF]

open access: yesPeerJ, 2020
Master regulator genes (MRGs) have become a hot topic in recent decades. They not only affect the development of tissue and organ systems but also play a role in other signal pathways by regulating additional MRGs.
Wanwan Cai   +7 more
doaj   +2 more sources

Novel Roles of SPATULA in the Control of Stomata and Trichome Number, and Anthocyanin Biosynthesis

open access: yesPlants, 2023
The bHLH transcription factor SPATULA (SPT) has been identified as a regulator during different stages of Arabidopsis development, including the control of leaf size. However, the mechanism via which it performs this function has not been elucidated.
Judith Jazmin Bernal-Gallardo   +3 more
doaj   +1 more source

Regulation of the Globin Genes [PDF]

open access: yesPediatric Research, 2002
The a- and b-globin gene clusters are subject to several levels of regulation. They are expressed exclusively in the erythroid cells, only during defined periods of development and in a perfectly tuned way, assuring, at any stage of ontogeny, a correct balance in the availability of a- and b-globin chains for hemoglobin assembling. Such a tight control
Cao A, MOI, PAOLO
openaire   +3 more sources

Gene Regulatory Network Inferences Using a Maximum-Relevance and Maximum-Significance Strategy. [PDF]

open access: yesPLoS ONE, 2016
Recovering gene regulatory networks from expression data is a challenging problem in systems biology that provides valuable information on the regulatory mechanisms of cells.
Wei Liu, Wen Zhu, Bo Liao, Xiangtao Chen
doaj   +1 more source

Molecular characterization, clinical relevance and immune feature of m7G regulator genes across 33 cancer types

open access: yesFrontiers in Genetics, 2022
Over 170 RNA modifications have been identified after transcriptions, involving in regulation of RNA splicing, processing, translation and decay. Growing evidence has unmasked the crucial role of N6-methyladenosine (m6A) in cancer development and ...
Zhanzhan Li   +5 more
doaj   +1 more source

Screening and identification of key chromatin regulator biomarkers for ankylosing spondylitis and drug prediction: evidence from bioinformatics analysis

open access: yesBMC Musculoskeletal Disorders, 2023
Background Ankylosing spondylitis (AS) is one of the most common immune-mediated arthritic diseases worldwide. Despite considerable efforts to elucidate its pathogenesis, the molecular mechanisms underlying AS are still not fully understood.
Han Wang   +6 more
doaj   +1 more source

Identification of a neural development gene expression signature in colon cancer stem cells reveals a role for EGR2 in tumorigenesis

open access: yesiScience, 2022
Summary: Recent evidence demonstrates that colon cancer stem cells (CSCs) can generate neurons that synapse with tumor innervating fibers required for tumorigenesis and disease progression. Greater understanding of the mechanisms that regulate CSC driven
Joseph L. Regan   +15 more
doaj   +1 more source

The prophage-encoded transcriptional regulator AppY has pleiotropic effects on E. coli physiology.

open access: yesPLoS Genetics, 2023
Bacterial genome diversity is influenced by prophages, which are viral genomes integrated into the bacterial chromosome. Most prophage genes are silent but those that are expressed can provide unexpected properties to their host. Using as a model E. coli
Naoual Derdouri   +4 more
doaj   +1 more source

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