PLoS ONE, 2013 The composition of the cellulosomes (multi enzymatic complexes involved in the degradation of plant cell wall polysaccharides) produced by Clostridium cellulolyticum differs according to the growth substrate. In particular, the expression of a cluster of
Hamza Celik +8 more
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Plasmids manipulate bacterial behaviour through translational regulatory crosstalk.
PLoS Biology, 2023 Beyond their role in horizontal gene transfer, conjugative plasmids commonly encode homologues of bacterial regulators. Known plasmid regulator homologues have highly targeted effects upon the transcription of specific bacterial traits.
Catriona M A Thompson +13 more
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The Multifaceted Activity of the VirF Regulatory Protein in the Shigella Lifestyle [PDF]
, 2016 Shigella is a highly adapted human pathogen, mainly found in the developing world and causing a severe enteric syndrome. The highly sophisticated infectious strategy of Shigella banks on the capacity to invade the intestinal epithelial barrier and cause ...
Colonna, Bianca +4 more
core +3 more sources
The regulatory and transcriptional landscape associated with carbon utilization in a filamentous fungus. [PDF]
, 2020 Filamentous fungi, such as Neurospora crassa, are very efficient in deconstructing plant biomass by the secretion of an arsenal of plant cell wall-degrading enzymes, by remodeling metabolism to accommodate production of secreted enzymes, and by enabling ...
Benz, J Philipp +15 more
core +3 more sources
I-TRAP: A method to identify transcriptional regulator activated promoters
BMC Infectious Diseases, 2003 Background The differential expression of virulence genes is often used by microbial pathogens in adapting to the environment of their host. The differential expression of such sets of genes can be regulated by RNA polymerase sigma factors.
McLendon Molly M, Shinnick Thomas M
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ArgR is an essential local transcriptional regulator of the arcABC-operon in Streptococcus suis and crucial for biological fitness in acidic environment [PDF]
, 2011 Streptococcus suis is one of the most important pathogens in pigs and can also cause severe infections in humans. Despite its clinical relevance very little is known about the factors contributing to its virulence.
Benga, L. +6 more
core +2 more sources
Identification and characterization of a direct activator of a gene transfer agent
Nature Communications, 2019 Gene transfer agents (GTAs) are ‘domesticated’ bacteriophages that can transfer any genes between bacteria. Here, Paul Fogg identifies a protein that directly regulates transcription of GTA genes and whose expression is in turn controlled by a global ...
Paul C. M. Fogg
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OsRELA Regulates Leaf Inclination by Repressing the Transcriptional Activity of OsLIC in Rice
Frontiers in Plant Science, 2021 Leaf angle is one of the most important agronomic traits in rice, and changes in leaf angle can alter plant architecture to affect photosynthetic efficiency and thus determine grain yield. Therefore, it is important to identify key genes controlling leaf
Chen-li Zhu +8 more
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Agrobacterium tumefaciens estC, Encoding an Enzyme Containing Esterase Activity, Is Regulated by EstR, a Regulator in the MarR Family. [PDF]
PLoS ONE, 2016 Analysis of the A. tumefaciens genome revealed estC, which encodes an esterase located next to its transcriptional regulator estR, a regulator of esterase in the MarR family.
Surawach Rittiroongrad +4 more
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Inferred expression regulator activities suggest genes mediating cardiometabolic genetic signals.
PLoS Computational Biology, 2021 Expression QTL (eQTL) analyses have suggested many genes mediating genome-wide association study (GWAS) signals but most GWAS signals still lack compelling explanatory genes.
Jason W Hoskins +7 more
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