Results 11 to 20 of about 264,694 (307)
Copper is broadly toxic to bacteria. As such, bacteria have evolved specialized copper export systems (cop operons) often consisting of a DNA-binding/copper-responsive regulator (which can be a repressor or activator), a copper chaperone, and a copper ...
Henrik O’Brien +5 more
doaj +1 more source
The Transcriptional Repressor Orphan Nuclear Receptor TLX Is Responsive to Caffeine and Istradefylline [PDF]
The orphan nuclear receptor TLX is expressed almost exclusively in neural stem cells. TLX acts as an essential factor for neural stem cell survival and is hence considered as a promising drug target in neurodegeneration.
Pascal, Heitel +10 more
core +2 more sources
Two Retrotransposon Elements in Intron of Porcine BMPR1B Is Associated with Phenotypic Variation
It has been established that through binding to bone morphogenetic proteins (BMPs), bone morphogenetic protein receptor I B (BMPR1B) can mediate transforming growth factor β (TGF-β) signal transduction, and is involved in the regulation of several ...
Chenglin Chi +9 more
doaj +1 more source
The MYB (myeloblastosis) superfamily constitutes one of the most abundant transcription factors (TFs) regulating various biological processes in plants. However, the molecular characteristics and functions of MYB TFs in pitaya remain unclear. To date, no
Fangfang Xie +8 more
doaj +1 more source
AlkB monooxygenases in bacteria are responsible for the hydroxylation of medium- and long-chain n-alkanes. In this study, one CrgA protein of Pseudomonas aeruginosa SJTD-1, a member of LysR family, was proved to regulate AlkB2 monooxygenase and the ...
Nannan Ji +4 more
doaj +1 more source
Repressor of Phage 16-3 with Altered Binding Specificity Indicates Spatial Differences in Repressor-Operator Complexes [PDF]
The C repressor protein of phage 16-3, which is required for establishing and maintaining lysogeny, recognizes structurally different operators which differ by 2 bp in the length of the spacer between the conserved palindromic sequences.
Papp, P. Péter +2 more
core +1 more source
Kaiso is a genome-wide repressor of transcription that is essential for amphibian development [PDF]
DNA methylation in animals is thought to repress transcription via methyl-CpG specific binding proteins, which recruit enzymatic machinery promoting the formation of inactive chromatin at targeted loci.
Richard R. Meehan +13 more
core +1 more source
Adipose thermogenesis plays a pivotal role in whole‐body metabolic homeostasis. Although transcriptional mechanisms that promote thermogenesis are extensively studied, the negative regulatory network is still poorly understood. Here, a Krüppel‐associated
Lei Huang +3 more
doaj +1 more source
Role of the purine repressor hinge sequence in repressor function [PDF]
A protease-hypersensitive hinge sequence in Escherichia coli purine repressor (PurR) connects an N-terminal DNA-binding domain with a contiguous corepressor-binding domain. Binding of one molecule of dimeric repressor to operator DNA protects the hinge against proteolytic cleavage.
K Y, Choi, H, Zalkin
openaire +2 more sources
The DeoR-type transcriptional regulator SugR acts as a repressor for genes encoding the phosphoenolpyruvate: sugar phosphotransferase system (PTS) in Corynebacterium glutamicum [PDF]
Gaigalat L, Schlüter J-P, Hartmann M, et al. The DeoR-type transcriptional regulator SugR acts as a repressor for genes encoding the phosphoenolpyruvate: sugar phosphotransferase system (PTS) in Corynebacterium glutamicum. BMC Molecular Biology. 2007;8(1)
Mormann, Sascha +14 more
core +1 more source

