Inferring a Transcriptional Regulatory Network from Gene Expression Data Using Nonlinear Manifold Embedding [PDF]
, 2010 Transcriptional networks consist of multiple regulatory layers corresponding to the activity of global regulators, specialized repressors and activators of transcription as well as proteins and enzymes shaping the DNA template.
Hossein Zare +2 more
core +7 more sources
Regulation of genes involved in carnitine homeostasis by PPARa across different species (rat, mouse, pig, cattle, chicken, and human) [PDF]
, 2012 Recent studies in rodents convincingly demonstrated that PPAR-alpha is a key regulator of genes involved in carnitine homeostasis, which serves as a reasonable explanation for the phenomenon that energy deprivation and fibrate treatment, both of which ...
Egeri, Leonie +4 more
core +1 more source
Brassinosteroid-Regulated Gene Expression [PDF]
Plant Physiology, 2002 Abstract Major brassinosteroid (BR) effects such as BR-induced growth are mediated through genomic pathways because RNA synthesis inhibitors and protein synthesis inhibitors interfere with these processes. A limited number of BR-regulated genes have been identified hitherto. The majority of genes (such as BRU1, CycD3,Lin6, OPR3, and TRIP-
Altmann, Thomas +2 more
openaire +4 more sources
Journal of General Virology, 1987 Introduction. The parvoviruses are among the smallest of the DNA animal viruses (Siegl et al., 1985). The genome is a linear single-stranded DNA of approximately 5 kb which is encapsidated in a naked icosahedral virion 20 to 26 nm in diameter. There are two or three capsid proteins which have overlapping amino acid sequences; the larger species have ...
K I, Berns, M A, Labow
openaire +2 more sources
CRP-cAMP mediates silencing of Salmonella virulence at the post-transcriptional level [PDF]
, 2018 Invasion of epithelial cells by Salmonella enterica requires expression of genes located in the pathogenicity island I (SPI-1). The expression of SPI-1 genes is very tightly regulated and activated only under specific conditions.
Balsalobre, Carlos +6 more
core +4 more sources
Analysis of a conserved cellulase transcriptional regulator reveals inducer-independent production of cellulolytic enzymes in Neurospora crassa. [PDF]
, 2013 Cellulose is recalcitrant to deconstruction to glucose for use in fermentation strategies for biofuels and chemicals derived from lignocellulose. In Neurospora crassa, the transcriptional regulator, CLR-2, is required for cellulolytic gene expression and
Coradetti, Samuel +2 more
core +2 more sources
Genetic Interaction of Aspergillus nidulans galR, xlnR and araR in Regulating D-Galactose and L-Arabinose Release and Catabolism Gene Expression. [PDF]
PLoS ONE, 2015 In Aspergillus nidulans, the xylanolytic regulator XlnR and the arabinanolytic regulator AraR co-regulate pentose catabolism. In nature, the pentose sugars D-xylose and L-arabinose are both main building blocks of the polysaccharide arabinoxylan.
Joanna E Kowalczyk +5 more
doaj +1 more source
PAIP1 regulates expression of immune and inflammatory response associated genes at transcript level in liver cancer cell [PDF]
PeerJ, 2023 Poly(A) binding protein interacting protein 1 (PAIP1) is a translation regulator and also regulate the decay of mRNA. PAIP1 has also been reported to be a marker of increased invasive potential of liver cancer. However, the roles and underlying molecular
Jianfeng Zheng +7 more
doaj +2 more sources
DISTILLER: a data integration framework to reveal condition dependency of complex regulons in Escherichia coli [PDF]
, 2009 We present DISTILLER, a data integration framework for the inference of transcriptional module networks. Experimental validation of predicted targets for the well-studied fumarate nitrate reductase regulator showed the effectiveness of our approach in ...
Lemmens, Karen +11 more
core +3 more sources
Frontiers in Microbiology, 2017 The heterotrophic marine bacterium Dinoroseobacter shibae utilizes aerobic respiration and anaerobic denitrification supplemented with aerobic anoxygenic photosynthesis for energy generation.
Elisabeth Härtig +7 more
doaj +1 more source