In many organisms the expression levels of each gene are controlled by the activation levels of known "Transcription Factors" (TF). A problem of considerable interest is that of estimating the "Transcription Regulation Networks" (TRN) relating the TFs ...
James, Gareth M.+3 more
core +3 more sources
LexA is a well-known transcriptional repressor of DNA repair genes induced by DNA damage in Escherichia coli and other bacterial species. Recently, this paradigm—that LexA solely regulates the SOS response—has been challenged as studies reveal its ...
Rongchao He+4 more
doaj
Genome-wide transcriptome analysis of hydrogen production in the cyanobacterium Synechocystis: Towards the identification of new players [PDF]
International audienceWe report the development of new tools and methods for facile integration and meaningful representation of high throughput data generated by genome-wide analyses of the model cyanobacterium Synechocystis PCC6803, for future genetic ...
AUDE, Jean-Christophe+5 more
core +3 more sources
Homodimerization and heterodimerization requirements of Acinetobacter baumannii SOS response coregulators UmuDAb and DdrR revealed by two-hybrid analyses [PDF]
The multidrug-resistant pathogen Acinetobacter baumannii displays unusual control of its SOS mutagenesis genes, as it does not encode a LexA repressor, but instead employs the UmuDAb repressor and a small protein, DdrR, that is uniquely found in ...
Carrington, Jordan+3 more
core +1 more source
Consensus and meta-analysis regulatory networks for combining multiple microarray gene expression datasets [PDF]
Microarray data is a key source of experimental data for modelling gene regulatory interactions from expression levels. With the rapid increase of publicly available microarray data comes the opportunity to produce regulatory network models based on ...
Akaike+34 more
core +1 more source
Summary: Antimicrobial resistance poses a severe threat to human health and Pseudomonas aeruginosa stands out among the pathogens responsible for this emergency.
Filippo Vascon+11 more
doaj
The SOS Response Master Regulator LexA Regulates the Gene Transfer Agent of Rhodobacter capsulatus and Represses Transcription of the Signal Transduction Protein CckA [PDF]
Kevin S. Kuchinski+4 more
openalex +1 more source
"Activated"-RecA protein affinity chromatography of LexA repressor and other SOS-regulated proteins. [PDF]
Nancy E. Freitag, Kathleen Mc Entee
openalex +1 more source
SOS induction in Escherichia coli by single-stranded DNA of mutant filamentous phage: monitoring by cleavage of LexA repressor [PDF]
Nahoko Higashitani+2 more
openalex +1 more source
SOS induction in mycobacteria: analysis of the DNA‐binding activity of a LexA‐like repressor and its role in DNA damage induction of the recA gene from Mycobacterium smegmatis [PDF]
Steven I. Durbach+2 more
openalex +1 more source