Results 71 to 80 of about 382,695 (354)

Designer Gene Networks: Towards Fundamental Cellular Control

, 2001
The engineered control of cellular function through the design of synthetic genetic networks is becoming plausible. Here we show how a naturally occurring network can be used as a parts list for artificial network design, and how model formulation leads ...
Ackers, Arkin, Barkai, Becksei, Bialek, Bray, Chen, Dickson, Elowitz, Endy, Gardner, Gillespie, Glass, Glass, Glass, Hammond, Harada, Harding, Hartwell, Hasty, Jacob, Johnson, Johnson, Kauffman, Keller, Lauffenburger, Lowman, McAdams, McAdams, McAdams, McClure, Meyer, Monod, Monod, Moran, Novak, Novak, Novick, Ohlendorf, Palsson, Ptaschne, Reinitz, Rozanov, Samoilov, Sancho, Savageau, Savageau, Savageau, Shea, Smolen, Sveiczer, Szafranski, Tyson, Villaverde, von Hippel, Wolf, Wong   +56 more
core   +1 more source

Novel and unscrutinized immune entities of the zebrafish gut

FEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil, Marine Mantel, Julia Soh, Serge Mostowy, Sylvia Brugman, Gilles Claude Vanwalleghem   +5 more
wiley   +1 more source

Estudos Sôbre Regulação Metabólica Contrôle de Síntese de Proteínas: V - Ação da Glicose na Regulação da Tirosina Alfa Ceto Glutarato Transaminase em Fígado de Rato

Revista Brasileira de Cancerologia, 2023
O presente trabalho demonstra que o efeito “repressor” da glicose sôbre TT no fígado não se apresenta se o animal fôr previamente tratado com 5-PU. Porém, o 5-FU não evita o efeito da glicose, se fôr administrado depois dêste glicidio.
Mauro C. Faria, F. G. Mello, P. Preza, H. C. Faria   +3 more
doaj   +1 more source

dUTPase based switch controls transfer of virulence genes in order to preserve integrity of the transferred mobile genetic elements [PDF]

, 2013
dUTPases ubiquitously regulate cellular dUTP levels to preserve genome integrity. Recently, several other cellular processes were reported to be controlled by dUTPases including the horizontal transfer of Staphylococcus aureus pathogenicity islands ...
Bendes, A., Besztercei, B., Leveles, I., Liliom, K., Nyíri, K., Németh-Pongrácz, V., Papp-Kádár, V., Pálinkás, H., Róna, G., Szabó, J. E., Tóth, J., Vértessy G., Beáta, Zagyva, I.   +12 more
core   +1 more source

Specificity determinants for the interaction of lambda repressor and P22 repressor dimers. [PDF]

Genes & Development, 1994
The related phage lambda and phage P22 repressors each bind cooperatively to adjacent and separated operator sites, an interaction that involves a pair of repressor dimers. The specificities of these interactions differ: Each dimer interacts with its own type but not with dimers of the heterologous repressor.
Ann Hochschild, L A Cheatham, Frederick W. Whipple, N H Kuldell   +3 more
openaire   +3 more sources

Protein kinase FAM20C—when subcellular localization matters

FEBS Letters, EarlyView.
FAM20C is a Golgi‐resident kinase that phosphorylates proteins along the entire secretory pathway. The presence of potential FAM20C substrates in the cytoplasm or nucleus raises the question of how the kinase and its substrates encounter each other. Protein kinases achieve signaling specificity through consensus sequence recognition and subcellular ...
Francesca Noventa, Mauro Salvi
wiley   +1 more source

The N-terminal domain of the repressor of Staphylococcus aureus phage Φ11 possesses an unusual dimerization ability and DNA binding affinity. [PDF]

PLoS ONE, 2014
Bacteriophage Φ11 uses Staphylococcus aureus as its host and, like lambdoid phages, harbors three homologous operators in between its two divergently oriented repressor genes. None of the repressors of Φ11, however, showed binding to all three operators,
Anindya Biswas, Sukhendu Mandal, Subrata Sau   +2 more
doaj   +1 more source

Construction and utilisation of a bidirectional reporter vector in the analysis of two nod-boxes in of Rhizobium loti : a thesis presented in partial fulfilment of the requirements for the Degree of Master of Science in Molecular Genetics at Massey University [PDF]

, 1993
The nod-box is a 47bp cis-acting regulatory region which has been conserved amongst every species of Rhizobium studied to date. In species such as R. meliloti and R.
Parry, Simon Keith
core  

Compositionality, stochasticity and cooperativity in dynamic models of gene regulation

, 2007
We present an approach for constructing dynamic models for the simulation of gene regulatory networks from simple computational elements. Each element is called a ``gene gate'' and defines an input/output-relationship corresponding to the binding and ...
Alberts B, Andrew Phillips, Blossey R, Bundschuh R, Cherry JL, De Jong H, Fall CP, Freidlin MI, Kim J, Lee Deville RE, Luca Cardelli, Milner R, Müller S, Phillips A, Priami C, Ralf Blossey, Smolen P, Thomas R, Thomas R, Van Kampen NG   +19 more
core   +2 more sources

Nucleotide sequence and mutational analysis of an immunity repressor gene from Bacillus subtilis temperate phage ϕ105 [PDF]

, 1985
We have identified and sequenced a bacteriophage phi 105 gene encoding an immunity repressor, the first to be characterized from a temperate phage infecting a Gram-positive host.
De Smet, Bea, Dhaese, Patrick, Seurinck, Jozef, Van Montagu, Marc   +3 more
core   +2 more sources