Results 91 to 100 of about 115,119 (230)

Elucidating the Mechanism of Temporal Adaptation to Hydrogen Peroxide‐Induced Oxidative Stress in Corynebacterium glutamicum

Microbial Biotechnology, Volume 18, Issue 6, June 2025.
In this study, RNA‐seq was employed to investigate the temporal transcriptional response of C. glutamicum ATCC 13032 to external H2O2 at 720 mM (2.45% w/w). The results reveal significant changes in gene expression across multiple pathways, including peroxide scavenging, central metabolism, sulphur and iron metabolism, amino acid biosynthesis, and DNA ...
Chang Yu, Wenjing Hu, Xiaoyu Li, Yu Lei, Dandan Gao, Meng Wang, Ping Zheng, Yan Zhu, Jibin Sun   +8 more
wiley   +1 more source

Regulation of transcription elongation in response to osmostress [PDF]

, 1967
Cells trigger massive changes in gene expression upon environmental fluctuations. The Hog1 stress-activated protein kinase (SAPK) is an important regulator of the transcriptional activation program that maximizes cell fitness when yeast cells are exposed
Begley, Victoria Sarah, Böttcher, René, Cavero, Santiago, Chávez de Diego, Sebastián, Nadal, Eulàlia de, Posas, Francesc, Silva, Andrea, Solé, Carme   +7 more
core   +3 more sources

Harnessing promoter elements to enhance gene editing in plants: perspectives and advances

Plant Biotechnology Journal, Volume 23, Issue 5, Page 1375-1395, May 2025.
Summary Genome‐edited plants, endowed with climate‐smart traits, have been promoted as tools for strengthening resilience against climate change. Successful plant gene editing (GE) requires precise regulation of the GE machinery, a process controlled by the promoters, which drives its transcription through interactions with transcription factors (TFs ...
Nikita Gondalia, Luis Felipe Quiroz, Linyi Lai, Avinash Kumar Singh, Moman Khan, Galina Brychkova, Peter C. McKeown, Manash Chatterjee, Charles Spillane   +8 more
wiley   +1 more source

Engineering archaeal membrane‐spanning lipid GDGT biosynthesis in bacteria: Implications for early life membrane transformations

mLife, Volume 4, Issue 2, Page 193-204, April 2025.
Abstract Eukaryotes are hypothesized to be archaeal–bacterial chimeras. Given the different chemical structures of membrane phospholipids in archaea and bacteria, transformations of membranes during eukaryogenesis that led to the bacterial‐type membranes of eukaryotic cells remain a major conundrum.
Huahui Chen, Fengfeng Zheng, Xi Feng, Zijing Huang, Wei Yang, Chuanlun Zhang, Wenbin Du, Kira S. Makarova, Eugene V. Koonin, Zhirui Zeng   +9 more
wiley   +1 more source

Early genome erosion and internal phage-symbiont-host interaction in the endosymbionts of a cold-seep tubeworm

iScience, 2023
Summary: Endosymbiosis with chemosynthetic Gammaproteobacteria is widely recognized as an adaptive mechanism of siboglinid tubeworms, yet evolution of these endosymbionts and their driving forces remain elusive.
Zhao-Ming Gao, Ting Xu, Hua-Guan Chen, Rui Lu, Jun Tao, Hong-Bin Wang, Jian-Wen Qiu, Yong Wang   +7 more
doaj  

Distinct regions of the Swi5 and Ace2 transcription factors are required for specific gene activation [PDF]

, 1999
Swi5 and Ace2 are cell cycle-regulated transcription factors that activate expression of early G1-specific genes in Saccharomyces cerevisiae. Swi5 and Ace2 have zinc finger DNA-binding domains that are highly conserved, and the two proteins bind to the ...
McBride, Helen J., Stillman, David J., Yu, Yaxin   +2 more
core   +2 more sources

A core Plasmopara viticola effector attenuates the DNA‐binding activity of bZIP transcription factor to compromise plant immunity

The Plant Journal, Volume 122, Issue 2, April 2025.
SUMMARY Grapevine (Vitis vinifera L.) frequently faces challenges from various pathogens, among which Plasmopara viticola is the most devastating one hindering grape production. During infection, P. viticola secretes a series of effectors into host cells to manipulate plant immune responses. Here, an RXLR effector of P.
Jiaqi Liu, Tao Ma, Jianxiang Liang, Bohan Yang, Shuyun Chen, Xinlong Li, Wei Wu, Jiang Lu, Peining Fu   +8 more
wiley   +1 more source

In vitro binding of LexA repressor to DNA: evidence for the involvement of the amino-terminal domain. [PDF]

The EMBO Journal, 1986
Both the amino-terminal and the carboxy-terminal domain of the LexA repressor have been purified using the LexA protein autodigestion reaction at alkaline pH, which leads to the same specific products as the physiological RecA-catalyzed proteolysis of repressor.
Serge Hurstel, Michèle Granger-Schnarr, Manfred Schnarr, Michel Daune   +3 more
openaire   +3 more sources

The trans-activation domain of the sporulation response regulator Spo0A revealed by X-ray crystallography [PDF]

, 2000
Sporulation in Bacillus involves the induction of scores of genes in a temporally and spatially co-ordinated programme of cell development. Its initiation is under the control of an expanded two-component signal transduction system termed a phosphorelay.
Baldus J.M., Brown D.P., Buckner C.M., Buckner C.M., Busby S., Chung J.D., Cowtan K., Ferrari F.A., Fogh R.H., Green B.D., Grimsley J.K., Hatt J.K., Igarashi K., Ireton K., Kenney T.J., Kondo H., Kuldell N., Makino K., Martinez-Hackert E., Muchova K., Murshudov G.N., Olmedo G., Perego M., Satola S.W., Schyns G., Spiegelman G.B., Spiegelman G.B., Strauch M.A., Strauch M.A., Terwilliger T.C., Weir J., Wu H.-M., York K.   +32 more
core   +1 more source

Identification, characterization and classification of prokaryotic nucleoid‐associated proteins

Molecular Microbiology, Volume 123, Issue 3, Page 206-217, March 2025.
Nucleoid‐associated proteins (NAPs) structure DNA by either bending, wrapping, bridging, or forming protein filaments on the DNA. We review newly identified NAPs and provide a list of simple biochemical assays to study the DNA‐structuring properties of novel NAPs. Abstract Common throughout life is the need to compact and organize the genome.
Samuel Schwab, Remus T. Dame
wiley   +1 more source