Results 111 to 120 of about 115,119 (230)

Plastid HSP90C C‐terminal extension region plays a regulatory role in chaperone activity and client binding

The Plant Journal, Volume 119, Issue 5, Page 2288-2302, September 2024.
Significance Statement Phylogeny analysis on HSP90 family heat‐shock proteins revealed a highly conserved motif within the chloroplast HSP90C C‐terminal extension (CTE) region, especially in green plant lineage. Our analyses on CTE truncation mutants elucidated a critical role of the CTE in regulating the protein's chaperone activity and client binding
Bona Mu, Adheip Monikantan Nair, Rongmin Zhao   +2 more
wiley   +1 more source

A corepressor participates in LexA-independent regulation of error-prone polymerases in Acinetobacter

Microbiology, 2019
The DNA damage response of the multidrug-resistant pathogen Acinetobacter baumannii , which induces mutagenic UmuD′2C error-prone polymerases, differs from that of many bacteria.
Megan A. Peterson, Alison N. Grice, Janelle M. Hare   +2 more
semanticscholar   +1 more source

The Sulfolobus solfataricus radA paralogue sso0777 is DNA damage inducible and positively regulated by the Sta1 protein [PDF]

, 2007
Little is known about the regulation of the DNA damage-mediated gene expression in archaea. Here we report that the addition of actinomycin D to Sulfolobus solfataricus cultures triggers the expression of the radA paralogue sso0777.
Abella, M, Barbe, J, Campoy, S, Paytubi, S, Rodriquez, S, White, Malcolm Frederick   +5 more
core   +1 more source

Conquering new grounds: plant organellar C‐to‐U RNA editing factors can be functional in the plant cytosol

The Plant Journal, Volume 119, Issue 2, Page 895-915, July 2024.
Significance Statement We show that PPR‐type organelle RNA editing factors can principally also function in the plant cytosol but that their lack of targeting specificity likely restricts their occurrence in nature to chloroplasts and mitochondria. Our new approach of induced cytosolic expression will allow to much better characterize the RNA‐targeting
Mirjam Thielen, Béla Gärtner, Volker Knoop, Mareike Schallenberg‐Rüdinger, Elena Lesch   +4 more
wiley   +1 more source

DdiA, an XRE family transcriptional regulator, regulates a LexA-independent DNA damage response in Myxococcus xanthus

bioRxiv
Repair of DNA damage is essential for genome integrity. DNA damage elicits a DNA damage response (DDR) that includes error-free and error-prone, i.e. mutagenic, repair.
Jana Jung, Timo Glatter, Marco Herfurth, L. Søgaard‐Andersen   +3 more
semanticscholar   +1 more source

Transcription of theuvrDgene ofEscherichia coliis controlled by thelexArepressor and by attenuation [PDF]

Nucleic Acids Research, 1983
The nucleotide sequence of the control region and the presumptive N-terminal portion of the uvrD gene of Escherichia coli K-12 has been determined. The 1190 base pairs of DNA examined include the likely coding sequence for the first 258 amino acids of the uvrD protein.
Sidney R. Kushner, Alan M. Easton
openaire   +3 more sources

RecA and RadA Proteins of Brucella abortus Do Not Perform Overlapping Protective DNA Repair Functions following Oxidative Burst [PDF]

, 2006
Very little is known about the role of DNA repair networks in Brucella abortus and its role in pathogenesis. We investigated the roles of RecA protein, DNA repair, and SOS regulation in B. abortus.
Bellaire, Bryan H., Booth, Natha J., Elzer, Philip H., Ennis, Don G., Gee, Jason M., Kovach, Michael E., Roop, R. Martin II, Roux, Christelle M., Tsolis, Renee M.   +8 more
core   +2 more sources

Chemogenetic Tools in Focus: Proximity, Conformation, and Sterics

Chemistry–Methods, Volume 4, Issue 6, June 2024.
Chemogenetic tools have been widely applied to interrogate dynamic biological processes. They are genetically encoded systems that are controlled by user‐defined chemicals. In this review, chemogenetic tool designs for various biological applications are introduced and discussed.
Jiaqi Shen, Guanwei Zhou, Wenjing Wang
wiley   +1 more source

A flexible integrative approach based on random forest improves prediction of transcription factor binding sites [PDF]

, 2012
Transcription factor binding sites (TFBSs) are DNA sequences of 6-15 base pairs. Interaction of these TFBSs with transcription factors (TFs) is largely responsible for most spatiotemporal gene expression patterns.
Abeel, Afflerbach, Angarica, Bailey, Bart Hooghe, Bauer, Benos, Breiman, Bulyk, Burden, Calladine, Camenisch, Chen, Cho, Cordell, Davis, Dickerson, Ehret, Ernst, Frans van Roy, Friedel, Fujii, Fulton, Gama-Castro, Gardiner, Gartenberg, Gershenzon, Goodsell, Gorin, Gowrisankar, Greenbaum, Gunewardena, Hall, Hendrickson, Hu, Juo, Kajimura, Kaplan, Karas, Kel, Kim, Lavery, Lewis, Liu, Liu, Liu, Long, Lu, Lu, Lu, Lunetta, Man, Marco, Marinescu, Martinez-Hackert, Matys, Medina-Rivera, Meysman, Michel, Mokry, Morozov, Narang, Naughton, O'Flanagan, Olson, Paillard, Pan, Parker, Parvin, Pieter De Bleser, Ponomarenko, Portales-Casamar, Powell, Pudimat, Ramsey, Rohs, Rohs, Rohs, Ruiz, Satchwell, Schneider, Shakked, Sharon, Shi, Spolar, Stefan Broos, Stormo, Svozil, Thayer, Tomovic, Toro-Roman, Travers, Tullius, Wunderlich, Zhang, Zhang, Zhu   +96 more
core   +2 more sources

iChIP‐SILAC analysis identifies epigenetic regulators of CpG methylation of the p16INK4A gene

FEBS Letters, Volume 598, Issue 9, Page 1094-1109, May 2024.
iChIP‐SILAC identified DNMT1 and epigenetic regulators as proteins potentially interacting with a region of the p16INK4A gene that is CpG‐methylated in one allele in HCT116 cells. Among the identified proteins, DDX24 contributed to the CpG methylation by regulating the protein level of DNMT1.
Toshitsugu Fujita, Hodaka Fujii
wiley   +1 more source